JJJ1 (YNL227C)


Gene profile

Gene name: JJJ1
Reference locus (S288C): YNL227C
Gene biotype: protein_coding

Description: Dnaj homolog subfamily a member 5; J protein JJJ1; Co-chaperone that stimulates the ATPase activity of Ssa1p; required for a late step of ribosome biogenesis; associated with the cytosolic large ribosomal subunit; contains a J-domain; mutation causes defects in fluid-phase endocytosis

Top 10 interactors (score): REI1 (0.999); ARX1 (0.995); NMD3 (0.993); TIF6 (0.989); RLP24 (0.988); NOG2 (0.979); NUG1 (0.974); MAK21 (0.974); YVH1 (0.969); RPF2 (0.968); RPL3 (0.965); YTM1 (0.965); MRT4 (0.956); BUD20 (0.956); RPL25 (0.955); AFG2 (0.955); CIC1 (0.952); NOG1 (0.95); SSF1 (0.95); RRS1 (0.943)

Homologues (species, bitscore): DNAJC21 (Homo sapiens, 228.0); Dnajc21 (Mus musculus, 229.6); dnajc21 (Danio rerio, 219.9); dnajc21 (Xenopus tropicalis, 222.2); CG2790 (Drosophila melanogaster, 211.5); dnj-17 (Caenorhabditis elegans, 194.9); AT1G74250 (Arabidopsis thaliana, 193.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:214437-216209:- gene-YNL227C_AKU4011 rna-NM_001183065.1_AKU4011 cds-NP_014172.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:118382-120154:- gene-YNL227C_BG1 rna-NM_001183065.1_BG1 cds-NP_014172.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:224488-226260:- gene-YNL227C_Bruggeman rna-NM_001183065.1_Bruggeman cds-NP_014172.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:231644-233416:- gene-YNL227C_CAT1 rna-NM_001183065.1_CAT1 cds-NP_014172.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:214834-216606:- gene-YNL227C_CBS1585 rna-NM_001183065.1_CBS1585 cds-NP_014172.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:209920-211692:- gene-YNL227C_CBS436 rna-NM_001183065.1_CBS436 cds-NP_014172.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:210868-212640:- gene-YNL227C_CBS6412 rna-NM_001183065.1_CBS6412 cds-NP_014172.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:211516-213288:- gene-YNL227C_CBS6413 rna-NM_001183065.1_CBS6413 cds-NP_014172.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:214464-216235:- gene-YNL227C_CENPK1137D rna-NM_001183065.1_CENPK1137D cds-NP_014172.1_CENPK1137D 99.3 99.9 Unannotated 1 1 0 False False False True False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:212087-213859:- gene-YNL227C_EthanolRed rna-NM_001183065.1_EthanolRed cds-NP_014172.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:206829-208601:- gene-YNL227C_FaliES1 rna-NM_001183065.1_FaliES1 cds-NP_014172.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000082.1:117974-119746:- gene-YNL227C_JAY291 rna-NM_001183065.1_JAY291 cds-NP_014172.1_JAY291 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:220022-221794:- gene-YNL227C_MUCL30387 rna-NM_001183065.1_MUCL30387 cds-NP_014172.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:218607-220379:- gene-YNL227C_MUCL30388 rna-NM_001183065.1_MUCL30388 cds-NP_014172.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:212324-214096:- gene-YNL227C_MUCL39482 rna-NM_001183065.1_MUCL39482 cds-NP_014172.1_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:214579-216351:- gene-YNL227C_MUCL42920 rna-NM_001183065.1_MUCL42920 cds-NP_014172.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:220628-222400:- gene-YNL227C_NCIM3186 rna-NM_001183065.1_NCIM3186 cds-NP_014172.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:214417-216189:- gene-YNL227C_NCYC1407 rna-NM_001183065.1_NCYC1407 cds-NP_014172.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:211317-213089:- gene-YNL227C_PE2H3 rna-NM_001183065.1_PE2H3 cds-NP_014172.1_PE2H3 99.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:210705-212477:- gene-YNL227C_PE2H4 rna-NM_001183065.1_PE2H4 cds-NP_014172.1_PE2H4 99.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:220659-222431:- gene-YNL227C_S288C rna-NM_001183065.1_S288C cds-NP_014172.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000040.1:29873-31645:+ gene-YNL227C_SA1 rna-NM_001183065.1_SA1 cds-NP_014172.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:207685-209457:- gene-YNL227C_ThermosaccDry rna-NM_001183065.1_ThermosaccDry cds-NP_014172.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:226673-228445:- gene-YNL227C_VR1 rna-NM_001183065.1_VR1 cds-NP_014172.1_VR1 99.9 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:118003-119774:- gene-YNL227C_ZTW1 rna-NM_001183065.1_ZTW1 cds-NP_014172.1_ZTW1 99.4 99.9 Unannotated 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:218065-219837:- gene-YNL227C_Sparadoxus rna-NM_001183065.1_Sparadoxus cds-NP_014172.1_Sparadoxus 89.0 99.9 Verified 1 1 1 False True False False False

Additional files