Gene name: LAP2
Reference locus (S288C): YNL045W
Gene biotype: protein_coding
Description: Leukotriene A-4 hydrolase homolog; Leucyl aminopeptidase yscIV with epoxide hydrolase activity; metalloenzyme containing one zinc atom; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; also known as leukotriene A4 hydrolase
Top 10 interactors (score): DSF1 (0.896); MAN2 (0.893); CHM7 (0.817); URA6 (0.791); SRC1 (0.76); HEH2 (0.749); DUG1 (0.747); COS6 (0.695); CEM1 (0.683); TAF2 (0.676); GEP7 (0.676); YIP1 (0.654); POM33 (0.649); YMR315W (0.609); DUG2 (0.605); GUA1 (0.593); POM152 (0.591); MOD5 (0.588); PGM2 (0.576); CCM1 (0.571)
Homologues (species, bitscore): LTA4H (Homo sapiens, 435.3); Lta4h (Mus musculus, 428.3); lta4h (Danio rerio, 417.2); lta4h (Xenopus tropicalis, 427.2); DmelCG10602 (Drosophila melanogaster, 368.6); ZC416.6 (Caenorhabditis elegans, 384.0); AT5G13520 (Arabidopsis thaliana, 290.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:530763-532778:+ | gene-YNL045W_AKU4011 | rna-NM_001182884.1_AKU4011 | cds-NP_014353.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:434723-436738:+ | gene-YNL045W_BG1 | rna-NM_001182884.1_BG1 | cds-NP_014353.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:547873-549888:+ | gene-YNL045W_Bruggeman | rna-NM_001182884.1_Bruggeman | cds-NP_014353.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:584435-586450:+ | gene-YNL045W_CAT1 | rna-NM_001182884.1_CAT1 | cds-NP_014353.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:531434-533449:+ | gene-YNL045W_CBS1585 | rna-NM_001182884.1_CBS1585 | cds-NP_014353.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:599683-601698:+ | gene-YNL045W_CBS436 | rna-NM_001182884.1_CBS436 | cds-NP_014353.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:526526-528541:+ | gene-YNL045W_CBS6412 | rna-NM_001182884.1_CBS6412 | cds-NP_014353.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:527844-529859:+ | gene-YNL045W_CBS6413 | rna-NM_001182884.1_CBS6413 | cds-NP_014353.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:536550-538565:+ | gene-YNL045W_CENPK1137D | rna-NM_001182884.1_CENPK1137D | cds-NP_014353.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:533586-535601:+ | gene-YNL045W_EthanolRed | rna-NM_001182884.1_EthanolRed | cds-NP_014353.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:524111-526126:+ | gene-YNL045W_FaliES1 | rna-NM_001182884.1_FaliES1 | cds-NP_014353.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000040.1:39153-41168:+ | gene-YNL045W_JAY291 | rna-NM_001182884.1_JAY291 | cds-NP_014353.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:544207-546222:+ | gene-YNL045W_MUCL30387 | rna-NM_001182884.1_MUCL30387 | cds-NP_014353.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:573627-575642:+ | gene-YNL045W_MUCL30388 | rna-NM_001182884.1_MUCL30388 | cds-NP_014353.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:528850-530865:+ | gene-YNL045W_MUCL39482 | rna-NM_001182884.1_MUCL39482 | cds-NP_014353.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:532922-534937:+ | gene-YNL045W_MUCL42920 | rna-NM_001182884.1_MUCL42920 | cds-NP_014353.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:542932-544947:+ | gene-YNL045W_NCIM3186 | rna-NM_001182884.1_NCIM3186 | cds-NP_014353.1_NCIM3186 | 94.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:530902-532917:+ | gene-YNL045W_NCYC1407 | rna-NM_001182884.1_NCYC1407 | cds-NP_014353.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:534070-536085:+ | gene-YNL045W_PE2H3 | rna-NM_001182884.1_PE2H3 | cds-NP_014353.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:529145-531160:+ | gene-YNL045W_PE2H4 | rna-NM_001182884.1_PE2H4 | cds-NP_014353.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:542963-544978:+ | gene-YNL045W_S288C | rna-NM_001182884.1_S288C | cds-NP_014353.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000024.1:121995-124010:+ | gene-YNL045W_SA1 | rna-NM_001182884.1_SA1 | cds-NP_014353.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:524986-527001:+ | gene-YNL045W_ThermosaccDry | rna-NM_001182884.1_ThermosaccDry | cds-NP_014353.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:544031-546046:+ | gene-YNL045W_VR1 | rna-NM_001182884.1_VR1 | cds-NP_014353.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:434307-436322:+ | gene-YNL045W_ZTW1 | rna-NM_001182884.1_ZTW1 | cds-NP_014353.1_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:540243-542255:+ | gene-YNL045W_Sparadoxus | rna-NM_001182884.1_Sparadoxus | cds-NP_014353.1_Sparadoxus | 89.8 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |