Gene name: KAR2
Reference locus (S288C): YJL034W
Gene biotype: protein_coding
Description: 78 kDa glucose-regulated protein homolog; ATPase involved in protein import into the ER; also acts as a chaperone to mediate protein folding in the ER and may play a role in ER export of soluble proteins; regulates the unfolded protein response via interaction with Ire1p
Top 10 interactors (score): SIL1 (0.999); HRD3 (0.999); IRE1 (0.999); YOS9 (0.999); PDI1 (0.999); SEC63 (0.999); LHS1 (0.999); CNE1 (0.999); EUG1 (0.999); SEC61 (0.999); SCJ1 (0.998); HSP60 (0.996); SEC62 (0.994); HSC82 (0.993); ERO1 (0.99); ERD2 (0.99); ERV29 (0.988); HSP82 (0.988); ERJ5 (0.987); YDJ1 (0.987)
Homologues (species, bitscore): HSPA5 (Homo sapiens, 860.1); Hspa5 (Mus musculus, 861.3); hspa5 (Danio rerio, 860.9); hspa5 (Xenopus tropicalis, 860.1); Hsc70-3 (Drosophila melanogaster, 840.9); hsp-3 (Caenorhabditis elegans, 844.7); BIP1 (Arabidopsis thaliana, 838.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:364284-366332:+ | gene-YJL034W_AKU4011 | rna-NM_001181468.3_AKU4011 | cds-NP_012500.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:247750-249798:- | gene-YJL034W_BG1 | rna-NM_001181468.3_BG1 | cds-NP_012500.3_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:378475-380523:+ | gene-YJL034W_Bruggeman | rna-NM_001181468.3_Bruggeman | cds-NP_012500.3_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:382434-384482:+ | gene-YJL034W_CAT1 | rna-NM_001181468.3_CAT1 | cds-NP_012500.3_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:375948-377996:+ | gene-YJL034W_CBS1585 | rna-NM_001181468.3_CBS1585 | cds-NP_012500.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:394305-396353:+ | gene-YJL034W_CBS436 | rna-NM_001181468.3_CBS436 | cds-NP_012500.3_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:364546-366594:+ | gene-YJL034W_CBS6412 | rna-NM_001181468.3_CBS6412 | cds-NP_012500.3_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:366426-368474:+ | gene-YJL034W_CBS6413 | rna-NM_001181468.3_CBS6413 | cds-NP_012500.3_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:363753-365801:+ | gene-YJL034W_CENPK1137D | rna-NM_001181468.3_CENPK1137D | cds-NP_012500.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:367500-369548:+ | gene-YJL034W_EthanolRed | rna-NM_001181468.3_EthanolRed | cds-NP_012500.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:379948-381996:+ | gene-YJL034W_FaliES1 | rna-NM_001181468.3_FaliES1 | cds-NP_012500.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000200.1:33432-35480:- | gene-YJL034W_JAY291 | rna-NM_001181468.3_JAY291 | cds-NP_012500.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:378716-380764:+ | gene-YJL034W_MUCL30387 | rna-NM_001181468.3_MUCL30387 | cds-NP_012500.3_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:374864-376912:+ | gene-YJL034W_MUCL30388 | rna-NM_001181468.3_MUCL30388 | cds-NP_012500.3_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:369272-371320:+ | gene-YJL034W_MUCL39482 | rna-NM_001181468.3_MUCL39482 | cds-NP_012500.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:374607-376655:+ | gene-YJL034W_MUCL42920 | rna-NM_001181468.3_MUCL42920 | cds-NP_012500.3_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:381306-383354:+ | gene-YJL034W_NCIM3186 | rna-NM_001181468.3_NCIM3186 | cds-NP_012500.3_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:367221-369269:+ | gene-YJL034W_NCYC1407 | rna-NM_001181468.3_NCYC1407 | cds-NP_012500.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:379298-381346:+ | gene-YJL034W_PE2H3 | rna-NM_001181468.3_PE2H3 | cds-NP_012500.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:378942-380990:+ | gene-YJL034W_PE2H4 | rna-NM_001181468.3_PE2H4 | cds-NP_012500.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:381327-383375:+ | gene-YJL034W_S288C | rna-NM_001181468.3_S288C | cds-NP_012500.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000003.1:176828-178876:+ | gene-YJL034W_SA1 | rna-NM_001181468.3_SA1 | cds-NP_012500.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:373609-375657:+ | gene-YJL034W_ThermosaccDry | rna-NM_001181468.3_ThermosaccDry | cds-NP_012500.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:375454-377502:+ | gene-YJL034W_VR1 | rna-NM_001181468.3_VR1 | cds-NP_012500.3_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:354273-356321:+ | gene-YJL034W_ZTW1 | rna-NM_001181468.3_ZTW1 | cds-NP_012500.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:379540-381588:+ | gene-YJL034W_Sparadoxus | rna-NM_001181468.3_Sparadoxus | cds-NP_012500.3_Sparadoxus | 93.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |