Gene name: LAP3
Reference locus (S288C): YNL239W
Gene biotype: protein_coding
Description: Cysteine proteinase 1, mitochondrial; Cysteine aminopeptidase with homocysteine-thiolactonase activity; protects cells against homocysteine toxicity; has bleomycin hydrolase activity in vitro; transcription is regulated by galactose via Gal4p; orthologous to human BLMH
Top 10 interactors (score): NPY1 (0.961); PRD1 (0.836); APE2 (0.836); GAL80 (0.745); AAP1 (0.73); YMR099C (0.711); YIL154C (0.671); AAT1 (0.664); PDI1 (0.66); GAL2 (0.647); TMA108 (0.634); GAL4 (0.629); RPN2 (0.602); MIG1 (0.601); AIM2 (0.593); LAP2 (0.569); GCV2 (0.566); APE4 (0.553); STE23 (0.549); KEX2 (0.546)
Homologues (species, bitscore): BLMH (Homo sapiens, 326.6); Blmh (Mus musculus, 328.6); blmh (Danio rerio, 315.1); blmh (Xenopus tropicalis, 170.2); CG1440 (Drosophila melanogaster, 334.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:194348-195712:+ | gene-YNL239W_AKU4011 | rna-NM_001183077.1_AKU4011 | cds-NP_014160.2_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:98291-99655:+ | gene-YNL239W_BG1 | rna-NM_001183077.1_BG1 | cds-NP_014160.2_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:204150-205514:+ | gene-YNL239W_Bruggeman | rna-NM_001183077.1_Bruggeman | cds-NP_014160.2_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:211450-212814:+ | gene-YNL239W_CAT1 | rna-NM_001183077.1_CAT1 | cds-NP_014160.2_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:194745-196109:+ | gene-YNL239W_CBS1585 | rna-NM_001183077.1_CBS1585 | cds-NP_014160.2_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:189833-191197:+ | gene-YNL239W_CBS436 | rna-NM_001183077.1_CBS436 | cds-NP_014160.2_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:190778-192142:+ | gene-YNL239W_CBS6412 | rna-NM_001183077.1_CBS6412 | cds-NP_014160.2_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:191427-192791:+ | gene-YNL239W_CBS6413 | rna-NM_001183077.1_CBS6413 | cds-NP_014160.2_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:194380-195744:+ | gene-YNL239W_CENPK1137D | rna-NM_001183077.1_CENPK1137D | cds-NP_014160.2_CENPK1137D | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:191997-193361:+ | gene-YNL239W_EthanolRed | rna-NM_001183077.1_EthanolRed | cds-NP_014160.2_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:186739-188103:+ | gene-YNL239W_FaliES1 | rna-NM_001183077.1_FaliES1 | cds-NP_014160.2_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000082.1:97882-99246:+ | gene-YNL239W_JAY291 | rna-NM_001183077.1_JAY291 | cds-NP_014160.2_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:199933-201297:+ | gene-YNL239W_MUCL30387 | rna-NM_001183077.1_MUCL30387 | cds-NP_014160.2_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:198518-199882:+ | gene-YNL239W_MUCL30388 | rna-NM_001183077.1_MUCL30388 | cds-NP_014160.2_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:192235-193599:+ | gene-YNL239W_MUCL39482 | rna-NM_001183077.1_MUCL39482 | cds-NP_014160.2_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:194490-195854:+ | gene-YNL239W_MUCL42920 | rna-NM_001183077.1_MUCL42920 | cds-NP_014160.2_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:200538-201902:+ | gene-YNL239W_NCIM3186 | rna-NM_001183077.1_NCIM3186 | cds-NP_014160.2_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:194324-195688:+ | gene-YNL239W_NCYC1407 | rna-NM_001183077.1_NCYC1407 | cds-NP_014160.2_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:191225-192589:+ | gene-YNL239W_PE2H3 | rna-NM_001183077.1_PE2H3 | cds-NP_014160.2_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:190613-191977:+ | gene-YNL239W_PE2H4 | rna-NM_001183077.1_PE2H4 | cds-NP_014160.2_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:200569-201933:+ | gene-YNL239W_S288C | rna-NM_001183077.1_S288C | cds-NP_014160.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000040.1:50368-51732:- | gene-YNL239W_SA1 | rna-NM_001183077.1_SA1 | cds-NP_014160.2_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:187595-188959:+ | gene-YNL239W_ThermosaccDry | rna-NM_001183077.1_ThermosaccDry | cds-NP_014160.2_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:206483-207847:+ | gene-YNL239W_VR1 | rna-NM_001183077.1_VR1 | cds-NP_014160.2_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:97914-99278:+ | gene-YNL239W_ZTW1 | rna-NM_001183077.1_ZTW1 | cds-NP_014160.2_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:197902-199266:+ | gene-YNL239W_Sparadoxus | rna-NM_001183077.1_Sparadoxus | cds-NP_014160.2_Sparadoxus | 91.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |