Gene name: LAT1
Reference locus (S288C): YNL071W
Gene biotype: protein_coding
Description: Pyruvate dehydrogenase e2 component (dihydrolipoamide acetyltransferase); Dihydrolipoamide acetyltransferase component (E2) of the PDC; the pyruvate dehydrogenase complex (PDC) catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA
Top 10 interactors (score): PDB1 (0.999); LPD1 (0.999); PDA1 (0.999); IRC15 (0.998); KGD2 (0.997); LSC1 (0.993); CIT2 (0.989); CIT1 (0.987); GCV3 (0.985); CIT3 (0.984); KGD1 (0.983); AIM22 (0.97); ERG10 (0.969); LSC2 (0.965); ACS2 (0.962); ACS1 (0.958); PDX1 (0.954); ACH1 (0.938); ACC1 (0.918); MLS1 (0.918)
Homologues (species, bitscore): DLAT (Homo sapiens, 375.6); Dlat (Mus musculus, 377.5); dlat (Danio rerio, 379.0); dlat (Xenopus tropicalis, 378.3); CG5261 (Drosophila melanogaster, 348.2); dlat-1 (Caenorhabditis elegans, 375.6); AT1G54220 (Arabidopsis thaliana, 358.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:485193-486641:+ | gene-YNL071W_AKU4011 | rna-NM_001182909.3_AKU4011 | cds-NP_014328.3_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:389212-390660:+ | gene-YNL071W_BG1 | rna-NM_001182909.3_BG1 | cds-NP_014328.3_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:495919-497367:+ | gene-YNL071W_Bruggeman | rna-NM_001182909.3_Bruggeman | cds-NP_014328.3_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:538919-540367:+ | gene-YNL071W_CAT1 | rna-NM_001182909.3_CAT1 | cds-NP_014328.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:485861-487309:+ | gene-YNL071W_CBS1585 | rna-NM_001182909.3_CBS1585 | cds-NP_014328.3_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:554276-555724:+ | gene-YNL071W_CBS436 | rna-NM_001182909.3_CBS436 | cds-NP_014328.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:480955-482403:+ | gene-YNL071W_CBS6412 | rna-NM_001182909.3_CBS6412 | cds-NP_014328.3_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:482271-483719:+ | gene-YNL071W_CBS6413 | rna-NM_001182909.3_CBS6413 | cds-NP_014328.3_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:485347-486795:+ | gene-YNL071W_CENPK1137D | rna-NM_001182909.3_CENPK1137D | cds-NP_014328.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:488012-489460:+ | gene-YNL071W_EthanolRed | rna-NM_001182909.3_EthanolRed | cds-NP_014328.3_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:478537-479985:+ | gene-YNL071W_FaliES1 | rna-NM_001182909.3_FaliES1 | cds-NP_014328.3_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000001.1:4974-6422:+ | gene-YNL071W_JAY291 | rna-NM_001182909.3_JAY291 | cds-NP_014328.3_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:492082-493530:+ | gene-YNL071W_MUCL30387 | rna-NM_001182909.3_MUCL30387 | cds-NP_014328.3_MUCL30387 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:527481-528929:+ | gene-YNL071W_MUCL30388 | rna-NM_001182909.3_MUCL30388 | cds-NP_014328.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:483263-484711:+ | gene-YNL071W_MUCL39482 | rna-NM_001182909.3_MUCL39482 | cds-NP_014328.3_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:487191-488639:+ | gene-YNL071W_MUCL42920 | rna-NM_001182909.3_MUCL42920 | cds-NP_014328.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:491492-492940:+ | gene-YNL071W_NCIM3186 | rna-NM_001182909.3_NCIM3186 | cds-NP_014328.3_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:485315-486763:+ | gene-YNL071W_NCYC1407 | rna-NM_001182909.3_NCYC1407 | cds-NP_014328.3_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:488551-489999:+ | gene-YNL071W_PE2H3 | rna-NM_001182909.3_PE2H3 | cds-NP_014328.3_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:483626-485074:+ | gene-YNL071W_PE2H4 | rna-NM_001182909.3_PE2H4 | cds-NP_014328.3_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:491523-492971:+ | gene-YNL071W_S288C | rna-NM_001182909.3_S288C | cds-NP_014328.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000024.1:76478-77926:+ | gene-YNL071W_SA1 | rna-NM_001182909.3_SA1 | cds-NP_014328.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:479412-480860:+ | gene-YNL071W_ThermosaccDry | rna-NM_001182909.3_ThermosaccDry | cds-NP_014328.3_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:498530-499978:+ | gene-YNL071W_VR1 | rna-NM_001182909.3_VR1 | cds-NP_014328.3_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:388762-390210:+ | gene-YNL071W_ZTW1 | rna-NM_001182909.3_ZTW1 | cds-NP_014328.3_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:494957-496393:+ | gene-YNL071W_Sparadoxus | rna-NM_001182909.3_Sparadoxus | cds-NP_014328.3_Sparadoxus | 91.0 | 99.1 | Verified | 1 | 1 | 1 | False | True | False | False | False |