Gene name: IZH2
Reference locus (S288C): YOL002C
Gene biotype: protein_coding
Description: ADIPOR-like receptor IZH2; Plasma membrane receptor for plant antifungal osmotin; involved in zinc ion homeostasis, apoptosis; negatively regulates ZRT1 and other functionally divergent genes through CCCTC promoter motif (IzRE); modulates FET3 activity in iron-independent manner; affects gene expression by influencing balance of competition between Msn2p/Msn4p and Nrg1p/Nrg2p for binding to IzRE; transcription regulated by Zap1p, zinc, fatty acid levels; homolog of mammalian adiponectin receptor
Top 10 interactors (score): ZAP1 (0.92); OLE1 (0.809); FET3 (0.714); EOS1 (0.7); RAS2 (0.678); ZPS1 (0.674); YKL068W-A (0.656); NRG2 (0.637); YOR012W (0.616); YMR317W (0.614); INA1 (0.603); MPD2 (0.57); IZH4 (0.563); RSR1 (0.552); YPC1 (0.526); PLB2 (0.526); HNT1 (0.526); YOR387C (0.526); FAT3 (0.526); GPA1 (0.517)
Homologues (species, bitscore): ADIPOR1 (Homo sapiens, 181.8); Adipor2 (Mus musculus, 182.6); adipor2 (Danio rerio, 184.5); adipor2 (Xenopus tropicalis, 181.4); AdipoR (Drosophila melanogaster, 200.3); paqr-1 (Caenorhabditis elegans, 186.4); HHP3 (Arabidopsis thaliana, 132.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:307800-308753:- | gene-YOL002C_AKU4011 | rna-NM_001183256.1_AKU4011 | cds-NP_014641.2_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000152.1:123366-124319:- | gene-YOL002C_BG1 | rna-NM_001183256.1_BG1 | cds-NP_014641.2_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:310575-311528:- | gene-YOL002C_Bruggeman | rna-NM_001183256.1_Bruggeman | cds-NP_014641.2_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:308708-309661:- | gene-YOL002C_CAT1 | rna-NM_001183256.1_CAT1 | cds-NP_014641.2_CAT1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:302476-303429:- | gene-YOL002C_CBS1585 | rna-NM_001183256.1_CBS1585 | cds-NP_014641.2_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:306717-307670:- | gene-YOL002C_CBS436 | rna-NM_001183256.1_CBS436 | cds-NP_014641.2_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:301780-302733:- | gene-YOL002C_CBS6412 | rna-NM_001183256.1_CBS6412 | cds-NP_014641.2_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:309313-310266:- | gene-YOL002C_CBS6413 | rna-NM_001183256.1_CBS6413 | cds-NP_014641.2_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:323125-324078:- | gene-YOL002C_CENPK1137D | rna-NM_001183256.1_CENPK1137D | cds-NP_014641.2_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:304565-305518:- | gene-YOL002C_EthanolRed | rna-NM_001183256.1_EthanolRed | cds-NP_014641.2_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:307892-308845:- | gene-YOL002C_FaliES1 | rna-NM_001183256.1_FaliES1 | cds-NP_014641.2_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000015.1:20417-21370:+ | gene-YOL002C_JAY291 | rna-NM_001183256.1_JAY291 | cds-NP_014641.2_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:314790-315743:- | gene-YOL002C_MUCL30387 | rna-NM_001183256.1_MUCL30387 | cds-NP_014641.2_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:318226-319179:- | gene-YOL002C_MUCL30388 | rna-NM_001183256.1_MUCL30388 | cds-NP_014641.2_MUCL30388 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:309959-310912:- | gene-YOL002C_MUCL39482 | rna-NM_001183256.1_MUCL39482 | cds-NP_014641.2_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:324813-325766:- | gene-YOL002C_MUCL42920 | rna-NM_001183256.1_MUCL42920 | cds-NP_014641.2_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:323300-324253:- | gene-YOL002C_NCIM3186 | rna-NM_001183256.1_NCIM3186 | cds-NP_014641.2_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:316645-317598:- | gene-YOL002C_NCYC1407 | rna-NM_001183256.1_NCYC1407 | cds-NP_014641.2_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:311306-312259:- | gene-YOL002C_PE2H3 | rna-NM_001183256.1_PE2H3 | cds-NP_014641.2_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:321685-322638:- | gene-YOL002C_PE2H4 | rna-NM_001183256.1_PE2H4 | cds-NP_014641.2_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:323411-324364:- | gene-YOL002C_S288C | rna-NM_001183256.1_S288C | cds-NP_014641.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:291393-292346:- | gene-YOL002C_SA1 | rna-NM_001183256.1_SA1 | cds-NP_014641.2_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:306463-307416:- | gene-YOL002C_ThermosaccDry | rna-NM_001183256.1_ThermosaccDry | cds-NP_014641.2_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:307268-308221:- | gene-YOL002C_VR1 | rna-NM_001183256.1_VR1 | cds-NP_014641.2_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:41128-42081:- | gene-YOL002C_ZTW1 | rna-NM_001183256.1_ZTW1 | cds-NP_014641.2_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:314853-315806:- | gene-YOL002C_Sparadoxus | rna-NM_001183256.1_Sparadoxus | cds-NP_014641.2_Sparadoxus | 92.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |