Gene name: KIN3
Reference locus (S288C): YAR018C
Gene biotype: protein_coding
Description: Nima (never in mitosis gene a)-related kinase 2; Serine/threonine-protein kinase KIN3; Nonessential serine/threonine protein kinase; possible role in DNA damage response; influences tolerance to high levels of ethanol
Top 10 interactors (score): FUN26 (0.71); SSZ1 (0.678); ZUO1 (0.673); PIR3 (0.61); SWI5 (0.603); ADE1 (0.593); ASC1 (0.591); IPL1 (0.583); CDC14 (0.58); SRM1 (0.562); FMP25 (0.561); ATS1 (0.561); FAR8 (0.56); ERV25 (0.53); SMC3 (0.528); ASE1 (0.525); CAK1 (0.517); CDC27 (0.506); MCK1 (0.502); KIP1 (0.485)
Homologues (species, bitscore): NEK2 (Homo sapiens, 221.5); Nek2 (Mus musculus, 221.5); nek2 (Danio rerio, 212.6); nek2 (Xenopus tropicalis, 157.9); Nek2 (Drosophila melanogaster, 189.5); nekl-3 (Caenorhabditis elegans, 136.3); NEK5 (Arabidopsis thaliana, 152.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005295.1:149895-151202:- | gene-YAR018C_AKU4011 | rna-NM_001178217.1_AKU4011 | cds-NP_009410.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000193.1:4556-5863:- | gene-YAR018C_BG1 | rna-NM_001178217.1_BG1 | cds-NP_009410.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005503.1:165910-167217:- | gene-YAR018C_Bruggeman | rna-NM_001178217.1_Bruggeman | cds-NP_009410.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005519.1:151533-152840:- | gene-YAR018C_CAT1 | rna-NM_001178217.1_CAT1 | cds-NP_009410.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005359.1:162593-163900:- | gene-YAR018C_CBS1585 | rna-NM_001178217.1_CBS1585 | cds-NP_009410.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005343.1:162919-164226:- | gene-YAR018C_CBS436 | rna-NM_001178217.1_CBS436 | cds-NP_009410.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:775335-776642:- | gene-YAR018C_CBS6412 | rna-NM_001178217.1_CBS6412 | cds-NP_009410.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005311.1:160859-162166:- | gene-YAR018C_CBS6413 | rna-NM_001178217.1_CBS6413 | cds-NP_009410.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001522.1:164372-165679:- | gene-YAR018C_CENPK1137D | rna-NM_001178217.1_CENPK1137D | cds-NP_009410.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005471.1:150449-151756:- | gene-YAR018C_EthanolRed | rna-NM_001178217.1_EthanolRed | cds-NP_009410.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005535.1:166110-167417:- | gene-YAR018C_FaliES1 | rna-NM_001178217.1_FaliES1 | cds-NP_009410.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000304.1:4247-5554:- | gene-YAR018C_JAY291 | rna-NM_001178217.1_JAY291 | cds-NP_009410.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005407.1:166446-167753:- | gene-YAR018C_MUCL30387 | rna-NM_001178217.1_MUCL30387 | cds-NP_009410.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005439.1:163100-164407:- | gene-YAR018C_MUCL30388 | rna-NM_001178217.1_MUCL30388 | cds-NP_009410.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005279.1:161847-163154:- | gene-YAR018C_MUCL39482 | rna-NM_001178217.1_MUCL39482 | cds-NP_009410.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005423.1:164248-165555:- | gene-YAR018C_MUCL42920 | rna-NM_001178217.1_MUCL42920 | cds-NP_009410.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011810.1:170273-171580:- | gene-YAR018C_NCIM3186 | rna-NM_001178217.1_NCIM3186 | cds-NP_009410.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005263.1:149259-150566:- | gene-YAR018C_NCYC1407 | rna-NM_001178217.1_NCYC1407 | cds-NP_009410.1_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994140.1:157448-158755:- | gene-YAR018C_PE2H3 | rna-NM_001178217.1_PE2H3 | cds-NP_009410.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999872.1:157167-158474:- | gene-YAR018C_PE2H4 | rna-NM_001178217.1_PE2H4 | cds-NP_009410.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001133.9:170396-171703:- | gene-YAR018C_S288C | rna-NM_001178217.1_S288C | cds-NP_009410.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000100.1:23198-24505:- | gene-YAR018C_SA1 | rna-NM_001178217.1_SA1 | cds-NP_009410.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005487.1:165115-166422:- | gene-YAR018C_ThermosaccDry | rna-NM_001178217.1_ThermosaccDry | cds-NP_009410.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005455.1:169671-170978:- | gene-YAR018C_VR1 | rna-NM_001178217.1_VR1 | cds-NP_009410.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000002.1:136938-138245:- | gene-YAR018C_ZTW1 | rna-NM_001178217.1_ZTW1 | cds-NP_009410.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047487.1:154601-155908:- | gene-YAR018C_Sparadoxus | rna-NM_001178217.1_Sparadoxus | cds-NP_009410.1_Sparadoxus | 92.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |