JAC1 (YGL018C)


Gene profile

Gene name: JAC1
Reference locus (S288C): YGL018C
Gene biotype: protein_coding

Description: J-type co-chaperone JAC1, mitochondrial; Specialized J-protein that functions in Fe-S cluster biogenesis; functions with Hsp70 in Fe-S cluster biogenesis in mitochondria; involved in iron metabolism; contains a J domain typical to J-type chaperones; localizes to the mitochondrial matrix

Top 10 interactors (score): ISU1 (0.999); GRX5 (0.999); SSQ1 (0.999); ISU2 (0.999); YFH1 (0.998); ISA2 (0.998); NFS1 (0.997); ISA1 (0.996); MGE1 (0.994); ISD11 (0.992); YAH1 (0.986); IBA57 (0.982); PAM18 (0.977); SDH2 (0.962); NFU1 (0.959); MDJ1 (0.951); ECM10 (0.937); HSP60 (0.929); SSC1 (0.929); JEM1 (0.916)

Homologues (species, bitscore): HSCB (Homo sapiens, 65.9); Hscb (Mus musculus, 62.0); HSCB (Danio rerio, 79.0); hscb (Xenopus tropicalis, 60.5); Hsc20 (Drosophila melanogaster, 58.2); dnj-15 (Caenorhabditis elegans, 59.3); AT5G06410 (Arabidopsis thaliana, 58.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:461174-461728:- gene-YGL018C_AKU4011 rna-NM_001180883.1_AKU4011 cds-NP_011497.1_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000060.1:114411-114965:+ gene-YGL018C_BG1 rna-NM_001180883.1_BG1 cds-NP_011497.1_BG1 99.2 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:462127-462681:- gene-YGL018C_Bruggeman rna-NM_001180883.1_Bruggeman cds-NP_011497.1_Bruggeman 99.8 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:460423-460977:- gene-YGL018C_CAT1 rna-NM_001180883.1_CAT1 cds-NP_011497.1_CAT1 99.2 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:462645-463199:- gene-YGL018C_CBS1585 rna-NM_001180883.1_CBS1585 cds-NP_011497.1_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:456985-457539:- gene-YGL018C_CBS436 rna-NM_001180883.1_CBS436 cds-NP_011497.1_CBS436 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:455260-455814:- gene-YGL018C_CBS6412 rna-NM_001180883.1_CBS6412 cds-NP_011497.1_CBS6412 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:459317-459871:- gene-YGL018C_CBS6413 rna-NM_001180883.1_CBS6413 cds-NP_011497.1_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:458947-459501:- gene-YGL018C_CENPK1137D rna-NM_001180883.1_CENPK1137D cds-NP_011497.1_CENPK1137D 99.8 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:449541-450095:- gene-YGL018C_EthanolRed rna-NM_001180883.1_EthanolRed cds-NP_011497.1_EthanolRed 99.6 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:452779-453333:- gene-YGL018C_FaliES1 rna-NM_001180883.1_FaliES1 cds-NP_011497.1_FaliES1 99.6 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000177.1:21498-22052:- gene-YGL018C_JAY291 rna-NM_001180883.1_JAY291 cds-NP_011497.1_JAY291 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:459356-459910:- gene-YGL018C_MUCL30387 rna-NM_001180883.1_MUCL30387 cds-NP_011497.1_MUCL30387 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:461905-462459:- gene-YGL018C_MUCL30388 rna-NM_001180883.1_MUCL30388 cds-NP_011497.1_MUCL30388 99.8 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:458484-459038:- gene-YGL018C_MUCL39482 rna-NM_001180883.1_MUCL39482 cds-NP_011497.1_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:467909-468463:- gene-YGL018C_MUCL42920 rna-NM_001180883.1_MUCL42920 cds-NP_011497.1_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:459110-459664:- gene-YGL018C_NCIM3186 rna-NM_001180883.1_NCIM3186 cds-NP_011497.1_NCIM3186 99.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:452506-453060:- gene-YGL018C_NCYC1407 rna-NM_001180883.1_NCYC1407 cds-NP_011497.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:455163-455717:- gene-YGL018C_PE2H3 rna-NM_001180883.1_PE2H3 cds-NP_011497.1_PE2H3 99.2 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:460213-460767:- gene-YGL018C_PE2H4 rna-NM_001180883.1_PE2H4 cds-NP_011497.1_PE2H4 99.2 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:459110-459664:- gene-YGL018C_S288C rna-NM_001180883.1_S288C cds-NP_011497.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000021.1:95936-96490:+ gene-YGL018C_SA1 rna-NM_001180883.1_SA1 cds-NP_011497.1_SA1 99.2 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:472104-472658:- gene-YGL018C_ThermosaccDry rna-NM_001180883.1_ThermosaccDry cds-NP_011497.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:562179-562733:- gene-YGL018C_VR1 rna-NM_001180883.1_VR1 cds-NP_011497.1_VR1 99.2 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000014.1:450729-451283:- gene-YGL018C_ZTW1 rna-NM_001180883.1_ZTW1 cds-NP_011497.1_ZTW1 99.6 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:460330-460884:- gene-YGL018C_Sparadoxus rna-NM_001180883.1_Sparadoxus cds-NP_011497.1_Sparadoxus 89.5 100.0 Verified 1 1 1 False True False False False

Additional files