Gene name: LAM5
Reference locus (S288C): YFL042C
Gene biotype: protein_coding
Description: Membrane-anchored lipid-binding protein LAM5; Putative sterol transfer protein; one of six StART-like domain-containing proteins in yeast that may be involved in sterol transfer between intracellular membranes; conserved across eukaryotes; has both GRAM and StART-like (VASt) domains; localizes to membrane contact sites throughout the cell, including nucleus-vacuole junctions and ER-mitochondrial contact sites
Top 10 interactors (score): YDL034W (0.813); LAM1 (0.778); SIP3 (0.769); YER137C (0.748); TOM71 (0.694); COP1 (0.609); ATP23 (0.552); NVJ2 (0.534); PRY1 (0.526); YNL092W (0.508); MAM33 (0.499); SAY1 (0.497); MRX8 (0.485); ARL1 (0.461); UIP5 (0.45); YIL067C (0.45); YGR017W (0.438); SEC21 (0.433); RET2 (0.424)
Homologues (species, bitscore): GRAMD1A (Homo sapiens, 120.9); Gramd1a (Mus musculus, 117.9); gramd1b (Danio rerio, 117.1); GRAMD1A (Xenopus tropicalis, 112.8); CG34394 (Drosophila melanogaster, 112.5); ZC328.3 (Caenorhabditis elegans, 105.5); VAD1 (Arabidopsis thaliana, 87.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005300.1:42057-44081:- | gene-YFL042C_AKU4011 | rna-NM_001179924.1_AKU4011 | cds-NP_116611.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000182.1:25712-27736:+ | gene-YFL042C_BG1 | rna-NM_001179924.1_BG1 | cds-NP_116611.1_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005508.1:40435-42459:- | gene-YFL042C_Bruggeman | rna-NM_001179924.1_Bruggeman | cds-NP_116611.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005524.1:45823-47847:- | gene-YFL042C_CAT1 | rna-NM_001179924.1_CAT1 | cds-NP_116611.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005364.1:42734-44758:- | gene-YFL042C_CBS1585 | rna-NM_001179924.1_CBS1585 | cds-NP_116611.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005348.1:16368-18392:- | gene-YFL042C_CBS436 | rna-NM_001179924.1_CBS436 | cds-NP_116611.1_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005332.1:42974-44998:- | gene-YFL042C_CBS6412 | rna-NM_001179924.1_CBS6412 | cds-NP_116611.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005316.1:45135-47159:- | gene-YFL042C_CBS6413 | rna-NM_001179924.1_CBS6413 | cds-NP_116611.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001527.1:42046-44070:- | gene-YFL042C_CENPK1137D | rna-NM_001179924.1_CENPK1137D | cds-NP_116611.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005476.1:41401-43425:- | gene-YFL042C_EthanolRed | rna-NM_001179924.1_EthanolRed | cds-NP_116611.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005540.1:42609-44633:- | gene-YFL042C_FaliES1 | rna-NM_001179924.1_FaliES1 | cds-NP_116611.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000448.1:51066-53090:- | gene-YFL042C_JAY291 | rna-NM_001179924.1_JAY291 | cds-NP_116611.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005412.1:43024-45048:- | gene-YFL042C_MUCL30387 | rna-NM_001179924.1_MUCL30387 | cds-NP_116611.1_MUCL30387 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005444.1:40047-42071:- | gene-YFL042C_MUCL30388 | rna-NM_001179924.1_MUCL30388 | cds-NP_116611.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005284.1:41250-43274:- | gene-YFL042C_MUCL39482 | rna-NM_001179924.1_MUCL39482 | cds-NP_116611.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005428.1:38953-40977:- | gene-YFL042C_MUCL42920 | rna-NM_001179924.1_MUCL42920 | cds-NP_116611.1_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011815.1:45719-47743:- | gene-YFL042C_NCIM3186 | rna-NM_001179924.1_NCIM3186 | cds-NP_116611.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005268.1:42327-44351:- | gene-YFL042C_NCYC1407 | rna-NM_001179924.1_NCYC1407 | cds-NP_116611.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994145.1:62220-64244:- | gene-YFL042C_PE2H3 | rna-NM_001179924.1_PE2H3 | cds-NP_116611.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999877.1:61771-63795:- | gene-YFL042C_PE2H4 | rna-NM_001179924.1_PE2H4 | cds-NP_116611.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001138.5:45720-47744:- | gene-YFL042C_S288C | rna-NM_001179924.1_S288C | cds-NP_116611.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:287889-289913:+ | gene-YFL042C_SA1 | rna-NM_001179924.1_SA1 | cds-NP_116611.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005492.1:41797-43821:- | gene-YFL042C_ThermosaccDry | rna-NM_001179924.1_ThermosaccDry | cds-NP_116611.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005460.1:50340-52364:- | gene-YFL042C_VR1 | rna-NM_001179924.1_VR1 | cds-NP_116611.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000012.1:27094-29118:- | gene-YFL042C_ZTW1 | rna-NM_001179924.1_ZTW1 | cds-NP_116611.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047492.1:66108-68132:- | gene-YFL042C_Sparadoxus | rna-NM_001179924.1_Sparadoxus | cds-NP_116611.1_Sparadoxus | 89.2 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |