Gene name: KSP1
Reference locus (S288C): YHR082C
Gene biotype: protein_coding
Description: Serine/threonine-protein kinase KSP1; Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily
Top 10 interactors (score): KOG1 (0.865); MRK1 (0.832); TOK1 (0.78); MRN1 (0.721); TOR1 (0.714); YBL081W (0.711); SDD4 (0.708); DPH6 (0.687); SKY1 (0.681); LST8 (0.676); PUF2 (0.647); WHI2 (0.638); KSS1 (0.636); CAF20 (0.604); SRM1 (0.603); SSD1 (0.59); LGE1 (0.584); PHO85 (0.577); NSP1 (0.577); ATG1 (0.576)
Homologues (species, bitscore): MARK1 (Homo sapiens, 97.1); Gm7168 (Mus musculus, 111.7); mark2b (Danio rerio, 97.8); mark2 (Xenopus tropicalis, 97.8); KP78b (Drosophila melanogaster, 97.8); unc-51 (Caenorhabditis elegans, 100.5); SOS2 (Arabidopsis thaliana, 88.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005302.1:254870-257959:- | gene-YHR082C_AKU4011 | rna-NM_001179212.1_AKU4011 | cds-NP_011950.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000053.1:175217-178306:- | gene-YHR082C_BG1 | rna-NM_001179212.1_BG1 | cds-NP_011950.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005510.1:262697-265786:- | gene-YHR082C_Bruggeman | rna-NM_001179212.1_Bruggeman | cds-NP_011950.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005526.1:257840-260929:- | gene-YHR082C_CAT1 | rna-NM_001179212.1_CAT1 | cds-NP_011950.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005366.1:253912-257001:- | gene-YHR082C_CBS1585 | rna-NM_001179212.1_CBS1585 | cds-NP_011950.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005350.1:251773-254862:- | gene-YHR082C_CBS436 | rna-NM_001179212.1_CBS436 | cds-NP_011950.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005334.1:257259-260348:- | gene-YHR082C_CBS6412 | rna-NM_001179212.1_CBS6412 | cds-NP_011950.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005318.1:254951-258040:- | gene-YHR082C_CBS6413 | rna-NM_001179212.1_CBS6413 | cds-NP_011950.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001529.1:261630-264719:- | gene-YHR082C_CENPK1137D | rna-NM_001179212.1_CENPK1137D | cds-NP_011950.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:314477-317566:- | gene-YHR082C_EthanolRed | rna-NM_001179212.1_EthanolRed | cds-NP_011950.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005542.1:255281-258370:- | gene-YHR082C_FaliES1 | rna-NM_001179212.1_FaliES1 | cds-NP_011950.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000394.1:38006-41095:- | gene-YHR082C_JAY291 | rna-NM_001179212.1_JAY291 | cds-NP_011950.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005414.1:262217-265306:- | gene-YHR082C_MUCL30387 | rna-NM_001179212.1_MUCL30387 | cds-NP_011950.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005446.1:262081-265170:- | gene-YHR082C_MUCL30388 | rna-NM_001179212.1_MUCL30388 | cds-NP_011950.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005286.1:254235-257324:- | gene-YHR082C_MUCL39482 | rna-NM_001179212.1_MUCL39482 | cds-NP_011950.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005430.1:260980-264069:- | gene-YHR082C_MUCL42920 | rna-NM_001179212.1_MUCL42920 | cds-NP_011950.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:268341-271430:- | gene-YHR082C_NCIM3186 | rna-NM_001179212.1_NCIM3186 | cds-NP_011950.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005270.1:256699-259788:- | gene-YHR082C_NCYC1407 | rna-NM_001179212.1_NCYC1407 | cds-NP_011950.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994147.1:256370-259459:- | gene-YHR082C_PE2H3 | rna-NM_001179212.1_PE2H3 | cds-NP_011950.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999879.1:263817-266906:- | gene-YHR082C_PE2H4 | rna-NM_001179212.1_PE2H4 | cds-NP_011950.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:268459-271548:- | gene-YHR082C_S288C | rna-NM_001179212.1_S288C | cds-NP_011950.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000014.1:87440-90529:+ | gene-YHR082C_SA1 | rna-NM_001179212.1_SA1 | cds-NP_011950.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005494.1:256372-259461:- | gene-YHR082C_ThermosaccDry | rna-NM_001179212.1_ThermosaccDry | cds-NP_011950.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005462.1:264245-267334:- | gene-YHR082C_VR1 | rna-NM_001179212.1_VR1 | cds-NP_011950.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000017.1:247925-251014:- | gene-YHR082C_ZTW1 | rna-NM_001179212.1_ZTW1 | cds-NP_011950.1_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047494.1:253691-256777:- | gene-YHR082C_Sparadoxus | rna-NM_001179212.1_Sparadoxus | cds-NP_011950.1_Sparadoxus | 90.3 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |