KAR4 (YCL055W)


Gene profile

Gene name: KAR4
Reference locus (S288C): YCL055W
Gene biotype: protein_coding

Description: Mrna m6a methyltransferase non-catalytic subunit; Karyogamy protein KAR4; Transcription factor required for response to pheromones; also required during meiosis; exists in two forms, a slower-migrating form more abundant during vegetative growth and a faster-migrating form induced by pheromone

Top 10 interactors (score): IME4 (0.999); FUS1 (0.946); STE12 (0.898); AGA1 (0.875); KAR3 (0.841); KSS1 (0.792); CIK1 (0.772); STE2 (0.768); PRM2 (0.754); FIG1 (0.75); KAR5 (0.74); FUS2 (0.714); THO2 (0.706); PRM3 (0.7); MTQ2 (0.695); SEC66 (0.694); PHO92 (0.683); JEM1 (0.682); SPB1 (0.67); SST2 (0.668)

Homologues (species, bitscore): METTL14 (Homo sapiens, 115.9); Mettl14 (Mus musculus, 116.3); mettl14 (Danio rerio, 117.1); mettl14 (Xenopus tropicalis, 115.5); CG7818 (Drosophila melanogaster, 115.9); EMB1691 (Arabidopsis thaliana, 125.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005297.1:29221-30228:+ gene-YCL055W_AKU4011 rna-NM_001178699.1_AKU4011 cds-NP_009876.1_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000086.1:15598-16605:- gene-YCL055W_BG1 rna-NM_001178699.1_BG1 cds-NP_009876.1_BG1 99.3 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005505.1:16632-17639:+ gene-YCL055W_Bruggeman rna-NM_001178699.1_Bruggeman cds-NP_009876.1_Bruggeman 99.3 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005521.1:29102-30109:+ gene-YCL055W_CAT1 rna-NM_001178699.1_CAT1 cds-NP_009876.1_CAT1 99.3 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005361.1:29904-30911:+ gene-YCL055W_CBS1585 rna-NM_001178699.1_CBS1585 cds-NP_009876.1_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005345.1:28453-29460:+ gene-YCL055W_CBS436 rna-NM_001178699.1_CBS436 cds-NP_009876.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005329.1:17660-18667:+ gene-YCL055W_CBS6412 rna-NM_001178699.1_CBS6412 cds-NP_009876.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005313.1:28678-29685:+ gene-YCL055W_CBS6413 rna-NM_001178699.1_CBS6413 cds-NP_009876.1_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001524.1:27515-28522:+ gene-YCL055W_CENPK1137D rna-NM_001178699.1_CENPK1137D cds-NP_009876.1_CENPK1137D 99.3 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005473.1:27454-28461:+ gene-YCL055W_EthanolRed rna-NM_001178699.1_EthanolRed cds-NP_009876.1_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005537.1:28217-29224:+ gene-YCL055W_FaliES1 rna-NM_001178699.1_FaliES1 cds-NP_009876.1_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000225.1:55114-56121:- gene-YCL055W_JAY291 rna-NM_001178699.1_JAY291 cds-NP_009876.1_JAY291 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005409.1:15637-16644:+ gene-YCL055W_MUCL30387 rna-NM_001178699.1_MUCL30387 cds-NP_009876.1_MUCL30387 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005441.1:15929-16936:+ gene-YCL055W_MUCL30388 rna-NM_001178699.1_MUCL30388 cds-NP_009876.1_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005281.1:30291-31298:+ gene-YCL055W_MUCL39482 rna-NM_001178699.1_MUCL39482 cds-NP_009876.1_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005425.1:16212-17219:+ gene-YCL055W_MUCL42920 rna-NM_001178699.1_MUCL42920 cds-NP_009876.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011812.1:27561-28568:+ gene-YCL055W_NCIM3186 rna-NM_001178699.1_NCIM3186 cds-NP_009876.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005265.1:30613-31620:+ gene-YCL055W_NCYC1407 rna-NM_001178699.1_NCYC1407 cds-NP_009876.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994142.1:28386-29393:+ gene-YCL055W_PE2H3 rna-NM_001178699.1_PE2H3 cds-NP_009876.1_PE2H3 99.3 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999874.1:28343-29350:+ gene-YCL055W_PE2H4 rna-NM_001178699.1_PE2H4 cds-NP_009876.1_PE2H4 99.3 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001135.5:27929-28936:+ gene-YCL055W_S288C rna-NM_001178699.1_S288C cds-NP_009876.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000061.1:15077-16084:+ gene-YCL055W_SA1 rna-NM_001178699.1_SA1 cds-NP_009876.1_SA1 99.3 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005489.1:28535-29542:+ gene-YCL055W_ThermosaccDry rna-NM_001178699.1_ThermosaccDry cds-NP_009876.1_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005457.1:33819-34826:+ gene-YCL055W_VR1 rna-NM_001178699.1_VR1 cds-NP_009876.1_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000004.1:28760-29767:+ gene-YCL055W_ZTW1 rna-NM_001178699.1_ZTW1 cds-NP_009876.1_ZTW1 99.4 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047489.1:58441-59445:+ gene-YCL055W_Sparadoxus rna-NM_001178699.1_Sparadoxus cds-NP_009876.1_Sparadoxus 91.1 99.7 Verified 1 1 1 False True False False False

Additional files