Gene name: KGD1
Reference locus (S288C): YIL125W
Gene biotype: protein_coding
Description: 2-oxoglutarate dehydrogenase, mitochondrial; Subunit of the mitochondrial alpha-ketoglutarate dehydrogenase complex; catalyzes a key step in the tricarboxylic acid (TCA) cycle, the oxidative decarboxylation of alpha-ketoglutarate to form succinyl-CoA
Top 10 interactors (score): KGD2 (0.999); LSC1 (0.999); YMR31 (0.999); LPD1 (0.999); FUM1 (0.998); IDH2 (0.998); IDH1 (0.998); LSC2 (0.998); ACO1 (0.996); SDH2 (0.994); PDA1 (0.993); ATP1 (0.991); IDP1 (0.983); LAT1 (0.983); MDH1 (0.982); IDP2 (0.976); CDC60 (0.975); CIT1 (0.973); PDB1 (0.97); IDP3 (0.969)
Homologues (species, bitscore): OGDH (Homo sapiens, 862.4); Ogdh (Mus musculus, 859.4); ogdhb (Danio rerio, 875.2); ogdh (Xenopus tropicalis, 873.2); Nc73EF (Drosophila melanogaster, 868.2); ogdh-1 (Caenorhabditis elegans, 867.8); AT5G65750 (Arabidopsis thaliana, 972.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:123906-126950:+ | gene-YIL125W_AKU4011 | rna-NM_001179473.1_AKU4011 | cds-NP_012141.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000174.1:10809-13853:- | gene-YIL125W_BG1 | rna-NM_001179473.1_BG1 | cds-NP_012141.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:126656-129700:+ | gene-YIL125W_Bruggeman | rna-NM_001179473.1_Bruggeman | cds-NP_012141.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:120536-123580:+ | gene-YIL125W_CAT1 | rna-NM_001179473.1_CAT1 | cds-NP_012141.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:124137-127181:+ | gene-YIL125W_CBS1585 | rna-NM_001179473.1_CBS1585 | cds-NP_012141.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:115275-118319:+ | gene-YIL125W_CBS436 | rna-NM_001179473.1_CBS436 | cds-NP_012141.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005335.1:121625-124669:+ | gene-YIL125W_CBS6412 | rna-NM_001179473.1_CBS6412 | cds-NP_012141.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:115385-118429:+ | gene-YIL125W_CBS6413 | rna-NM_001179473.1_CBS6413 | cds-NP_012141.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:114394-117438:+ | gene-YIL125W_CENPK1137D | rna-NM_001179473.1_CENPK1137D | cds-NP_012141.1_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:109190-112234:+ | gene-YIL125W_EthanolRed | rna-NM_001179473.1_EthanolRed | cds-NP_012141.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:125241-128285:+ | gene-YIL125W_FaliES1 | rna-NM_001179473.1_FaliES1 | cds-NP_012141.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000383.1:21048-24092:- | gene-YIL125W_JAY291 | rna-NM_001179473.1_JAY291 | cds-NP_012141.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:124511-127555:+ | gene-YIL125W_MUCL30387 | rna-NM_001179473.1_MUCL30387 | cds-NP_012141.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:124095-127139:+ | gene-YIL125W_MUCL30388 | rna-NM_001179473.1_MUCL30388 | cds-NP_012141.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:125083-128127:+ | gene-YIL125W_MUCL39482 | rna-NM_001179473.1_MUCL39482 | cds-NP_012141.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:128269-131313:+ | gene-YIL125W_MUCL42920 | rna-NM_001179473.1_MUCL42920 | cds-NP_012141.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:122689-125733:+ | gene-YIL125W_NCIM3186 | rna-NM_001179473.1_NCIM3186 | cds-NP_012141.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:129069-132113:+ | gene-YIL125W_NCYC1407 | rna-NM_001179473.1_NCYC1407 | cds-NP_012141.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:123749-126793:+ | gene-YIL125W_PE2H3 | rna-NM_001179473.1_PE2H3 | cds-NP_012141.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:117724-120768:+ | gene-YIL125W_PE2H4 | rna-NM_001179473.1_PE2H4 | cds-NP_012141.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:122689-125733:+ | gene-YIL125W_S288C | rna-NM_001179473.1_S288C | cds-NP_012141.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000058.1:57527-60571:- | gene-YIL125W_SA1 | rna-NM_001179473.1_SA1 | cds-NP_012141.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:123898-126942:+ | gene-YIL125W_ThermosaccDry | rna-NM_001179473.1_ThermosaccDry | cds-NP_012141.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:121058-124102:+ | gene-YIL125W_VR1 | rna-NM_001179473.1_VR1 | cds-NP_012141.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000019.1:98834-101878:+ | gene-YIL125W_ZTW1 | rna-NM_001179473.1_ZTW1 | cds-NP_012141.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:116629-119673:+ | gene-YIL125W_Sparadoxus | rna-NM_001179473.1_Sparadoxus | cds-NP_012141.1_Sparadoxus | 90.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |