Gene name: KAP114
Reference locus (S288C): YGL241W
Gene biotype: protein_coding
Description: Importin subunit beta-5; Karyopherin, responsible for nuclear import of specific proteins; cargoes include Spt15p, Sua7p, histones H2A and H2B, and Nap1p; amino terminus shows similarity to those of other importins, particularly Cse1p; localization is primarily nuclear; function is regulated by sumoylation; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): NAP1 (0.995); KAP123 (0.99); PSE1 (0.985); KAP104 (0.98); KAP95 (0.98); NMD5 (0.978); KAP122 (0.976); KAP120 (0.975); HTA1 (0.949); HTB1 (0.941); GSP1 (0.926); SXM1 (0.926); HTA2 (0.924); MSN5 (0.917); SPT15 (0.916); HTZ1 (0.914); SRP1 (0.906); MTR10 (0.894); CRM1 (0.857); CSE1 (0.843)
Homologues (species, bitscore): IPO9 (Homo sapiens, 129.0); Ipo9 (Mus musculus, 125.9); ipo9 (Danio rerio, 119.8); ipo9 (Xenopus tropicalis, 115.9); Ranbp9 (Drosophila melanogaster, 81.3); AT1G26170 (Arabidopsis thaliana, 96.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:46978-49992:+ | gene-YGL241W_AKU4011 | rna-NM_001181107.1_AKU4011 | cds-NP_011273.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000175.1:39010-42024:+ | gene-YGL241W_BG1 | rna-NM_001181107.1_BG1 | cds-NP_011273.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:47326-50340:+ | gene-YGL241W_Bruggeman | rna-NM_001181107.1_Bruggeman | cds-NP_011273.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:45397-48411:+ | gene-YGL241W_CAT1 | rna-NM_001181107.1_CAT1 | cds-NP_011273.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:51266-54280:+ | gene-YGL241W_CBS1585 | rna-NM_001181107.1_CBS1585 | cds-NP_011273.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:45987-49001:+ | gene-YGL241W_CBS436 | rna-NM_001181107.1_CBS436 | cds-NP_011273.1_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:38835-41849:+ | gene-YGL241W_CBS6412 | rna-NM_001181107.1_CBS6412 | cds-NP_011273.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:45122-48136:+ | gene-YGL241W_CBS6413 | rna-NM_001181107.1_CBS6413 | cds-NP_011273.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:45106-48120:+ | gene-YGL241W_CENPK1137D | rna-NM_001181107.1_CENPK1137D | cds-NP_011273.1_CENPK1137D | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:38066-41080:+ | gene-YGL241W_EthanolRed | rna-NM_001181107.1_EthanolRed | cds-NP_011273.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:38651-41665:+ | gene-YGL241W_FaliES1 | rna-NM_001181107.1_FaliES1 | cds-NP_011273.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000079.1:25458-28472:- | gene-YGL241W_JAY291 | rna-NM_001181107.1_JAY291 | cds-NP_011273.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:47264-50278:+ | gene-YGL241W_MUCL30387 | rna-NM_001181107.1_MUCL30387 | cds-NP_011273.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:49416-52430:+ | gene-YGL241W_MUCL30388 | rna-NM_001181107.1_MUCL30388 | cds-NP_011273.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:47863-50877:+ | gene-YGL241W_MUCL39482 | rna-NM_001181107.1_MUCL39482 | cds-NP_011273.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:50749-53763:+ | gene-YGL241W_MUCL42920 | rna-NM_001181107.1_MUCL42920 | cds-NP_011273.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:45445-48459:+ | gene-YGL241W_NCIM3186 | rna-NM_001181107.1_NCIM3186 | cds-NP_011273.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:39623-42637:+ | gene-YGL241W_NCYC1407 | rna-NM_001181107.1_NCYC1407 | cds-NP_011273.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:41476-44490:+ | gene-YGL241W_PE2H3 | rna-NM_001181107.1_PE2H3 | cds-NP_011273.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:41024-44038:+ | gene-YGL241W_PE2H4 | rna-NM_001181107.1_PE2H4 | cds-NP_011273.1_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:45445-48459:+ | gene-YGL241W_S288C | rna-NM_001181107.1_S288C | cds-NP_011273.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:326874-329888:- | gene-YGL241W_SA1 | rna-NM_001181107.1_SA1 | cds-NP_011273.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:38957-41971:+ | gene-YGL241W_ThermosaccDry | rna-NM_001181107.1_ThermosaccDry | cds-NP_011273.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:45912-48926:+ | gene-YGL241W_VR1 | rna-NM_001181107.1_VR1 | cds-NP_011273.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:38002-41016:+ | gene-YGL241W_ZTW1 | rna-NM_001181107.1_ZTW1 | cds-NP_011273.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:46695-49709:+ | gene-YGL241W_Sparadoxus | rna-NM_001181107.1_Sparadoxus | cds-NP_011273.1_Sparadoxus | 86.5 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |