Gene name: KEX2
Reference locus (S288C): YNL238W
Gene biotype: protein_coding
Description: Kexin, a subtilisin-like protease (proprotein convertase); a calcium-dependent serine protease involved in the activation of proproteins of the secretory pathway; Belongs to the peptidase S8 family. Furin subfamily
Top 10 interactors (score): KEX1 (0.999); YPS1 (0.986); EST2 (0.978); STE13 (0.973); KAR2 (0.957); SEC61 (0.952); PEP1 (0.94); ERD2 (0.935); PEP4 (0.917); PRC1 (0.915); MKC7 (0.914); SEC7 (0.897); VPS13 (0.894); VPS27 (0.891); LHS1 (0.89); HUT1 (0.889); SEC63 (0.888); CHC1 (0.878); SBH2 (0.878); PDI1 (0.864)
Homologues (species, bitscore): PCSK7 (Homo sapiens, 389.4); Pcsk7 (Mus musculus, 391.0); pcsk7 (Danio rerio, 399.8); pcsk7 (Xenopus tropicalis, 382.9); Fur2 (Drosophila melanogaster, 345.9); kpc-1 (Caenorhabditis elegans, 347.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:196207-198651:+ | gene-YNL238W_AKU4011 | rna-NM_001183076.1_AKU4011 | cds-NP_014161.1_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:100150-102594:+ | gene-YNL238W_BG1 | rna-NM_001183076.1_BG1 | cds-NP_014161.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:206009-208702:+ | gene-YNL238W_Bruggeman | rna-NM_001183076.1_Bruggeman | cds-NP_014161.1_Bruggeman | 89.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:213309-215753:+ | gene-YNL238W_CAT1 | rna-NM_001183076.1_CAT1 | cds-NP_014161.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:196604-199048:+ | gene-YNL238W_CBS1585 | rna-NM_001183076.1_CBS1585 | cds-NP_014161.1_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:191692-194136:+ | gene-YNL238W_CBS436 | rna-NM_001183076.1_CBS436 | cds-NP_014161.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:192638-195082:+ | gene-YNL238W_CBS6412 | rna-NM_001183076.1_CBS6412 | cds-NP_014161.1_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:193286-195730:+ | gene-YNL238W_CBS6413 | rna-NM_001183076.1_CBS6413 | cds-NP_014161.1_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:196239-198683:+ | gene-YNL238W_CENPK1137D | rna-NM_001183076.1_CENPK1137D | cds-NP_014161.1_CENPK1137D | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:193856-196300:+ | gene-YNL238W_EthanolRed | rna-NM_001183076.1_EthanolRed | cds-NP_014161.1_EthanolRed | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:188598-191042:+ | gene-YNL238W_FaliES1 | rna-NM_001183076.1_FaliES1 | cds-NP_014161.1_FaliES1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000082.1:99741-102185:+ | gene-YNL238W_JAY291 | rna-NM_001183076.1_JAY291 | cds-NP_014161.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:201792-204236:+ | gene-YNL238W_MUCL30387 | rna-NM_001183076.1_MUCL30387 | cds-NP_014161.1_MUCL30387 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:200377-202821:+ | gene-YNL238W_MUCL30388 | rna-NM_001183076.1_MUCL30388 | cds-NP_014161.1_MUCL30388 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:194094-196538:+ | gene-YNL238W_MUCL39482 | rna-NM_001183076.1_MUCL39482 | cds-NP_014161.1_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:196349-198793:+ | gene-YNL238W_MUCL42920 | rna-NM_001183076.1_MUCL42920 | cds-NP_014161.1_MUCL42920 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:202397-204841:+ | gene-YNL238W_NCIM3186 | rna-NM_001183076.1_NCIM3186 | cds-NP_014161.1_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:196184-198628:+ | gene-YNL238W_NCYC1407 | rna-NM_001183076.1_NCYC1407 | cds-NP_014161.1_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:193084-195528:+ | gene-YNL238W_PE2H3 | rna-NM_001183076.1_PE2H3 | cds-NP_014161.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:192472-194916:+ | gene-YNL238W_PE2H4 | rna-NM_001183076.1_PE2H4 | cds-NP_014161.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:202428-204872:+ | gene-YNL238W_S288C | rna-NM_001183076.1_S288C | cds-NP_014161.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000040.1:47429-49873:- | gene-YNL238W_SA1 | rna-NM_001183076.1_SA1 | cds-NP_014161.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:189454-191898:+ | gene-YNL238W_ThermosaccDry | rna-NM_001183076.1_ThermosaccDry | cds-NP_014161.1_ThermosaccDry | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:208342-210786:+ | gene-YNL238W_VR1 | rna-NM_001183076.1_VR1 | cds-NP_014161.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:99773-102217:+ | gene-YNL238W_ZTW1 | rna-NM_001183076.1_ZTW1 | cds-NP_014161.1_ZTW1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:199782-202226:+ | gene-YNL238W_Sparadoxus | rna-NM_001183076.1_Sparadoxus | cds-NP_014161.1_Sparadoxus | 88.5 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |