KAP123 (YER110C)


Gene profile

Gene name: KAP123
Reference locus (S288C): YER110C
Gene biotype: protein_coding

Description: Importin subunit beta-4; Karyopherin beta; mediates nuclear import of ribosomal proteins prior to assembly into ribosomes and import of histones H3 and H4; localizes to the nuclear pore, nucleus, and cytoplasm; exhibits genetic interactions with RAI1

Top 10 interactors (score): GSP1 (0.999); KAP95 (0.999); CRM1 (0.997); CSE1 (0.997); KAP104 (0.995); KAP114 (0.99); SRP1 (0.988); RPA135 (0.984); KAP120 (0.982); SXM1 (0.982); NUG1 (0.981); NMD5 (0.981); KRE33 (0.979); GSP2 (0.975); NUP116 (0.967); NOP1 (0.967); ERB1 (0.964); RPA190 (0.962); NUP100 (0.962); PWP2 (0.957)

Homologues (species, bitscore): IPO4 (Homo sapiens, 245.4); Ipo4 (Mus musculus, 232.6); ipo4 (Danio rerio, 246.5); ipo4 (Xenopus tropicalis, 245.7); Karybeta3 (Drosophila melanogaster, 165.6); imb-3 (Caenorhabditis elegans, 101.3); AT4G27640 (Arabidopsis thaliana, 285.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:372648-375989:- gene-YER110C_AKU4011 rna-NM_001179000.1_AKU4011 cds-NP_011035.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000011.1:49618-52959:+ gene-YER110C_BG1 rna-NM_001179000.1_BG1 cds-NP_011035.1_BG1 99.5 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:383123-386464:- gene-YER110C_Bruggeman rna-NM_001179000.1_Bruggeman cds-NP_011035.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:377659-381000:- gene-YER110C_CAT1 rna-NM_001179000.1_CAT1 cds-NP_011035.1_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:372043-375384:- gene-YER110C_CBS1585 rna-NM_001179000.1_CBS1585 cds-NP_011035.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:374747-378088:- gene-YER110C_CBS436 rna-NM_001179000.1_CBS436 cds-NP_011035.1_CBS436 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:371117-374458:- gene-YER110C_CBS6412 rna-NM_001179000.1_CBS6412 cds-NP_011035.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:377962-381303:- gene-YER110C_CBS6413 rna-NM_001179000.1_CBS6413 cds-NP_011035.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:376512-379853:- gene-YER110C_CENPK1137D rna-NM_001179000.1_CENPK1137D cds-NP_011035.1_CENPK1137D 99.6 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:372494-375835:- gene-YER110C_EthanolRed rna-NM_001179000.1_EthanolRed cds-NP_011035.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:372975-376316:- gene-YER110C_FaliES1 rna-NM_001179000.1_FaliES1 cds-NP_011035.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000174.1:15221-18562:+ gene-YER110C_JAY291 rna-NM_001179000.1_JAY291 cds-NP_011035.1_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:380070-383411:- gene-YER110C_MUCL30387 rna-NM_001179000.1_MUCL30387 cds-NP_011035.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:375015-378356:- gene-YER110C_MUCL30388 rna-NM_001179000.1_MUCL30388 cds-NP_011035.1_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:371067-374408:- gene-YER110C_MUCL39482 rna-NM_001179000.1_MUCL39482 cds-NP_011035.1_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:379559-382900:- gene-YER110C_MUCL42920 rna-NM_001179000.1_MUCL42920 cds-NP_011035.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:378761-382102:- gene-YER110C_NCIM3186 rna-NM_001179000.1_NCIM3186 cds-NP_011035.1_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:376600-379941:- gene-YER110C_NCYC1407 rna-NM_001179000.1_NCYC1407 cds-NP_011035.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:387149-390490:- gene-YER110C_PE2H3 rna-NM_001179000.1_PE2H3 cds-NP_011035.1_PE2H3 99.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:377090-380431:- gene-YER110C_PE2H4 rna-NM_001179000.1_PE2H4 cds-NP_011035.1_PE2H4 99.5 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:378762-382103:- gene-YER110C_S288C rna-NM_001179000.1_S288C cds-NP_011035.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000023.1:88381-91722:- gene-YER110C_SA1 rna-NM_001179000.1_SA1 cds-NP_011035.1_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:373772-377113:- gene-YER110C_ThermosaccDry rna-NM_001179000.1_ThermosaccDry cds-NP_011035.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:374837-378178:- gene-YER110C_VR1 rna-NM_001179000.1_VR1 cds-NP_011035.1_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000009.1:370891-374232:- gene-YER110C_ZTW1 rna-NM_001179000.1_ZTW1 cds-NP_011035.1_ZTW1 99.9 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:374875-378216:- gene-YER110C_Sparadoxus rna-NM_001179000.1_Sparadoxus cds-NP_011035.1_Sparadoxus 92.2 100.0 Verified 1 1 1 False True False False False

Additional files