Gene name: KGD2
Reference locus (S288C): YDR148C
Gene biotype: protein_coding
Description: Dihydrolipoyl transsuccinylase; component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes the oxidative decarboxylation of alpha-ketoglutarate to succinyl-CoA in the TCA cycle; phosphorylated
Top 10 interactors (score): LPD1 (0.999); LSC2 (0.999); LSC1 (0.999); KGD1 (0.999); ATP16 (0.998); LAT1 (0.997); GCV3 (0.995); PDX1 (0.995); IDH2 (0.994); SDH2 (0.993); YMR31 (0.993); PDB1 (0.992); IDH1 (0.988); FUM1 (0.988); ACO1 (0.986); IRC15 (0.984); MDH1 (0.983); SDH4 (0.979); AIM22 (0.978); RIP1 (0.967)
Homologues (species, bitscore): DLST (Homo sapiens, 351.3); Dlst (Mus musculus, 355.9); dlst (Danio rerio, 362.1); dlst (Xenopus tropicalis, 355.9); CG5214 (Drosophila melanogaster, 374.4); dlst-1 (Caenorhabditis elegans, 361.7); AT4G26910 (Arabidopsis thaliana, 344.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:724626-726017:- | gene-YDR148C_AKU4011 | rna-NM_001180455.3_AKU4011 | cds-NP_010432.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:398853-400244:+ | gene-YDR148C_BG1 | rna-NM_001180455.3_BG1 | cds-NP_010432.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:756694-758085:- | gene-YDR148C_Bruggeman | rna-NM_001180455.3_Bruggeman | cds-NP_010432.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:744671-746062:- | gene-YDR148C_CAT1 | rna-NM_001180455.3_CAT1 | cds-NP_010432.3_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:715658-717049:- | gene-YDR148C_CBS1585 | rna-NM_001180455.3_CBS1585 | cds-NP_010432.3_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:741536-742927:- | gene-YDR148C_CBS436 | rna-NM_001180455.3_CBS436 | cds-NP_010432.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:711998-713389:- | gene-YDR148C_CBS6412 | rna-NM_001180455.3_CBS6412 | cds-NP_010432.3_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:740994-742385:- | gene-YDR148C_CBS6413 | rna-NM_001180455.3_CBS6413 | cds-NP_010432.3_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:746125-747516:- | gene-YDR148C_CENPK1137D | rna-NM_001180455.3_CENPK1137D | cds-NP_010432.3_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:726383-727774:- | gene-YDR148C_EthanolRed | rna-NM_001180455.3_EthanolRed | cds-NP_010432.3_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:733177-734568:- | gene-YDR148C_FaliES1 | rna-NM_001180455.3_FaliES1 | cds-NP_010432.3_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000002.1:85306-86697:- | gene-YDR148C_JAY291 | rna-NM_001180455.3_JAY291 | cds-NP_010432.3_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:742618-744009:- | gene-YDR148C_MUCL30387 | rna-NM_001180455.3_MUCL30387 | cds-NP_010432.3_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:731637-733028:- | gene-YDR148C_MUCL30388 | rna-NM_001180455.3_MUCL30388 | cds-NP_010432.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:716997-718388:- | gene-YDR148C_MUCL39482 | rna-NM_001180455.3_MUCL39482 | cds-NP_010432.3_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:654980-656371:- | gene-YDR148C_MUCL42920 | rna-NM_001180455.3_MUCL42920 | cds-NP_010432.3_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:753598-754989:- | gene-YDR148C_NCIM3186 | rna-NM_001180455.3_NCIM3186 | cds-NP_010432.3_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:716402-717793:- | gene-YDR148C_NCYC1407 | rna-NM_001180455.3_NCYC1407 | cds-NP_010432.3_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:735747-737138:- | gene-YDR148C_PE2H3 | rna-NM_001180455.3_PE2H3 | cds-NP_010432.3_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:735052-736443:- | gene-YDR148C_PE2H4 | rna-NM_001180455.3_PE2H4 | cds-NP_010432.3_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:753675-755066:- | gene-YDR148C_S288C | rna-NM_001180455.3_S288C | cds-NP_010432.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000009.1:102363-103754:- | gene-YDR148C_SA1 | rna-NM_001180455.3_SA1 | cds-NP_010432.3_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:732699-734090:- | gene-YDR148C_ThermosaccDry | rna-NM_001180455.3_ThermosaccDry | cds-NP_010432.3_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:746285-747676:- | gene-YDR148C_VR1 | rna-NM_001180455.3_VR1 | cds-NP_010432.3_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:730314-731705:- | gene-YDR148C_ZTW1 | rna-NM_001180455.3_ZTW1 | cds-NP_010432.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:734917-736290:- | gene-YDR148C_Sparadoxus | rna-NM_001180455.3_Sparadoxus | cds-NP_010432.3_Sparadoxus | 87.9 | 98.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |