KEL2 (YGR238C)


Gene profile

Gene name: KEL2
Reference locus (S288C): YGR238C
Gene biotype: protein_coding

Description: Kelch repeat-containing protein 2; Protein that negatively regulates mitotic exit; forms a complex with Kel1p and Bud14p that regulates Bnr1p (formin) to affect actin cable assembly, cytokinesis, and polarized growth; functions in a complex with Kel1p, interacts with Tem1p and Lte1p; localizes to regions of polarized growth; potential Cdc28p substrate

Top 10 interactors (score): KEL1 (0.999); BUD14 (0.999); BIK1 (0.972); LTE1 (0.906); BNI1 (0.888); BUD6 (0.83); PUF3 (0.801); KIP2 (0.737); TEM1 (0.725); BNR1 (0.721); OPY1 (0.694); CDC42 (0.644); EPO1 (0.628); FUS1 (0.618); STU2 (0.615); KIN2 (0.599); KIN1 (0.589); FRK1 (0.559); AIM10 (0.53); MSB4 (0.529)

Homologues (species, bitscore): RABEPK (Homo sapiens, 103.6); Hcfc1 (Mus musculus, 93.2); rabepk (Danio rerio, 97.1); rabepk (Xenopus tropicalis, 104.4); Hcf (Drosophila melanogaster, 96.7); hcf-1 (Caenorhabditis elegans, 83.6); AT1G18610 (Arabidopsis thaliana, 104.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:931446-934094:- gene-YGR238C_AKU4011 rna-NM_001181367.3_AKU4011 cds-NP_011754.3_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000021.1:211552-214200:- gene-YGR238C_BG1 rna-NM_001181367.3_BG1 cds-NP_011754.3_BG1 99.5 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:939036-941684:- gene-YGR238C_Bruggeman rna-NM_001181367.3_Bruggeman cds-NP_011754.3_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:938583-941231:- gene-YGR238C_CAT1 rna-NM_001181367.3_CAT1 cds-NP_011754.3_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:934310-936958:- gene-YGR238C_CBS1585 rna-NM_001181367.3_CBS1585 cds-NP_011754.3_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:937959-940607:- gene-YGR238C_CBS436 rna-NM_001181367.3_CBS436 cds-NP_011754.3_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:925188-927836:- gene-YGR238C_CBS6412 rna-NM_001181367.3_CBS6412 cds-NP_011754.3_CBS6412 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:931239-933887:- gene-YGR238C_CBS6413 rna-NM_001181367.3_CBS6413 cds-NP_011754.3_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:965686-968368:- gene-YGR238C_CENPK1137D rna-NM_001181367.3_CENPK1137D cds-NP_011754.3_CENPK1137D 98.0 100.0 Unannotated 1 1 0 False False False True False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:919287-921935:- gene-YGR238C_EthanolRed rna-NM_001181367.3_EthanolRed cds-NP_011754.3_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:924093-926741:- gene-YGR238C_FaliES1 rna-NM_001181367.3_FaliES1 cds-NP_011754.3_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000076.1:103554-106202:+ gene-YGR238C_JAY291 rna-NM_001181367.3_JAY291 cds-NP_011754.3_JAY291 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:936952-939600:- gene-YGR238C_MUCL30387 rna-NM_001181367.3_MUCL30387 cds-NP_011754.3_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:936216-938864:- gene-YGR238C_MUCL30388 rna-NM_001181367.3_MUCL30388 cds-NP_011754.3_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:929436-932084:- gene-YGR238C_MUCL39482 rna-NM_001181367.3_MUCL39482 cds-NP_011754.3_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:947933-950581:- gene-YGR238C_MUCL42920 rna-NM_001181367.3_MUCL42920 cds-NP_011754.3_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:966039-968687:- gene-YGR238C_NCIM3186 rna-NM_001181367.3_NCIM3186 cds-NP_011754.3_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:925050-927698:- gene-YGR238C_NCYC1407 rna-NM_001181367.3_NCYC1407 cds-NP_011754.3_NCYC1407 99.2 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:950230-952878:- gene-YGR238C_PE2H3 rna-NM_001181367.3_PE2H3 cds-NP_011754.3_PE2H3 99.9 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:955069-957717:- gene-YGR238C_PE2H4 rna-NM_001181367.3_PE2H4 cds-NP_011754.3_PE2H4 99.9 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:966039-968687:- gene-YGR238C_S288C rna-NM_001181367.3_S288C cds-NP_011754.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000045.1:32809-35457:+ gene-YGR238C_SA1 rna-NM_001181367.3_SA1 cds-NP_011754.3_SA1 99.9 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:944620-947268:- gene-YGR238C_ThermosaccDry rna-NM_001181367.3_ThermosaccDry cds-NP_011754.3_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:1049879-1052527:- gene-YGR238C_VR1 rna-NM_001181367.3_VR1 cds-NP_011754.3_VR1 99.9 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000016.1:246029-248677:- gene-YGR238C_ZTW1 rna-NM_001181367.3_ZTW1 cds-NP_011754.3_ZTW1 99.2 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:936847-939492:- gene-YGR238C_Sparadoxus rna-NM_001181367.3_Sparadoxus cds-NP_011754.3_Sparadoxus 83.4 99.7 Verified 1 1 0 False False False True False

Additional files