Gene name: KCS1
Reference locus (S288C): YDR017C
Gene biotype: protein_coding
Description: Inositol-hexakisphosphate 5-kinase; Inositol hexakisphosphate and inositol heptakisphosphate kinase; generation of high energy inositol pyrophosphates by Kcs1p is required for many processes such as vacuolar biogenesis, stress response, RNA polymerase I-mediated rRNA transcription and telomere maintenance; inositol hexakisphosphate is also known as IP6; inositol heptakisphosphate is also known as IP7; Belongs to the inositol phosphokinase (IPK) family
Top 10 interactors (score): VIP1 (0.999); ARG82 (0.997); IPK1 (0.992); DDP1 (0.905); GLE1 (0.844); PLC1 (0.826); PHO81 (0.825); CMD1 (0.806); PHO85 (0.768); ADK1 (0.765); PHO84 (0.764); PHO80 (0.759); INO1 (0.752); TTI1 (0.724); PIS1 (0.704); IME4 (0.697); PHO3 (0.684); PHO4 (0.675); GCR1 (0.644); TUS1 (0.639)
Homologues (species, bitscore): IP6K3 (Homo sapiens, 115.5); Ip6k3 (Mus musculus, 119.4); ip6k1 (Danio rerio, 115.5); ip6k1 (Xenopus tropicalis, 115.2); CG10082 (Drosophila melanogaster, 112.1); F30A10.3 (Caenorhabditis elegans, 96.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:465046-468198:- | gene-YDR017C_AKU4011 | rna-NM_001180325.3_AKU4011 | cds-NP_010300.3_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:81599-84751:+ | gene-YDR017C_BG1 | rna-NM_001180325.3_BG1 | cds-NP_010300.3_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:493287-496439:- | gene-YDR017C_Bruggeman | rna-NM_001180325.3_Bruggeman | cds-NP_010300.3_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:478357-481509:- | gene-YDR017C_CAT1 | rna-NM_001180325.3_CAT1 | cds-NP_010300.3_CAT1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:461637-464789:- | gene-YDR017C_CBS1585 | rna-NM_001180325.3_CBS1585 | cds-NP_010300.3_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:478618-481770:- | gene-YDR017C_CBS436 | rna-NM_001180325.3_CBS436 | cds-NP_010300.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:458547-461699:- | gene-YDR017C_CBS6412 | rna-NM_001180325.3_CBS6412 | cds-NP_010300.3_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:480826-483978:- | gene-YDR017C_CBS6413 | rna-NM_001180325.3_CBS6413 | cds-NP_010300.3_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:478081-481233:- | gene-YDR017C_CENPK1137D | rna-NM_001180325.3_CENPK1137D | cds-NP_010300.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:473068-476220:- | gene-YDR017C_EthanolRed | rna-NM_001180325.3_EthanolRed | cds-NP_010300.3_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:479427-482579:- | gene-YDR017C_FaliES1 | rna-NM_001180325.3_FaliES1 | cds-NP_010300.3_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000042.1:31013-34165:+ | gene-YDR017C_JAY291 | rna-NM_001180325.3_JAY291 | cds-NP_010300.3_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:478867-482019:- | gene-YDR017C_MUCL30387 | rna-NM_001180325.3_MUCL30387 | cds-NP_010300.3_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:469329-472481:- | gene-YDR017C_MUCL30388 | rna-NM_001180325.3_MUCL30388 | cds-NP_010300.3_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:463006-466158:- | gene-YDR017C_MUCL39482 | rna-NM_001180325.3_MUCL39482 | cds-NP_010300.3_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:384653-387808:- | gene-YDR017C_MUCL42920 | rna-NM_001180325.3_MUCL42920 | cds-NP_010300.3_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:479038-482190:- | gene-YDR017C_NCIM3186 | rna-NM_001180325.3_NCIM3186 | cds-NP_010300.3_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:462438-465590:- | gene-YDR017C_NCYC1407 | rna-NM_001180325.3_NCYC1407 | cds-NP_010300.3_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:477526-480678:- | gene-YDR017C_PE2H3 | rna-NM_001180325.3_PE2H3 | cds-NP_010300.3_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:476831-479983:- | gene-YDR017C_PE2H4 | rna-NM_001180325.3_PE2H4 | cds-NP_010300.3_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:479115-482267:- | gene-YDR017C_S288C | rna-NM_001180325.3_S288C | cds-NP_010300.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000065.1:6289-9441:- | gene-YDR017C_SA1 | rna-NM_001180325.3_SA1 | cds-NP_010300.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:478906-482058:- | gene-YDR017C_ThermosaccDry | rna-NM_001180325.3_ThermosaccDry | cds-NP_010300.3_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:483477-486629:- | gene-YDR017C_VR1 | rna-NM_001180325.3_VR1 | cds-NP_010300.3_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:476801-479953:- | gene-YDR017C_ZTW1 | rna-NM_001180325.3_ZTW1 | cds-NP_010300.3_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:480581-483715:- | gene-YDR017C_Sparadoxus | rna-NM_001180325.3_Sparadoxus | cds-NP_010300.3_Sparadoxus | 89.7 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |