Gene name: KEX1
Reference locus (S288C): YGL203C
Gene biotype: protein_coding
Description: Pheromone-processing carboxypeptidase KEX1; Cell death protease essential for hypochlorite-induced apoptosis; involved in the processing of killer toxin and alpha factor precursor; cleaves Lys and Arg residues from the C-terminus of peptides and proteins
Top 10 interactors (score): KEX2 (0.999); STE13 (0.931); KRE1 (0.894); NMA111 (0.862); BXI1 (0.843); ERD2 (0.84); RCE1 (0.787); MCA1 (0.776); OST3 (0.776); STE23 (0.761); STE14 (0.759); MKC7 (0.749); BST1 (0.734); PEP4 (0.691); YPS1 (0.688); ALG8 (0.688); PEP1 (0.67); STE24 (0.665); MF(ALPHA)2 (0.62); MF(ALPHA)1 (0.616)
Homologues (species, bitscore): CTSA (Homo sapiens, 139.8); Ctsa (Mus musculus, 131.3); cpvl (Danio rerio, 133.7); cpvl (Xenopus tropicalis, 139.0); CG31823 (Drosophila melanogaster, 116.3); K10B2.2 (Caenorhabditis elegans, 127.9); scpl47 (Arabidopsis thaliana, 177.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:114007-116220:- | gene-YGL203C_AKU4011 | rna-NM_001181068.1_AKU4011 | cds-NP_011312.1_AKU4011 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000175.1:106303-108516:- | gene-YGL203C_BG1 | rna-NM_001181068.1_BG1 | cds-NP_011312.1_BG1 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:116028-118241:- | gene-YGL203C_Bruggeman | rna-NM_001181068.1_Bruggeman | cds-NP_011312.1_Bruggeman | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:112414-114627:- | gene-YGL203C_CAT1 | rna-NM_001181068.1_CAT1 | cds-NP_011312.1_CAT1 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:118131-120344:- | gene-YGL203C_CBS1585 | rna-NM_001181068.1_CBS1585 | cds-NP_011312.1_CBS1585 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:113113-115326:- | gene-YGL203C_CBS436 | rna-NM_001181068.1_CBS436 | cds-NP_011312.1_CBS436 | 98.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:104900-107113:- | gene-YGL203C_CBS6412 | rna-NM_001181068.1_CBS6412 | cds-NP_011312.1_CBS6412 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:112435-114648:- | gene-YGL203C_CBS6413 | rna-NM_001181068.1_CBS6413 | cds-NP_011312.1_CBS6413 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:112507-114720:- | gene-YGL203C_CENPK1137D | rna-NM_001181068.1_CENPK1137D | cds-NP_011312.1_CENPK1137D | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:104631-106844:- | gene-YGL203C_EthanolRed | rna-NM_001181068.1_EthanolRed | cds-NP_011312.1_EthanolRed | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:105474-107687:- | gene-YGL203C_FaliES1 | rna-NM_001181068.1_FaliES1 | cds-NP_011312.1_FaliES1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000397.1:31291-33504:- | gene-YGL203C_JAY291 | rna-NM_001181068.1_JAY291 | cds-NP_011312.1_JAY291 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:114245-116434:- | gene-YGL203C_MUCL30387 | rna-NM_001181068.1_MUCL30387 | cds-NP_011312.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:116575-118764:- | gene-YGL203C_MUCL30388 | rna-NM_001181068.1_MUCL30388 | cds-NP_011312.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:114644-116857:- | gene-YGL203C_MUCL39482 | rna-NM_001181068.1_MUCL39482 | cds-NP_011312.1_MUCL39482 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:117749-119962:- | gene-YGL203C_MUCL42920 | rna-NM_001181068.1_MUCL42920 | cds-NP_011312.1_MUCL42920 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:112475-114664:- | gene-YGL203C_NCIM3186 | rna-NM_001181068.1_NCIM3186 | cds-NP_011312.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:106366-108828:- | gene-YGL203C_NCYC1407 | rna-NM_001181068.1_NCYC1407 | cds-NP_011312.1_NCYC1407 | 88.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:108609-110822:- | gene-YGL203C_PE2H3 | rna-NM_001181068.1_PE2H3 | cds-NP_011312.1_PE2H3 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:108157-110370:- | gene-YGL203C_PE2H4 | rna-NM_001181068.1_PE2H4 | cds-NP_011312.1_PE2H4 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:112475-114664:- | gene-YGL203C_S288C | rna-NM_001181068.1_S288C | cds-NP_011312.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:261173-263386:+ | gene-YGL203C_SA1 | rna-NM_001181068.1_SA1 | cds-NP_011312.1_SA1 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:105735-107948:- | gene-YGL203C_ThermosaccDry | rna-NM_001181068.1_ThermosaccDry | cds-NP_011312.1_ThermosaccDry | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:113024-115237:- | gene-YGL203C_VR1 | rna-NM_001181068.1_VR1 | cds-NP_011312.1_VR1 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:104771-106984:- | gene-YGL203C_ZTW1 | rna-NM_001181068.1_ZTW1 | cds-NP_011312.1_ZTW1 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:118776-120950:+ | gene-YGL203C_Sparadoxus | rna-NM_001181068.1_Sparadoxus | cds-NP_011312.1_Sparadoxus | 87.0 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |