IZH1 (YDR492W)


Gene profile

Gene name: IZH1
Reference locus (S288C): YDR492W
Gene biotype: protein_coding

Description: ADIPOR-like receptor IZH1; Membrane protein involved in zinc ion homeostasis; member of the four-protein IZH family; transcription is regulated directly by Zap1p, expression induced by zinc deficiency and fatty acids; deletion increases sensitivity to elevated zinc; IZH1 has a paralog, IZH4, that arose from the whole genome duplication

Top 10 interactors (score): ZAP1 (0.92); INA1 (0.77); FET3 (0.662); OLE1 (0.647); YOR012W (0.572); ZRT1 (0.571); MPD2 (0.526); COS111 (0.524); GPA1 (0.517); GPA2 (0.517); SCM4 (0.515); STE4 (0.51); STP3 (0.509); FAT3 (0.499); NRG2 (0.477); PLB2 (0.471); ZPS1 (0.453); MOH1 (0.451); IZH4 (0.42); IZH3 (0.41)

Homologues (species, bitscore): ADIPOR1 (Homo sapiens, 150.6); Adipor1 (Mus musculus, 150.6); adipor1a (Danio rerio, 146.7); adipor1 (Xenopus tropicalis, 149.8); AdipoR (Drosophila melanogaster, 161.8); paqr-2 (Caenorhabditis elegans, 155.6); HHP2 (Arabidopsis thaliana, 134.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:1374909-1375859:+ gene-YDR492W_AKU4011 rna-NM_001180800.1_AKU4011 cds-NP_010780.1_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000073.1:16463-17413:+ gene-YDR492W_BG1 rna-NM_001180800.1_BG1 cds-NP_010780.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:1406255-1407205:+ gene-YDR492W_Bruggeman rna-NM_001180800.1_Bruggeman cds-NP_010780.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:1383409-1384359:+ gene-YDR492W_CAT1 rna-NM_001180800.1_CAT1 cds-NP_010780.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:1369151-1370101:+ gene-YDR492W_CBS1585 rna-NM_001180800.1_CBS1585 cds-NP_010780.1_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:1388504-1389454:+ gene-YDR492W_CBS436 rna-NM_001180800.1_CBS436 cds-NP_010780.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:1364793-1365743:+ gene-YDR492W_CBS6412 rna-NM_001180800.1_CBS6412 cds-NP_010780.1_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:1387808-1388758:+ gene-YDR492W_CBS6413 rna-NM_001180800.1_CBS6413 cds-NP_010780.1_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:1433620-1434570:+ gene-YDR492W_CENPK1137D rna-NM_001180800.1_CENPK1137D cds-NP_010780.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:1378200-1379150:+ gene-YDR492W_EthanolRed rna-NM_001180800.1_EthanolRed cds-NP_010780.1_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:1381753-1382703:+ gene-YDR492W_FaliES1 rna-NM_001180800.1_FaliES1 cds-NP_010780.1_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000026.1:79998-80948:+ gene-YDR492W_JAY291 rna-NM_001180800.1_JAY291 cds-NP_010780.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:1388753-1389703:+ gene-YDR492W_MUCL30387 rna-NM_001180800.1_MUCL30387 cds-NP_010780.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:1370773-1371723:+ gene-YDR492W_MUCL30388 rna-NM_001180800.1_MUCL30388 cds-NP_010780.1_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:1360636-1361586:+ gene-YDR492W_MUCL39482 rna-NM_001180800.1_MUCL39482 cds-NP_010780.1_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:1303426-1304376:+ gene-YDR492W_MUCL42920 rna-NM_001180800.1_MUCL42920 cds-NP_010780.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:1434847-1435797:+ gene-YDR492W_NCIM3186 rna-NM_001180800.1_NCIM3186 cds-NP_010780.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:1374423-1375373:+ gene-YDR492W_NCYC1407 rna-NM_001180800.1_NCYC1407 cds-NP_010780.1_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:1385265-1386215:+ gene-YDR492W_PE2H3 rna-NM_001180800.1_PE2H3 cds-NP_010780.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:1390839-1391789:+ gene-YDR492W_PE2H4 rna-NM_001180800.1_PE2H4 cds-NP_010780.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:1434924-1435874:+ gene-YDR492W_S288C rna-NM_001180800.1_S288C cds-NP_010780.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000004.1:181265-182215:- gene-YDR492W_SA1 rna-NM_001180800.1_SA1 cds-NP_010780.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:1385975-1386925:+ gene-YDR492W_ThermosaccDry rna-NM_001180800.1_ThermosaccDry cds-NP_010780.1_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:1401710-1402660:+ gene-YDR492W_VR1 rna-NM_001180800.1_VR1 cds-NP_010780.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000008.1:428641-429591:+ gene-YDR492W_ZTW1 rna-NM_001180800.1_ZTW1 cds-NP_010780.1_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:1388779-1389729:+ gene-YDR492W_Sparadoxus rna-NM_001180800.1_Sparadoxus cds-NP_010780.1_Sparadoxus 92.8 100.0 Verified 1 1 1 False True False False False

Additional files