KTI12 (YKL110C)


Gene profile

Gene name: KTI12
Reference locus (S288C): YKL110C
Gene biotype: protein_coding

Description: Protein that plays a role in modification of tRNA wobble nucleosides; protein plays role in tRNA wobble nucleoside modification with Elongator complex; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p; Belongs to the KTI12 family

Top 10 interactors (score): ELP3 (0.998); IKI3 (0.997); ELP2 (0.989); ELP4 (0.976); DST1 (0.972); IKI1 (0.966); NCS6 (0.935); UBA4 (0.933); KTI11 (0.919); URM1 (0.893); SIT4 (0.87); ELP6 (0.86); NCS2 (0.855); HRR25 (0.852); ATS1 (0.831); TRM9 (0.831); SAP190 (0.806); SAP185 (0.786); HHF2 (0.78); HHF1 (0.78)

Homologues (species, bitscore): KTI12 (Homo sapiens, 107.5); Kti12 (Mus musculus, 112.8); kti12 (Danio rerio, 156.8); kti12 (Xenopus tropicalis, 165.6); CG3587 (Drosophila melanogaster, 115.5); Y57G11C.43 (Caenorhabditis elegans, 133.3); KTI12 (Arabidopsis thaliana, 117.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:215507-216448:- gene-YKL110C_AKU4011 rna-NM_001179676.1_AKU4011 cds-NP_012812.1_AKU4011 99.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000030.1:192631-193572:- gene-YKL110C_BG1 rna-NM_001179676.1_BG1 cds-NP_012812.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:233431-234372:- gene-YKL110C_Bruggeman rna-NM_001179676.1_Bruggeman cds-NP_012812.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:228477-229418:- gene-YKL110C_CAT1 rna-NM_001179676.1_CAT1 cds-NP_012812.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:227738-228679:- gene-YKL110C_CBS1585 rna-NM_001179676.1_CBS1585 cds-NP_012812.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:226327-227268:- gene-YKL110C_CBS436 rna-NM_001179676.1_CBS436 cds-NP_012812.1_CBS436 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:212369-213310:- gene-YKL110C_CBS6412 rna-NM_001179676.1_CBS6412 cds-NP_012812.1_CBS6412 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:228203-229144:- gene-YKL110C_CBS6413 rna-NM_001179676.1_CBS6413 cds-NP_012812.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:228581-229522:- gene-YKL110C_CENPK1137D rna-NM_001179676.1_CENPK1137D cds-NP_012812.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:226184-227125:- gene-YKL110C_EthanolRed rna-NM_001179676.1_EthanolRed cds-NP_012812.1_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:226997-227938:- gene-YKL110C_FaliES1 rna-NM_001179676.1_FaliES1 cds-NP_012812.1_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000357.1:49345-50286:- gene-YKL110C_JAY291 rna-NM_001179676.1_JAY291 cds-NP_012812.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:235234-236175:- gene-YKL110C_MUCL30387 rna-NM_001179676.1_MUCL30387 cds-NP_012812.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:229613-230554:- gene-YKL110C_MUCL30388 rna-NM_001179676.1_MUCL30388 cds-NP_012812.1_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:227534-228475:- gene-YKL110C_MUCL39482 rna-NM_001179676.1_MUCL39482 cds-NP_012812.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:231909-232850:- gene-YKL110C_MUCL42920 rna-NM_001179676.1_MUCL42920 cds-NP_012812.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:228928-229869:- gene-YKL110C_NCIM3186 rna-NM_001179676.1_NCIM3186 cds-NP_012812.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:227724-228665:- gene-YKL110C_NCYC1407 rna-NM_001179676.1_NCYC1407 cds-NP_012812.1_NCYC1407 99.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:234817-235758:- gene-YKL110C_PE2H3 rna-NM_001179676.1_PE2H3 cds-NP_012812.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:231106-232047:- gene-YKL110C_PE2H4 rna-NM_001179676.1_PE2H4 cds-NP_012812.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:228939-229880:- gene-YKL110C_S288C rna-NM_001179676.1_S288C cds-NP_012812.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000008.1:145065-146006:- gene-YKL110C_SA1 rna-NM_001179676.1_SA1 cds-NP_012812.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:227697-228638:- gene-YKL110C_ThermosaccDry rna-NM_001179676.1_ThermosaccDry cds-NP_012812.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:227077-228018:- gene-YKL110C_VR1 rna-NM_001179676.1_VR1 cds-NP_012812.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:226271-227212:- gene-YKL110C_ZTW1 rna-NM_001179676.1_ZTW1 cds-NP_012812.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:243242-244183:- gene-YKL110C_Sparadoxus rna-NM_001179676.1_Sparadoxus cds-NP_012812.1_Sparadoxus 91.2 100.0 Verified 1 1 1 False True False False False

Additional files