KSH1 (YNL024C-A)


Gene profile

Gene name: KSH1
Reference locus (S288C): YNL024C-A
Gene biotype: protein_coding

Description: Essential protein suggested to function early in the secretory pathway; inviability is suppressed by overexpression of Golgi protein Tvp23p; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and cytosol respectively; ortholog of human Kish

Top 10 interactors (score): CMC4 (0.896); YJL127C-B (0.733); YIL156W-B (0.716); SKG1 (0.675); HST2 (0.674); YKL033W-A (0.673); PTK1 (0.65); ECM9 (0.616); ERI1 (0.612); SLY1 (0.588); YER039C-A (0.577); YSF3 (0.572); RRT8 (0.571); SPO24 (0.564); YJL107C (0.564); YPR089W (0.561); PIR5 (0.526); HSK3 (0.513); TPH3 (0.499); HVG1 (0.492)

Homologues (species, bitscore): TMEM167A (Homo sapiens, 91.3); Tmem167 (Mus musculus, 90.5); tmem167a (Danio rerio, 52.0); tmem167a (Xenopus tropicalis, 87.0); ksh (Drosophila melanogaster, 87.0); AT5G20165 (Arabidopsis thaliana, 50.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:569061-569279:- gene-YNL024C-A_AKU4011 rna-NM_001184619.3_AKU4011 cds-NP_878158.3_AKU4011 99.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:470864-471082:+ gene-YNL024C-A_BG1 rna-NM_001184619.3_BG1 cds-NP_878158.3_BG1 99.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:586482-586700:- gene-YNL024C-A_Bruggeman rna-NM_001184619.3_Bruggeman cds-NP_878158.3_Bruggeman 99.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:621931-622149:- gene-YNL024C-A_CAT1 rna-NM_001184619.3_CAT1 cds-NP_878158.3_CAT1 99.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:574745-574963:- gene-YNL024C-A_CBS1585 rna-NM_001184619.3_CBS1585 cds-NP_878158.3_CBS1585 99.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:637156-637374:- gene-YNL024C-A_CBS436 rna-NM_001184619.3_CBS436 cds-NP_878158.3_CBS436 99.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:564578-564796:- gene-YNL024C-A_CBS6412 rna-NM_001184619.3_CBS6412 cds-NP_878158.3_CBS6412 99.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:565919-566137:- gene-YNL024C-A_CBS6413 rna-NM_001184619.3_CBS6413 cds-NP_878158.3_CBS6413 99.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:580209-580427:- gene-YNL024C-A_CENPK1137D rna-NM_001184619.3_CENPK1137D cds-NP_878158.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:571147-571365:- gene-YNL024C-A_EthanolRed rna-NM_001184619.3_EthanolRed cds-NP_878158.3_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:562171-562389:- gene-YNL024C-A_FaliES1 rna-NM_001184619.3_FaliES1 cds-NP_878158.3_FaliES1 99.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000387.1:11445-11663:+ gene-YNL024C-A_JAY291 rna-NM_001184619.3_JAY291 cds-NP_878158.3_JAY291 99.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:582364-582582:- gene-YNL024C-A_MUCL30387 rna-NM_001184619.3_MUCL30387 cds-NP_878158.3_MUCL30387 99.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:625158-625376:- gene-YNL024C-A_MUCL30388 rna-NM_001184619.3_MUCL30388 cds-NP_878158.3_MUCL30388 99.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:566340-566558:- gene-YNL024C-A_MUCL39482 rna-NM_001184619.3_MUCL39482 cds-NP_878158.3_MUCL39482 99.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:569899-570117:- gene-YNL024C-A_MUCL42920 rna-NM_001184619.3_MUCL42920 cds-NP_878158.3_MUCL42920 99.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:586571-586789:- gene-YNL024C-A_NCIM3186 rna-NM_001184619.3_NCIM3186 cds-NP_878158.3_NCIM3186 98.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:568545-568763:- gene-YNL024C-A_NCYC1407 rna-NM_001184619.3_NCYC1407 cds-NP_878158.3_NCYC1407 99.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:571069-571287:- gene-YNL024C-A_PE2H3 rna-NM_001184619.3_PE2H3 cds-NP_878158.3_PE2H3 99.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:572387-572605:- gene-YNL024C-A_PE2H4 rna-NM_001184619.3_PE2H4 cds-NP_878158.3_PE2H4 99.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:586602-586820:- gene-YNL024C-A_S288C rna-NM_001184619.3_S288C cds-NP_878158.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000109.1:12628-12846:- gene-YNL024C-A_SA1 rna-NM_001184619.3_SA1 cds-NP_878158.3_SA1 99.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:562758-562976:- gene-YNL024C-A_ThermosaccDry rna-NM_001184619.3_ThermosaccDry cds-NP_878158.3_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:579774-579992:+ gene-YNL024C-A_VR1 rna-NM_001184619.3_VR1 cds-NP_878158.3_VR1 99.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:470464-470682:+ gene-YNL024C-A_ZTW1 rna-NM_001184619.3_ZTW1 cds-NP_878158.3_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:577845-578063:- gene-YNL024C-A_Sparadoxus rna-NM_001184619.3_Sparadoxus cds-NP_878158.3_Sparadoxus 96.3 100.0 Verified 1 1 1 True True False False False

Additional files