KOG1 (YHR186C)


Gene profile

Gene name: KOG1
Reference locus (S288C): YHR186C
Gene biotype: protein_coding

Description: Subunit of TORC1; TORC1 is a rapamycin-sensitive complex involved in growth control that contains Tor1p or Tor2p, Lst8p and Tco89p; contains four HEAT repeats and seven WD-40 repeats; may act as a scaffold protein to couple TOR and its effectors; Belongs to the WD repeat RAPTOR family

Top 10 interactors (score): GTR1 (0.999); GTR2 (0.999); TCO89 (0.999); LST8 (0.999); RHB1 (0.999); TOR1 (0.999); TOR2 (0.999); AVO1 (0.997); SCH9 (0.997); TSC11 (0.996); TAP42 (0.992); BIT61 (0.978); GCN2 (0.97); FPR1 (0.97); ATG1 (0.966); AVO2 (0.961); CDC33 (0.948); SKN7 (0.941); YPK3 (0.935); YPK2 (0.923)

Homologues (species, bitscore): RPTOR (Homo sapiens, 769.6); Rptor (Mus musculus, 768.1); rptor (Danio rerio, 764.6); rptor (Xenopus tropicalis, 761.5); raptor (Drosophila melanogaster, 569.7); daf-15 (Caenorhabditis elegans, 421.8); RAPTOR1 (Arabidopsis thaliana, 582.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005302.1:463079-467752:- gene-YHR186C_AKU4011 rna-NM_001179317.1_AKU4011 cds-NP_012056.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000141.1:49997-54670:+ gene-YHR186C_BG1 rna-NM_001179317.1_BG1 cds-NP_012056.1_BG1 99.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005510.1:470321-474994:- gene-YHR186C_Bruggeman rna-NM_001179317.1_Bruggeman cds-NP_012056.1_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005526.1:466596-471269:- gene-YHR186C_CAT1 rna-NM_001179317.1_CAT1 cds-NP_012056.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005366.1:462531-467204:- gene-YHR186C_CBS1585 rna-NM_001179317.1_CBS1585 cds-NP_012056.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005350.1:460471-465144:- gene-YHR186C_CBS436 rna-NM_001179317.1_CBS436 cds-NP_012056.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005334.1:462630-467303:- gene-YHR186C_CBS6412 rna-NM_001179317.1_CBS6412 cds-NP_012056.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005318.1:463921-468594:- gene-YHR186C_CBS6413 rna-NM_001179317.1_CBS6413 cds-NP_012056.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001529.1:469187-473860:- gene-YHR186C_CENPK1137D rna-NM_001179317.1_CENPK1137D cds-NP_012056.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005478.1:521618-526291:- gene-YHR186C_EthanolRed rna-NM_001179317.1_EthanolRed cds-NP_012056.1_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005542.1:464062-468735:- gene-YHR186C_FaliES1 rna-NM_001179317.1_FaliES1 cds-NP_012056.1_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000147.1:9222-13895:- gene-YHR186C_JAY291 rna-NM_001179317.1_JAY291 cds-NP_012056.1_JAY291 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005414.1:471647-476320:- gene-YHR186C_MUCL30387 rna-NM_001179317.1_MUCL30387 cds-NP_012056.1_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005446.1:471070-475743:- gene-YHR186C_MUCL30388 rna-NM_001179317.1_MUCL30388 cds-NP_012056.1_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005286.1:462442-467115:- gene-YHR186C_MUCL39482 rna-NM_001179317.1_MUCL39482 cds-NP_012056.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005430.1:470386-475059:- gene-YHR186C_MUCL42920 rna-NM_001179317.1_MUCL42920 cds-NP_012056.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011817.1:475881-480554:- gene-YHR186C_NCIM3186 rna-NM_001179317.1_NCIM3186 cds-NP_012056.1_NCIM3186 98.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005270.1:464905-469578:- gene-YHR186C_NCYC1407 rna-NM_001179317.1_NCYC1407 cds-NP_012056.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994147.1:464061-468734:- gene-YHR186C_PE2H3 rna-NM_001179317.1_PE2H3 cds-NP_012056.1_PE2H3 99.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999879.1:471488-476161:- gene-YHR186C_PE2H4 rna-NM_001179317.1_PE2H4 cds-NP_012056.1_PE2H4 99.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001140.6:475999-480672:- gene-YHR186C_S288C rna-NM_001179317.1_S288C cds-NP_012056.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000079.1:24148-28821:- gene-YHR186C_SA1 rna-NM_001179317.1_SA1 cds-NP_012056.1_SA1 99.9 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005494.1:465145-469818:- gene-YHR186C_ThermosaccDry rna-NM_001179317.1_ThermosaccDry cds-NP_012056.1_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005462.1:474363-479036:- gene-YHR186C_VR1 rna-NM_001179317.1_VR1 cds-NP_012056.1_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000017.1:455380-460053:- gene-YHR186C_ZTW1 rna-NM_001179317.1_ZTW1 cds-NP_012056.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047494.1:462073-466752:- gene-YHR186C_Sparadoxus rna-NM_001179317.1_Sparadoxus cds-NP_012056.1_Sparadoxus 91.1 99.9 Verified 1 1 1 False True False False False

Additional files