Gene name: KEL1
Reference locus (S288C): YHR158C
Gene biotype: protein_coding
Description: Kelch repeat-containing protein 1; Protein required for proper cell fusion and cell morphology; forms a complex with Bud14p and Kel2p that regulates Bnr1p (formin) to affect actin cable assembly, cytokinesis, and polarized growth; functions in a complex with Kel2p to negatively regulate mitotic exit, interacts with Tem1p and Lte1p; localizes to regions of polarized growth; potential Cdc28p substrate
Top 10 interactors (score): KEL2 (0.999); BUD14 (0.999); LTE1 (0.999); BIK1 (0.97); BNI1 (0.948); TEM1 (0.878); SPA2 (0.875); BUD6 (0.869); CDC42 (0.837); KIP2 (0.807); EPO1 (0.805); KIN1 (0.8); BNR1 (0.772); ACT1 (0.77); KIN4 (0.755); TDA11 (0.745); CLB2 (0.719); FUS2 (0.712); RAS2 (0.699); BFA1 (0.695)
Homologues (species, bitscore): RABEPK (Homo sapiens, 87.0); Hcfc1 (Mus musculus, 87.0); lztr1 (Danio rerio, 90.1); hcfc1 (Xenopus tropicalis, 89.0); Lztr1 (Drosophila melanogaster, 87.4); hcf-1 (Caenorhabditis elegans, 79.7); AT1G18610 (Arabidopsis thaliana, 90.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005302.1:400776-404270:- | gene-YHR158C_AKU4011 | rna-NM_001179289.1_AKU4011 | cds-NP_012028.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000141.1:113451-116945:+ | gene-YHR158C_BG1 | rna-NM_001179289.1_BG1 | cds-NP_012028.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005510.1:408016-411510:- | gene-YHR158C_Bruggeman | rna-NM_001179289.1_Bruggeman | cds-NP_012028.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005526.1:403442-406933:- | gene-YHR158C_CAT1 | rna-NM_001179289.1_CAT1 | cds-NP_012028.1_CAT1 | 99.7 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005366.1:400233-403727:- | gene-YHR158C_CBS1585 | rna-NM_001179289.1_CBS1585 | cds-NP_012028.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005350.1:397695-401189:- | gene-YHR158C_CBS436 | rna-NM_001179289.1_CBS436 | cds-NP_012028.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005334.1:400686-404180:- | gene-YHR158C_CBS6412 | rna-NM_001179289.1_CBS6412 | cds-NP_012028.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005318.1:401113-404607:- | gene-YHR158C_CBS6413 | rna-NM_001179289.1_CBS6413 | cds-NP_012028.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001529.1:406857-410351:- | gene-YHR158C_CENPK1137D | rna-NM_001179289.1_CENPK1137D | cds-NP_012028.1_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:459327-462821:- | gene-YHR158C_EthanolRed | rna-NM_001179289.1_EthanolRed | cds-NP_012028.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005542.1:401770-405264:- | gene-YHR158C_FaliES1 | rna-NM_001179289.1_FaliES1 | cds-NP_012028.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000017.1:34568-38062:+ | gene-YHR158C_JAY291 | rna-NM_001179289.1_JAY291 | cds-NP_012028.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005414.1:409096-412590:- | gene-YHR158C_MUCL30387 | rna-NM_001179289.1_MUCL30387 | cds-NP_012028.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005446.1:408538-412032:- | gene-YHR158C_MUCL30388 | rna-NM_001179289.1_MUCL30388 | cds-NP_012028.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005286.1:400144-403638:- | gene-YHR158C_MUCL39482 | rna-NM_001179289.1_MUCL39482 | cds-NP_012028.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005430.1:406753-410247:- | gene-YHR158C_MUCL42920 | rna-NM_001179289.1_MUCL42920 | cds-NP_012028.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:413567-417061:- | gene-YHR158C_NCIM3186 | rna-NM_001179289.1_NCIM3186 | cds-NP_012028.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005270.1:402602-406096:- | gene-YHR158C_NCYC1407 | rna-NM_001179289.1_NCYC1407 | cds-NP_012028.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994147.1:401755-405249:- | gene-YHR158C_PE2H3 | rna-NM_001179289.1_PE2H3 | cds-NP_012028.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999879.1:409182-412676:- | gene-YHR158C_PE2H4 | rna-NM_001179289.1_PE2H4 | cds-NP_012028.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:413685-417179:- | gene-YHR158C_S288C | rna-NM_001179289.1_S288C | cds-NP_012028.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000070.1:34622-38116:+ | gene-YHR158C_SA1 | rna-NM_001179289.1_SA1 | cds-NP_012028.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005494.1:402853-406347:- | gene-YHR158C_ThermosaccDry | rna-NM_001179289.1_ThermosaccDry | cds-NP_012028.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005462.1:410677-414171:- | gene-YHR158C_VR1 | rna-NM_001179289.1_VR1 | cds-NP_012028.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000017.1:393093-396587:- | gene-YHR158C_ZTW1 | rna-NM_001179289.1_ZTW1 | cds-NP_012028.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047494.1:399235-402717:- | gene-YHR158C_Sparadoxus | rna-NM_001179289.1_Sparadoxus | cds-NP_012028.1_Sparadoxus | 88.0 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |