Gene name: KES1
Reference locus (S288C): YPL145C
Gene biotype: protein_coding
Description: Oxysterol-binding protein homolog 4; One of seven members of the yeast oxysterol binding protein family; involved in negative regulation of Sec14p-dependent Golgi complex secretory functions, peripheral membrane protein that localizes to the Golgi complex; KES1 has a paralog, HES1, that arose from the whole genome duplication; Belongs to the OSBP family
Top 10 interactors (score): SEC14 (0.995); OSH3 (0.976); SAC1 (0.944); PIK1 (0.937); DRS2 (0.901); SEC4 (0.896); SPO14 (0.87); PRY1 (0.847); STT4 (0.817); PRY2 (0.813); OSH2 (0.788); SCS2 (0.783); SWH1 (0.762); OSH7 (0.75); MSS4 (0.743); CDC42 (0.697); YOR282W (0.69); CDC50 (0.683); CAB4 (0.681); YPT31 (0.679)
Homologues (species, bitscore): OSBPL9 (Homo sapiens, 139.8); Osbpl9 (Mus musculus, 140.2); osbpl9 (Danio rerio, 130.6); osbpl9 (Xenopus tropicalis, 143.3); CG1513 (Drosophila melanogaster, 143.3); obr-4 (Caenorhabditis elegans, 113.2); ORP4C (Arabidopsis thaliana, 72.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:256050-257354:- | gene-YPL145C_AKU4011 | rna-NM_001183959.1_AKU4011 | cds-NP_015180.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:461736-463040:- | gene-YPL145C_BG1 | rna-NM_001183959.1_BG1 | cds-NP_015180.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:282046-283350:- | gene-YPL145C_Bruggeman | rna-NM_001183959.1_Bruggeman | cds-NP_015180.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:278723-280027:- | gene-YPL145C_CAT1 | rna-NM_001183959.1_CAT1 | cds-NP_015180.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:260116-261420:- | gene-YPL145C_CBS1585 | rna-NM_001183959.1_CBS1585 | cds-NP_015180.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:274790-276094:- | gene-YPL145C_CBS436 | rna-NM_001183959.1_CBS436 | cds-NP_015180.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:264791-266095:- | gene-YPL145C_CBS6412 | rna-NM_001183959.1_CBS6412 | cds-NP_015180.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:256755-258059:- | gene-YPL145C_CBS6413 | rna-NM_001183959.1_CBS6413 | cds-NP_015180.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:278297-279601:- | gene-YPL145C_CENPK1137D | rna-NM_001183959.1_CENPK1137D | cds-NP_015180.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:254740-256044:- | gene-YPL145C_EthanolRed | rna-NM_001183959.1_EthanolRed | cds-NP_015180.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:262332-263636:- | gene-YPL145C_FaliES1 | rna-NM_001183959.1_FaliES1 | cds-NP_015180.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000007.1:102217-103521:+ | gene-YPL145C_JAY291 | rna-NM_001183959.1_JAY291 | cds-NP_015180.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:273289-274593:- | gene-YPL145C_MUCL30387 | rna-NM_001183959.1_MUCL30387 | cds-NP_015180.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:271303-272607:- | gene-YPL145C_MUCL30388 | rna-NM_001183959.1_MUCL30388 | cds-NP_015180.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:253445-254749:- | gene-YPL145C_MUCL39482 | rna-NM_001183959.1_MUCL39482 | cds-NP_015180.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:310686-311990:- | gene-YPL145C_MUCL42920 | rna-NM_001183959.1_MUCL42920 | cds-NP_015180.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:278378-279682:- | gene-YPL145C_NCIM3186 | rna-NM_001183959.1_NCIM3186 | cds-NP_015180.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:259905-261209:- | gene-YPL145C_NCYC1407 | rna-NM_001183959.1_NCYC1407 | cds-NP_015180.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:267352-268656:- | gene-YPL145C_PE2H3 | rna-NM_001183959.1_PE2H3 | cds-NP_015180.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:266981-268285:- | gene-YPL145C_PE2H4 | rna-NM_001183959.1_PE2H4 | cds-NP_015180.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:278395-279699:- | gene-YPL145C_S288C | rna-NM_001183959.1_S288C | cds-NP_015180.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000012.1:93988-95292:+ | gene-YPL145C_SA1 | rna-NM_001183959.1_SA1 | cds-NP_015180.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:262130-263434:- | gene-YPL145C_ThermosaccDry | rna-NM_001183959.1_ThermosaccDry | cds-NP_015180.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:277107-278411:- | gene-YPL145C_VR1 | rna-NM_001183959.1_VR1 | cds-NP_015180.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:261461-262765:- | gene-YPL145C_ZTW1 | rna-NM_001183959.1_ZTW1 | cds-NP_015180.1_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:263124-264428:- | gene-YPL145C_Sparadoxus | rna-NM_001183959.1_Sparadoxus | cds-NP_015180.1_Sparadoxus | 92.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |