IZH3 (YLR023C)


Gene profile

Gene name: IZH3
Reference locus (S288C): YLR023C
Gene biotype: protein_coding

Description: ADIPOR-like receptor IZH3; Membrane protein involved in zinc ion homeostasis; member of the four-protein IZH family, expression induced by zinc deficiency; deletion reduces sensitivity to elevated zinc and shortens lag phase, overexpression reduces Zap1p activity

Top 10 interactors (score): IZH4 (0.977); ZAP1 (0.915); YOR012W (0.715); FET3 (0.702); MPD2 (0.697); INA1 (0.694); TGL3 (0.66); FMP30 (0.626); SCS7 (0.62); YEL034C-A (0.618); EMC6 (0.616); IRC11 (0.614); STE4 (0.59); PLB3 (0.573); EPS1 (0.571); GPA1 (0.536); PLB2 (0.526); GPA2 (0.517); ARB1 (0.504); EUG1 (0.492)

Homologues (species, bitscore): ADIPOR1 (Homo sapiens, 88.6); Adipor1 (Mus musculus, 89.4); adipor1b (Danio rerio, 85.9); adipor2 (Xenopus tropicalis, 87.0); AdipoR (Drosophila melanogaster, 89.4); paqr-1 (Caenorhabditis elegans, 88.2); HHP1 (Arabidopsis thaliana, 90.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:173438-175069:- gene-YLR023C_AKU4011 rna-NM_001181910.1_AKU4011 cds-NP_013123.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000212.1:136709-138340:- gene-YLR023C_BG1 rna-NM_001181910.1_BG1 cds-NP_013123.1_BG1 99.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:183832-185463:- gene-YLR023C_Bruggeman rna-NM_001181910.1_Bruggeman cds-NP_013123.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:184154-185785:- gene-YLR023C_CAT1 rna-NM_001181910.1_CAT1 cds-NP_013123.1_CAT1 99.9 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:181062-182693:- gene-YLR023C_CBS1585 rna-NM_001181910.1_CBS1585 cds-NP_013123.1_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:171695-173326:- gene-YLR023C_CBS436 rna-NM_001181910.1_CBS436 cds-NP_013123.1_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:179473-181104:- gene-YLR023C_CBS6412 rna-NM_001181910.1_CBS6412 cds-NP_013123.1_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:181325-182956:- gene-YLR023C_CBS6413 rna-NM_001181910.1_CBS6413 cds-NP_013123.1_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:170749-172380:- gene-YLR023C_CENPK1137D rna-NM_001181910.1_CENPK1137D cds-NP_013123.1_CENPK1137D 99.3 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:173449-175080:- gene-YLR023C_EthanolRed rna-NM_001181910.1_EthanolRed cds-NP_013123.1_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:173019-174650:- gene-YLR023C_FaliES1 rna-NM_001181910.1_FaliES1 cds-NP_013123.1_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000431.1:17213-18844:- gene-YLR023C_JAY291 rna-NM_001181910.1_JAY291 cds-NP_013123.1_JAY291 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:181180-182811:- gene-YLR023C_MUCL30387 rna-NM_001181910.1_MUCL30387 cds-NP_013123.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:187803-189434:- gene-YLR023C_MUCL30388 rna-NM_001181910.1_MUCL30388 cds-NP_013123.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:181557-183188:- gene-YLR023C_MUCL39482 rna-NM_001181910.1_MUCL39482 cds-NP_013123.1_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:181459-183090:- gene-YLR023C_MUCL42920 rna-NM_001181910.1_MUCL42920 cds-NP_013123.1_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:185472-187103:- gene-YLR023C_NCIM3186 rna-NM_001181910.1_NCIM3186 cds-NP_013123.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:173177-174808:- gene-YLR023C_NCYC1407 rna-NM_001181910.1_NCYC1407 cds-NP_013123.1_NCYC1407 99.2 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:179492-181123:- gene-YLR023C_PE2H3 rna-NM_001181910.1_PE2H3 cds-NP_013123.1_PE2H3 99.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:179233-180864:- gene-YLR023C_PE2H4 rna-NM_001181910.1_PE2H4 cds-NP_013123.1_PE2H4 99.5 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:185498-187129:- gene-YLR023C_S288C rna-NM_001181910.1_S288C cds-NP_013123.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000046.1:17348-18979:- gene-YLR023C_SA1 rna-NM_001181910.1_SA1 cds-NP_013123.1_SA1 99.9 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:173524-175155:- gene-YLR023C_ThermosaccDry rna-NM_001181910.1_ThermosaccDry cds-NP_013123.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:186941-188572:- gene-YLR023C_VR1 rna-NM_001181910.1_VR1 cds-NP_013123.1_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000023.1:172888-174519:- gene-YLR023C_ZTW1 rna-NM_001181910.1_ZTW1 cds-NP_013123.1_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:181677-183308:- gene-YLR023C_Sparadoxus rna-NM_001181910.1_Sparadoxus cds-NP_013123.1_Sparadoxus 89.7 99.6 Verified 1 1 1 False True False False False

Additional files