Gene name: IWR1
Reference locus (S288C): YDL115C
Gene biotype: protein_coding
Description: RNA polymerase II nuclear localization protein IWR1; RNA polymerase II transport factor, conserved from yeast to humans; also has a role in transporting RNA polymerase III into the nucleus; interacts with most of the RNAP II subunits; nucleo-cytoplasmic shuttling protein; deletion causes hypersensitivity to K1 killer toxin; protein increases in abundance and relocalizes from nucleus to cytoplasm upon DNA replication stress
Top 10 interactors (score): RPB3 (0.963); RPB5 (0.939); RPB2 (0.93); GPN2 (0.92); RPB11 (0.912); GPN3 (0.909); RPO21 (0.905); RPB10 (0.904); NPA3 (0.893); RPO26 (0.866); RPB4 (0.849); RPB9 (0.827); BUD27 (0.817); RIT1 (0.81); RPO31 (0.799); RPB7 (0.786); RPC10 (0.726); SRP1 (0.676); TFC6 (0.61); RPB8 (0.604)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:238620-239751:- | gene-YDL115C_AKU4011 | rna-NM_001180174.1_AKU4011 | cds-NP_010168.4_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:310203-311334:+ | gene-YDL115C_BG1 | rna-NM_001180174.1_BG1 | cds-NP_010168.4_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:256026-257157:- | gene-YDL115C_Bruggeman | rna-NM_001180174.1_Bruggeman | cds-NP_010168.4_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:252769-253900:- | gene-YDL115C_CAT1 | rna-NM_001180174.1_CAT1 | cds-NP_010168.4_CAT1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:236880-238011:- | gene-YDL115C_CBS1585 | rna-NM_001180174.1_CBS1585 | cds-NP_010168.4_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:253535-254666:- | gene-YDL115C_CBS436 | rna-NM_001180174.1_CBS436 | cds-NP_010168.4_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:235306-236437:- | gene-YDL115C_CBS6412 | rna-NM_001180174.1_CBS6412 | cds-NP_010168.4_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:255041-256172:- | gene-YDL115C_CBS6413 | rna-NM_001180174.1_CBS6413 | cds-NP_010168.4_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:252767-253898:- | gene-YDL115C_CENPK1137D | rna-NM_001180174.1_CENPK1137D | cds-NP_010168.4_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:249645-250776:- | gene-YDL115C_EthanolRed | rna-NM_001180174.1_EthanolRed | cds-NP_010168.4_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:255615-256746:- | gene-YDL115C_FaliES1 | rna-NM_001180174.1_FaliES1 | cds-NP_010168.4_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000010.1:25657-26788:- | gene-YDL115C_JAY291 | rna-NM_001180174.1_JAY291 | cds-NP_010168.4_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:253813-254944:- | gene-YDL115C_MUCL30387 | rna-NM_001180174.1_MUCL30387 | cds-NP_010168.4_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:244571-245702:- | gene-YDL115C_MUCL30388 | rna-NM_001180174.1_MUCL30388 | cds-NP_010168.4_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:237986-239117:- | gene-YDL115C_MUCL39482 | rna-NM_001180174.1_MUCL39482 | cds-NP_010168.4_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:159765-160896:- | gene-YDL115C_MUCL42920 | rna-NM_001180174.1_MUCL42920 | cds-NP_010168.4_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:253918-255049:- | gene-YDL115C_NCIM3186 | rna-NM_001180174.1_NCIM3186 | cds-NP_010168.4_NCIM3186 | 92.3 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:238014-239145:- | gene-YDL115C_NCYC1407 | rna-NM_001180174.1_NCYC1407 | cds-NP_010168.4_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:244768-245899:- | gene-YDL115C_PE2H3 | rna-NM_001180174.1_PE2H3 | cds-NP_010168.4_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:244772-245903:- | gene-YDL115C_PE2H4 | rna-NM_001180174.1_PE2H4 | cds-NP_010168.4_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:253995-255126:- | gene-YDL115C_S288C | rna-NM_001180174.1_S288C | cds-NP_010168.4_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000010.1:179787-180918:+ | gene-YDL115C_SA1 | rna-NM_001180174.1_SA1 | cds-NP_010168.4_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:255126-256257:- | gene-YDL115C_ThermosaccDry | rna-NM_001180174.1_ThermosaccDry | cds-NP_010168.4_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:257230-258361:- | gene-YDL115C_VR1 | rna-NM_001180174.1_VR1 | cds-NP_010168.4_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:253054-254185:- | gene-YDL115C_ZTW1 | rna-NM_001180174.1_ZTW1 | cds-NP_010168.4_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:255207-256339:- | gene-YDL115C_Sparadoxus | rna-NM_001180174.1_Sparadoxus | cds-NP_010168.4_Sparadoxus | 89.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |