ITT1 (YML068W)


Gene profile

Gene name: ITT1
Reference locus (S288C): YML068W
Gene biotype: protein_coding

Description: Protein that modulates the efficiency of translation termination; interacts with translation release factors eRF1 (Sup45p) and eRF3 (Sup35p) in vitro, contains a zinc finger domain characteristic of the TRIAD class of proteins; Belongs to the RBR family

Top 10 interactors (score): SUP35 (0.964); ATP5 (0.961); HEL1 (0.954); SUP45 (0.841); SMM1 (0.839); ECM32 (0.776); APC11 (0.715); YJL055W (0.698); NAM7 (0.695); ETP1 (0.691); BCD1 (0.686); BCP1 (0.668); BSD2 (0.667); ACP1 (0.646); ERG27 (0.643); SNF11 (0.628); PIG2 (0.61); TOM1 (0.603); COF1 (0.601); RPA190 (0.593)

Homologues (species, bitscore): RNF14 (Homo sapiens, 103.2); Rnf14 (Mus musculus, 104.4); rnf14 (Danio rerio, 104.4); rnf14 (Xenopus tropicalis, 101.3); CG11321 (Drosophila melanogaster, 59.7); F56D2.5 (Caenorhabditis elegans, 92.8); NHL8 (Arabidopsis thaliana, 103.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:131285-132679:+ gene-YML068W_AKU4011 rna-NM_001182427.1_AKU4011 cds-NP_013643.1_AKU4011 99.9 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000201.1:343460-344854:- gene-YML068W_BG1 rna-NM_001182427.1_BG1 cds-NP_013643.1_BG1 99.2 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:137427-138821:+ gene-YML068W_Bruggeman rna-NM_001182427.1_Bruggeman cds-NP_013643.1_Bruggeman 99.3 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:139101-140495:+ gene-YML068W_CAT1 rna-NM_001182427.1_CAT1 cds-NP_013643.1_CAT1 99.1 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:131294-132688:+ gene-YML068W_CBS1585 rna-NM_001182427.1_CBS1585 cds-NP_013643.1_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:137195-138589:+ gene-YML068W_CBS436 rna-NM_001182427.1_CBS436 cds-NP_013643.1_CBS436 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:132002-133396:+ gene-YML068W_CBS6412 rna-NM_001182427.1_CBS6412 cds-NP_013643.1_CBS6412 98.9 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:130477-131871:+ gene-YML068W_CBS6413 rna-NM_001182427.1_CBS6413 cds-NP_013643.1_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:132273-133667:+ gene-YML068W_CENPK1137D rna-NM_001182427.1_CENPK1137D cds-NP_013643.1_CENPK1137D 98.9 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005483.1:131558-132952:+ gene-YML068W_EthanolRed rna-NM_001182427.1_EthanolRed cds-NP_013643.1_EthanolRed 99.8 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:132065-133459:+ gene-YML068W_FaliES1 rna-NM_001182427.1_FaliES1 cds-NP_013643.1_FaliES1 99.9 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000366.1:23649-25043:- gene-YML068W_JAY291 rna-NM_001182427.1_JAY291 cds-NP_013643.1_JAY291 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:135957-137351:+ gene-YML068W_MUCL30387 rna-NM_001182427.1_MUCL30387 cds-NP_013643.1_MUCL30387 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:139132-140526:+ gene-YML068W_MUCL30388 rna-NM_001182427.1_MUCL30388 cds-NP_013643.1_MUCL30388 99.2 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:131305-132699:+ gene-YML068W_MUCL39482 rna-NM_001182427.1_MUCL39482 cds-NP_013643.1_MUCL39482 99.1 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:137138-138532:+ gene-YML068W_MUCL42920 rna-NM_001182427.1_MUCL42920 cds-NP_013643.1_MUCL42920 99.3 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:137504-138898:+ gene-YML068W_NCIM3186 rna-NM_001182427.1_NCIM3186 cds-NP_013643.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:132100-133494:+ gene-YML068W_NCYC1407 rna-NM_001182427.1_NCYC1407 cds-NP_013643.1_NCYC1407 98.9 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:137509-138903:+ gene-YML068W_PE2H3 rna-NM_001182427.1_PE2H3 cds-NP_013643.1_PE2H3 99.0 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:137373-138767:+ gene-YML068W_PE2H4 rna-NM_001182427.1_PE2H4 cds-NP_013643.1_PE2H4 99.2 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:137550-138944:+ gene-YML068W_S288C rna-NM_001182427.1_S288C cds-NP_013643.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000041.1:45317-46711:- gene-YML068W_SA1 rna-NM_001182427.1_SA1 cds-NP_013643.1_SA1 99.2 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:131357-132751:+ gene-YML068W_ThermosaccDry rna-NM_001182427.1_ThermosaccDry cds-NP_013643.1_ThermosaccDry 99.9 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:135721-137115:+ gene-YML068W_VR1 rna-NM_001182427.1_VR1 cds-NP_013643.1_VR1 99.1 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000027.1:110894-112288:+ gene-YML068W_ZTW1 rna-NM_001182427.1_ZTW1 cds-NP_013643.1_ZTW1 99.9 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:142474-143868:+ gene-YML068W_Sparadoxus rna-NM_001182427.1_Sparadoxus cds-NP_013643.1_Sparadoxus 88.1 99.9 Verified 1 1 1 False True False False False

Additional files