KDX1 (YKL161C)


Gene profile

Gene name: KDX1
Reference locus (S288C): YKL161C
Gene biotype: protein_coding

Description: Serine/threonine-protein kinase KDX1; Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication

Top 10 interactors (score): RLM1 (0.995); MKK2 (0.983); MKK1 (0.977); SKO1 (0.93); MSG5 (0.92); SDP1 (0.918); SWI4 (0.915); STE7 (0.907); SWI6 (0.904); RHO1 (0.9); BCK1 (0.821); PBS2 (0.815); PAF1 (0.8); PTC1 (0.781); SSN8 (0.772); SSN2 (0.761); ASK10 (0.748); STE4 (0.739); CRG1 (0.736); PRM5 (0.733)

Homologues (species, bitscore): MAPK7 (Homo sapiens, 278.1); Mapk7 (Mus musculus, 278.1); mapk7 (Danio rerio, 293.1); mapk7 (Xenopus tropicalis, 281.2); p38a (Drosophila melanogaster, 266.2); pmk-1 (Caenorhabditis elegans, 262.3); MPK6 (Arabidopsis thaliana, 308.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:136280-137581:- gene-YKL161C_AKU4011 rna-NM_001179727.1_AKU4011 cds-NP_012761.1_AKU4011 99.5 100.0 Verified 1 1 0 False False False True False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000030.1:112851-114152:- gene-YKL161C_BG1 rna-NM_001179727.1_BG1 cds-NP_012761.1_BG1 99.6 100.0 Verified 1 1 0 False False False True False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:153935-155236:- gene-YKL161C_Bruggeman rna-NM_001179727.1_Bruggeman cds-NP_012761.1_Bruggeman 99.6 100.0 Verified 1 1 0 False False False True False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:148752-150053:- gene-YKL161C_CAT1 rna-NM_001179727.1_CAT1 cds-NP_012761.1_CAT1 99.5 100.0 Verified 1 1 0 False False False True False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:148503-149804:- gene-YKL161C_CBS1585 rna-NM_001179727.1_CBS1585 cds-NP_012761.1_CBS1585 99.5 100.0 Verified 1 1 0 False False False True False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:147094-148395:- gene-YKL161C_CBS436 rna-NM_001179727.1_CBS436 cds-NP_012761.1_CBS436 99.5 100.0 Mismatch 1 1 0 False False False True False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:133528-134829:- gene-YKL161C_CBS6412 rna-NM_001179727.1_CBS6412 cds-NP_012761.1_CBS6412 99.4 100.0 Mismatch 1 1 0 False False False True False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:148974-150275:- gene-YKL161C_CBS6413 rna-NM_001179727.1_CBS6413 cds-NP_012761.1_CBS6413 99.5 100.0 Verified 1 1 0 False False False True False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:149033-150334:- gene-YKL161C_CENPK1137D rna-NM_001179727.1_CENPK1137D cds-NP_012761.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:147025-148326:- gene-YKL161C_EthanolRed rna-NM_001179727.1_EthanolRed cds-NP_012761.1_EthanolRed 99.9 100.0 Verified 1 1 0 False False False True False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:147837-149138:- gene-YKL161C_FaliES1 rna-NM_001179727.1_FaliES1 cds-NP_012761.1_FaliES1 99.9 100.0 Verified 1 1 0 False False False True False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000239.2:6802-8103:- gene-YKL161C_JAY291 rna-NM_001179727.1_JAY291 cds-NP_012761.1_JAY291 99.5 100.0 Verified 1 1 0 False False False True False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:156033-157334:- gene-YKL161C_MUCL30387 rna-NM_001179727.1_MUCL30387 cds-NP_012761.1_MUCL30387 99.4 100.0 Verified 1 1 0 False False False True False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:150387-151688:- gene-YKL161C_MUCL30388 rna-NM_001179727.1_MUCL30388 cds-NP_012761.1_MUCL30388 99.4 100.0 Verified 1 1 0 False False False True False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:148313-149614:- gene-YKL161C_MUCL39482 rna-NM_001179727.1_MUCL39482 cds-NP_012761.1_MUCL39482 99.5 100.0 Verified 1 1 0 False False False True False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:152718-154019:- gene-YKL161C_MUCL42920 rna-NM_001179727.1_MUCL42920 cds-NP_012761.1_MUCL42920 99.6 100.0 Verified 1 1 0 False False False True False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:149375-150676:- gene-YKL161C_NCIM3186 rna-NM_001179727.1_NCIM3186 cds-NP_012761.1_NCIM3186 99.2 100.0 Verified 1 1 0 False False True False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:148505-149806:- gene-YKL161C_NCYC1407 rna-NM_001179727.1_NCYC1407 cds-NP_012761.1_NCYC1407 99.4 100.0 Verified 1 1 0 False False False True False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:155579-156880:- gene-YKL161C_PE2H3 rna-NM_001179727.1_PE2H3 cds-NP_012761.1_PE2H3 99.6 100.0 Verified 1 1 0 False False False True False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:151873-153174:- gene-YKL161C_PE2H4 rna-NM_001179727.1_PE2H4 cds-NP_012761.1_PE2H4 99.6 100.0 Verified 1 1 0 False False False True False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:149386-150687:- gene-YKL161C_S288C rna-NM_001179727.1_S288C cds-NP_012761.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000008.1:65803-67104:- gene-YKL161C_SA1 rna-NM_001179727.1_SA1 cds-NP_012761.1_SA1 99.6 100.0 Verified 1 1 0 False False False True False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:148537-149838:- gene-YKL161C_ThermosaccDry rna-NM_001179727.1_ThermosaccDry cds-NP_012761.1_ThermosaccDry 99.9 100.0 Verified 1 1 0 False False False True False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:147372-148673:- gene-YKL161C_VR1 rna-NM_001179727.1_VR1 cds-NP_012761.1_VR1 99.5 100.0 Verified 1 1 0 False False False True False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:147155-148456:- gene-YKL161C_ZTW1 rna-NM_001179727.1_ZTW1 cds-NP_012761.1_ZTW1 99.4 100.0 Verified 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:163103-164404:- gene-YKL161C_Sparadoxus rna-NM_001179727.1_Sparadoxus cds-NP_012761.1_Sparadoxus 86.2 100.0 Verified 1 1 0 False False False True False

Additional files