Gene name: KAE1
Reference locus (S288C): YKR038C
Gene biotype: protein_coding
Description: tRNA N6-adenosine threonylcarbamoyltransferase; Highly conserved ATPase of HSP70/DnaK family; essential functional component of the EKC/KEOPS complex, with Bud32p, Cgi121p, Pcc1p, and Gon7p; EKC/KEOPS complex is required for t6A tRNA modification and telomeric TG1-3 recombination; may have role in transcription
Top 10 interactors (score): CGI121 (0.999); BUD32 (0.999); GON7 (0.999); PCC1 (0.995); SUA5 (0.982); QRI7 (0.826); GUS1 (0.808); GRX4 (0.743); SRP54 (0.738); HOM2 (0.727); RAD2 (0.724); PIB2 (0.709); SLM3 (0.699); TRM1 (0.676); MRPL51 (0.653); THR1 (0.651); NIP7 (0.648); IKI3 (0.643); HAM1 (0.642); GCN2 (0.642)
Homologues (species, bitscore): OSGEP (Homo sapiens, 434.1); Osgep (Mus musculus, 427.9); osgep (Danio rerio, 433.7); osgep (Xenopus tropicalis, 434.9); CG4933 (Drosophila melanogaster, 443.4); Y71H2AM.1 (Caenorhabditis elegans, 417.9); AT4G22720 (Arabidopsis thaliana, 420.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:497674-498834:- | gene-YKR038C_AKU4011 | rna-NM_001179828.1_AKU4011 | cds-NP_012964.2_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000113.1:144642-145802:+ | gene-YKR038C_BG1 | rna-NM_001179828.1_BG1 | cds-NP_012964.2_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:519853-521013:- | gene-YKR038C_Bruggeman | rna-NM_001179828.1_Bruggeman | cds-NP_012964.2_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:515102-516262:- | gene-YKR038C_CAT1 | rna-NM_001179828.1_CAT1 | cds-NP_012964.2_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:510414-511574:- | gene-YKR038C_CBS1585 | rna-NM_001179828.1_CBS1585 | cds-NP_012964.2_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:509256-510416:- | gene-YKR038C_CBS436 | rna-NM_001179828.1_CBS436 | cds-NP_012964.2_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:494575-495735:- | gene-YKR038C_CBS6412 | rna-NM_001179828.1_CBS6412 | cds-NP_012964.2_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:510243-511403:- | gene-YKR038C_CBS6413 | rna-NM_001179828.1_CBS6413 | cds-NP_012964.2_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:511811-512971:- | gene-YKR038C_CENPK1137D | rna-NM_001179828.1_CENPK1137D | cds-NP_012964.2_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:507940-509100:- | gene-YKR038C_EthanolRed | rna-NM_001179828.1_EthanolRed | cds-NP_012964.2_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:511073-512233:- | gene-YKR038C_FaliES1 | rna-NM_001179828.1_FaliES1 | cds-NP_012964.2_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000077.1:41512-42672:+ | gene-YKR038C_JAY291 | rna-NM_001179828.1_JAY291 | cds-NP_012964.2_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:520002-521162:- | gene-YKR038C_MUCL30387 | rna-NM_001179828.1_MUCL30387 | cds-NP_012964.2_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:514611-515771:- | gene-YKR038C_MUCL30388 | rna-NM_001179828.1_MUCL30388 | cds-NP_012964.2_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:509732-510892:- | gene-YKR038C_MUCL39482 | rna-NM_001179828.1_MUCL39482 | cds-NP_012964.2_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:515764-516924:- | gene-YKR038C_MUCL42920 | rna-NM_001179828.1_MUCL42920 | cds-NP_012964.2_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:511988-513148:- | gene-YKR038C_NCIM3186 | rna-NM_001179828.1_NCIM3186 | cds-NP_012964.2_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:509938-511098:- | gene-YKR038C_NCYC1407 | rna-NM_001179828.1_NCYC1407 | cds-NP_012964.2_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:534939-536099:- | gene-YKR038C_PE2H3 | rna-NM_001179828.1_PE2H3 | cds-NP_012964.2_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:519662-520822:- | gene-YKR038C_PE2H4 | rna-NM_001179828.1_PE2H4 | cds-NP_012964.2_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:511999-513159:- | gene-YKR038C_S288C | rna-NM_001179828.1_S288C | cds-NP_012964.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000078.1:575-1735:+ | gene-YKR038C_SA1 | rna-NM_001179828.1_SA1 | cds-NP_012964.2_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:510326-511486:- | gene-YKR038C_ThermosaccDry | rna-NM_001179828.1_ThermosaccDry | cds-NP_012964.2_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:509960-511120:- | gene-YKR038C_VR1 | rna-NM_001179828.1_VR1 | cds-NP_012964.2_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:508373-509533:- | gene-YKR038C_ZTW1 | rna-NM_001179828.1_ZTW1 | cds-NP_012964.2_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:533661-534821:- | gene-YKR038C_Sparadoxus | rna-NM_001179828.1_Sparadoxus | cds-NP_012964.2_Sparadoxus | 90.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |