Gene name: KIN28
Reference locus (S288C): YDL108W
Gene biotype: protein_coding
Description: Serine/threonine-protein kinase KIN28; Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia
Top 10 interactors (score): TFA2 (0.999); TFB4 (0.999); SSL1 (0.999); TFB3 (0.999); CCL1 (0.999); TFB1 (0.999); TFB5 (0.999); RPO21 (0.999); TFB2 (0.999); RAD3 (0.999); TFA1 (0.999); SSL2 (0.999); CTK2 (0.996); CDC28 (0.994); SSN8 (0.991); SUA7 (0.991); CAK1 (0.989); SPT5 (0.985); SPT15 (0.98); CLB2 (0.975)
Homologues (species, bitscore): CDK7 (Homo sapiens, 290.4); Cdk7 (Mus musculus, 292.4); cdk7 (Danio rerio, 292.7); cdk7 (Xenopus tropicalis, 297.0); Cdk7 (Drosophila melanogaster, 284.6); cdk-7 (Caenorhabditis elegans, 257.3); CDKD1;3 (Arabidopsis thaliana, 306.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:252323-253324:+ | gene-YDL108W_AKU4011 | rna-NM_001180167.1_AKU4011 | cds-NP_010175.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:296626-297627:- | gene-YDL108W_BG1 | rna-NM_001180167.1_BG1 | cds-NP_010175.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:269735-270736:+ | gene-YDL108W_Bruggeman | rna-NM_001180167.1_Bruggeman | cds-NP_010175.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:266475-267476:+ | gene-YDL108W_CAT1 | rna-NM_001180167.1_CAT1 | cds-NP_010175.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:250583-251584:+ | gene-YDL108W_CBS1585 | rna-NM_001180167.1_CBS1585 | cds-NP_010175.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:267244-268245:+ | gene-YDL108W_CBS436 | rna-NM_001180167.1_CBS436 | cds-NP_010175.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:249009-250010:+ | gene-YDL108W_CBS6412 | rna-NM_001180167.1_CBS6412 | cds-NP_010175.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:268744-269745:+ | gene-YDL108W_CBS6413 | rna-NM_001180167.1_CBS6413 | cds-NP_010175.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:266471-267472:+ | gene-YDL108W_CENPK1137D | rna-NM_001180167.1_CENPK1137D | cds-NP_010175.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:263350-264351:+ | gene-YDL108W_EthanolRed | rna-NM_001180167.1_EthanolRed | cds-NP_010175.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:269320-270321:+ | gene-YDL108W_FaliES1 | rna-NM_001180167.1_FaliES1 | cds-NP_010175.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000010.1:39364-40365:+ | gene-YDL108W_JAY291 | rna-NM_001180167.1_JAY291 | cds-NP_010175.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:267522-268523:+ | gene-YDL108W_MUCL30387 | rna-NM_001180167.1_MUCL30387 | cds-NP_010175.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:258280-259281:+ | gene-YDL108W_MUCL30388 | rna-NM_001180167.1_MUCL30388 | cds-NP_010175.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:251689-252690:+ | gene-YDL108W_MUCL39482 | rna-NM_001180167.1_MUCL39482 | cds-NP_010175.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:173474-174475:+ | gene-YDL108W_MUCL42920 | rna-NM_001180167.1_MUCL42920 | cds-NP_010175.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:267621-268622:+ | gene-YDL108W_NCIM3186 | rna-NM_001180167.1_NCIM3186 | cds-NP_010175.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:251717-252718:+ | gene-YDL108W_NCYC1407 | rna-NM_001180167.1_NCYC1407 | cds-NP_010175.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:258475-259476:+ | gene-YDL108W_PE2H3 | rna-NM_001180167.1_PE2H3 | cds-NP_010175.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:258479-259480:+ | gene-YDL108W_PE2H4 | rna-NM_001180167.1_PE2H4 | cds-NP_010175.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:267698-268699:+ | gene-YDL108W_S288C | rna-NM_001180167.1_S288C | cds-NP_010175.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000010.1:166215-167216:- | gene-YDL108W_SA1 | rna-NM_001180167.1_SA1 | cds-NP_010175.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:268831-269832:+ | gene-YDL108W_ThermosaccDry | rna-NM_001180167.1_ThermosaccDry | cds-NP_010175.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:270937-271938:+ | gene-YDL108W_VR1 | rna-NM_001180167.1_VR1 | cds-NP_010175.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:266756-267757:+ | gene-YDL108W_ZTW1 | rna-NM_001180167.1_ZTW1 | cds-NP_010175.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:268907-269912:+ | gene-YDL108W_Sparadoxus | rna-NM_001180167.1_Sparadoxus | cds-NP_010175.1_Sparadoxus | 91.1 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |