KIN4 (YOR233W)


Gene profile

Gene name: KIN4
Reference locus (S288C): YOR233W
Gene biotype: protein_coding

Description: Serine/threonine-protein kinase KIN4; Serine/threonine protein kinase; inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; KIN4 has a paralog, FRK1, that arose from the whole genome duplication

Top 10 interactors (score): BFA1 (0.995); BUB2 (0.995); TEM1 (0.989); LTE1 (0.983); RTS1 (0.954); SPC72 (0.924); MOB1 (0.92); VPS34 (0.914); VPS15 (0.911); VPS30 (0.907); DYN1 (0.906); KAR9 (0.882); NUD1 (0.879); SPC42 (0.817); NET1 (0.811); SLK19 (0.808); CDC14 (0.807); SIP2 (0.806); SIP1 (0.801); GAL83 (0.799)

Homologues (species, bitscore): PRKAA2 (Homo sapiens, 218.4); Prkaa1 (Mus musculus, 222.6); prkaa1 (Danio rerio, 222.2); prkaa1 (Xenopus tropicalis, 226.5); AMPKalpha (Drosophila melanogaster, 223.4); aak-2 (Caenorhabditis elegans, 214.2); KIN10 (Arabidopsis thaliana, 220.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:766615-769017:+ gene-YOR233W_AKU4011 rna-NM_001183652.1_AKU4011 cds-NP_014876.1_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000123.1:168658-171060:+ gene-YOR233W_BG1 rna-NM_001183652.1_BG1 cds-NP_014876.1_BG1 99.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:752085-754487:+ gene-YOR233W_Bruggeman rna-NM_001183652.1_Bruggeman cds-NP_014876.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:752736-755138:+ gene-YOR233W_CAT1 rna-NM_001183652.1_CAT1 cds-NP_014876.1_CAT1 99.9 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:749604-752006:+ gene-YOR233W_CBS1585 rna-NM_001183652.1_CBS1585 cds-NP_014876.1_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:748302-750704:+ gene-YOR233W_CBS436 rna-NM_001183652.1_CBS436 cds-NP_014876.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:746723-749125:+ gene-YOR233W_CBS6412 rna-NM_001183652.1_CBS6412 cds-NP_014876.1_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:755363-757765:+ gene-YOR233W_CBS6413 rna-NM_001183652.1_CBS6413 cds-NP_014876.1_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:775608-778010:+ gene-YOR233W_CENPK1137D rna-NM_001183652.1_CENPK1137D cds-NP_014876.1_CENPK1137D 99.9 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:742735-745137:+ gene-YOR233W_EthanolRed rna-NM_001183652.1_EthanolRed cds-NP_014876.1_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:748134-750536:+ gene-YOR233W_FaliES1 rna-NM_001183652.1_FaliES1 cds-NP_014876.1_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000381.1:76298-78700:- gene-YOR233W_JAY291 rna-NM_001183652.1_JAY291 cds-NP_014876.1_JAY291 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:755408-757810:+ gene-YOR233W_MUCL30387 rna-NM_001183652.1_MUCL30387 cds-NP_014876.1_MUCL30387 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:763474-765876:+ gene-YOR233W_MUCL30388 rna-NM_001183652.1_MUCL30388 cds-NP_014876.1_MUCL30388 99.9 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:756934-759336:+ gene-YOR233W_MUCL39482 rna-NM_001183652.1_MUCL39482 cds-NP_014876.1_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:766526-768928:+ gene-YOR233W_MUCL42920 rna-NM_001183652.1_MUCL42920 cds-NP_014876.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:775735-778137:+ gene-YOR233W_NCIM3186 rna-NM_001183652.1_NCIM3186 cds-NP_014876.1_NCIM3186 99.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:757033-759435:+ gene-YOR233W_NCYC1407 rna-NM_001183652.1_NCYC1407 cds-NP_014876.1_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:756338-758740:+ gene-YOR233W_PE2H3 rna-NM_001183652.1_PE2H3 cds-NP_014876.1_PE2H3 99.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:766715-769117:+ gene-YOR233W_PE2H4 rna-NM_001183652.1_PE2H4 cds-NP_014876.1_PE2H4 99.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:775846-778248:+ gene-YOR233W_S288C rna-NM_001183652.1_S288C cds-NP_014876.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000006.1:185839-188241:+ gene-YOR233W_SA1 rna-NM_001183652.1_SA1 cds-NP_014876.1_SA1 99.9 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:747317-749719:+ gene-YOR233W_ThermosaccDry rna-NM_001183652.1_ThermosaccDry cds-NP_014876.1_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:810778-813180:+ gene-YOR233W_VR1 rna-NM_001183652.1_VR1 cds-NP_014876.1_VR1 99.9 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:480238-482640:+ gene-YOR233W_ZTW1 rna-NM_001183652.1_ZTW1 cds-NP_014876.1_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:753187-755616:+ gene-YOR233W_Sparadoxus rna-NM_001183652.1_Sparadoxus cds-NP_014876.1_Sparadoxus 86.0 99.3 Verified 1 1 1 False True False False False

Additional files