Gene name: LAG2
Reference locus (S288C): YOL025W
Gene biotype: protein_coding
Description: Cullin-associated NEDD8-dissociated protein 1 homolog; Protein that negatively regulates the SCF E3-ubiquitin ligase; regulates by interacting with and preventing neddyation of the cullin subunit, Cdc53p; longevity determinant that is preferentially expressed in young cells; similar to mammalian Cand1
Top 10 interactors (score): CDC53 (0.942); RUB1 (0.938); DCN1 (0.937); HRT1 (0.837); SKP1 (0.802); CDC34 (0.75); RRI1 (0.671); UBC12 (0.656); UBA3 (0.566); MET30 (0.559); RTT101 (0.517); ULA1 (0.489); TOM1 (0.421)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:259351-261333:+ | gene-YOL025W_AKU4011 | rna-NM_001183279.1_AKU4011 | cds-NP_014617.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000152.1:74939-76921:+ | gene-YOL025W_BG1 | rna-NM_001183279.1_BG1 | cds-NP_014617.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:262172-264154:+ | gene-YOL025W_Bruggeman | rna-NM_001183279.1_Bruggeman | cds-NP_014617.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:260047-262029:+ | gene-YOL025W_CAT1 | rna-NM_001183279.1_CAT1 | cds-NP_014617.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:254029-256011:+ | gene-YOL025W_CBS1585 | rna-NM_001183279.1_CBS1585 | cds-NP_014617.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:258265-260247:+ | gene-YOL025W_CBS436 | rna-NM_001183279.1_CBS436 | cds-NP_014617.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:253385-255367:+ | gene-YOL025W_CBS6412 | rna-NM_001183279.1_CBS6412 | cds-NP_014617.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:260912-262894:+ | gene-YOL025W_CBS6413 | rna-NM_001183279.1_CBS6413 | cds-NP_014617.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:274657-276639:+ | gene-YOL025W_CENPK1137D | rna-NM_001183279.1_CENPK1137D | cds-NP_014617.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:256178-258160:+ | gene-YOL025W_EthanolRed | rna-NM_001183279.1_EthanolRed | cds-NP_014617.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:259505-261487:+ | gene-YOL025W_FaliES1 | rna-NM_001183279.1_FaliES1 | cds-NP_014617.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000018.1:5256-7238:- | gene-YOL025W_JAY291 | rna-NM_001183279.1_JAY291 | cds-NP_014617.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:266105-268087:+ | gene-YOL025W_MUCL30387 | rna-NM_001183279.1_MUCL30387 | cds-NP_014617.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:269547-271529:+ | gene-YOL025W_MUCL30388 | rna-NM_001183279.1_MUCL30388 | cds-NP_014617.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:261514-263496:+ | gene-YOL025W_MUCL39482 | rna-NM_001183279.1_MUCL39482 | cds-NP_014617.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:276430-278412:+ | gene-YOL025W_MUCL42920 | rna-NM_001183279.1_MUCL42920 | cds-NP_014617.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:274846-276828:+ | gene-YOL025W_NCIM3186 | rna-NM_001183279.1_NCIM3186 | cds-NP_014617.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:268246-270228:+ | gene-YOL025W_NCYC1407 | rna-NM_001183279.1_NCYC1407 | cds-NP_014617.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:250633-252615:+ | gene-YOL025W_PE2H3 | rna-NM_001183279.1_PE2H3 | cds-NP_014617.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:261607-263589:+ | gene-YOL025W_PE2H4 | rna-NM_001183279.1_PE2H4 | cds-NP_014617.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:274957-276939:+ | gene-YOL025W_S288C | rna-NM_001183279.1_S288C | cds-NP_014617.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:242957-244939:+ | gene-YOL025W_SA1 | rna-NM_001183279.1_SA1 | cds-NP_014617.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:258076-260058:+ | gene-YOL025W_ThermosaccDry | rna-NM_001183279.1_ThermosaccDry | cds-NP_014617.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:258107-260089:+ | gene-YOL025W_VR1 | rna-NM_001183279.1_VR1 | cds-NP_014617.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000031.1:257672-259654:+ | gene-YOL025W_ZTW1 | rna-NM_001183279.1_ZTW1 | cds-NP_014617.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:266062-268044:+ | gene-YOL025W_Sparadoxus | rna-NM_001183279.1_Sparadoxus | cds-NP_014617.1_Sparadoxus | 86.3 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |