Gene name: KTI11
Reference locus (S288C): YBL071W-A
Gene biotype: protein_coding
Description: Diphthamide biosynthesis protein 3; Zn-ribbon protein that co-purifies with Dph1 and Dph2; in a complex required for synthesis of diphthamide on translation factor eEF2 and with Elongator subunits Iki3p, Elp2p, and Elp3p; involved in modification of wobble nucleosides in tRNAs; forms a stable heterodimer with Ats1p; Belongs to the DPH3 family
Top 10 interactors (score): DPH2 (0.999); DPH1 (0.999); ATS1 (0.999); DPH5 (0.998); ELP3 (0.992); ELP2 (0.985); DPH6 (0.98); RRT2 (0.974); IKI3 (0.974); EFT2 (0.967); TRM112 (0.962); ELP4 (0.95); JJJ3 (0.919); KTI12 (0.919); EFT1 (0.915); TRM9 (0.911); URM1 (0.888); HRR25 (0.873); MCM5 (0.868); SAP185 (0.864)
Homologues (species, bitscore): DPH3 (Homo sapiens, 71.6); Dph3 (Mus musculus, 70.9); dph3 (Danio rerio, 75.1); dph3 (Xenopus tropicalis, 75.1); CG14701 (Drosophila melanogaster, 80.9); dph-3 (Caenorhabditis elegans, 72.0); AT2G15910 (Arabidopsis thaliana, 82.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:83556-83804:+ | gene-YBL071W-A_AKU4011 | rna-NM_001184454.1_AKU4011 | cds-NP_660100.1_AKU4011 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:74417-74665:+ | gene-YBL071W-A_BG1 | rna-NM_001184454.1_BG1 | cds-NP_660100.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:84171-84419:+ | gene-YBL071W-A_Bruggeman | rna-NM_001184454.1_Bruggeman | cds-NP_660100.1_Bruggeman | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:86811-87059:+ | gene-YBL071W-A_CAT1 | rna-NM_001184454.1_CAT1 | cds-NP_660100.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:76123-76371:+ | gene-YBL071W-A_CBS1585 | rna-NM_001184454.1_CBS1585 | cds-NP_660100.1_CBS1585 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:84632-84880:+ | gene-YBL071W-A_CBS436 | rna-NM_001184454.1_CBS436 | cds-NP_660100.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:74629-74877:+ | gene-YBL071W-A_CBS6412 | rna-NM_001184454.1_CBS6412 | cds-NP_660100.1_CBS6412 | 98.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:81701-81949:+ | gene-YBL071W-A_CBS6413 | rna-NM_001184454.1_CBS6413 | cds-NP_660100.1_CBS6413 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:83737-83985:+ | gene-YBL071W-A_CENPK1137D | rna-NM_001184454.1_CENPK1137D | cds-NP_660100.1_CENPK1137D | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:97554-97802:+ | gene-YBL071W-A_EthanolRed | rna-NM_001184454.1_EthanolRed | cds-NP_660100.1_EthanolRed | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:98407-98655:+ | gene-YBL071W-A_FaliES1 | rna-NM_001184454.1_FaliES1 | cds-NP_660100.1_FaliES1 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000072.1:1031-1279:+ | gene-YBL071W-A_JAY291 | rna-NM_001184454.1_JAY291 | cds-NP_660100.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:83545-83793:+ | gene-YBL071W-A_MUCL30387 | rna-NM_001184454.1_MUCL30387 | cds-NP_660100.1_MUCL30387 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:84824-85072:+ | gene-YBL071W-A_MUCL30388 | rna-NM_001184454.1_MUCL30388 | cds-NP_660100.1_MUCL30388 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:76304-76552:+ | gene-YBL071W-A_MUCL39482 | rna-NM_001184454.1_MUCL39482 | cds-NP_660100.1_MUCL39482 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:83140-83388:+ | gene-YBL071W-A_MUCL42920 | rna-NM_001184454.1_MUCL42920 | cds-NP_660100.1_MUCL42920 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:89775-90023:+ | gene-YBL071W-A_NCIM3186 | rna-NM_001184454.1_NCIM3186 | cds-NP_660100.1_NCIM3186 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:77446-77694:+ | gene-YBL071W-A_NCYC1407 | rna-NM_001184454.1_NCYC1407 | cds-NP_660100.1_NCYC1407 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:83706-83954:+ | gene-YBL071W-A_PE2H3 | rna-NM_001184454.1_PE2H3 | cds-NP_660100.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:81350-81598:+ | gene-YBL071W-A_PE2H4 | rna-NM_001184454.1_PE2H4 | cds-NP_660100.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:89978-90226:+ | gene-YBL071W-A_S288C | rna-NM_001184454.1_S288C | cds-NP_660100.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:74085-74333:+ | gene-YBL071W-A_SA1 | rna-NM_001184454.1_SA1 | cds-NP_660100.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:98368-98616:+ | gene-YBL071W-A_ThermosaccDry | rna-NM_001184454.1_ThermosaccDry | cds-NP_660100.1_ThermosaccDry | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:80538-80786:+ | gene-YBL071W-A_VR1 | rna-NM_001184454.1_VR1 | cds-NP_660100.1_VR1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:75087-75335:+ | gene-YBL071W-A_ZTW1 | rna-NM_001184454.1_ZTW1 | cds-NP_660100.1_ZTW1 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:109755-110003:+ | gene-YBL071W-A_Sparadoxus | rna-NM_001184454.1_Sparadoxus | cds-NP_660100.1_Sparadoxus | 89.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |