Gene name: ITR1
Reference locus (S288C): YDR497C
Gene biotype: protein_coding
Description: Myo-inositol transporter; member of the sugar transporter superfamily; expression is repressed by inositol and choline via Opi1p and derepressed via Ino2p and Ino4p; relative distribution to the vacuole increases upon DNA replication stress; ITR1 has a paralog, ITR2, that arose from the whole genome duplication
Top 10 interactors (score): HNM1 (0.946); INO1 (0.939); DIE2 (0.933); CHO1 (0.915); PSD1 (0.885); OPI3 (0.852); ITR2 (0.812); ALG8 (0.78); INO2 (0.775); OPI1 (0.775); INO4 (0.76); CHO2 (0.714); INM1 (0.708); EPT1 (0.692); CPT1 (0.676); FAA2 (0.619); CDS1 (0.618); MUP1 (0.618); CAT2 (0.613); PTC1 (0.613)
Homologues (species, bitscore): SLC2A13 (Homo sapiens, 243.8); Slc2a13 (Mus musculus, 227.6); slc2a13b (Danio rerio, 251.5); ENSXETP00000016917 (Xenopus tropicalis, 253.1); Glut1 (Drosophila melanogaster, 174.5); hmit-1.3 (Caenorhabditis elegans, 228.8); INT1 (Arabidopsis thaliana, 259.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1383699-1385453:- | gene-YDR497C_AKU4011 | rna-NM_001180805.1_AKU4011 | cds-NP_010785.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000073.1:25257-27011:- | gene-YDR497C_BG1 | rna-NM_001180805.1_BG1 | cds-NP_010785.1_BG1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1415045-1416799:- | gene-YDR497C_Bruggeman | rna-NM_001180805.1_Bruggeman | cds-NP_010785.1_Bruggeman | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1392198-1393952:- | gene-YDR497C_CAT1 | rna-NM_001180805.1_CAT1 | cds-NP_010785.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1377941-1379695:- | gene-YDR497C_CBS1585 | rna-NM_001180805.1_CBS1585 | cds-NP_010785.1_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1397294-1399048:- | gene-YDR497C_CBS436 | rna-NM_001180805.1_CBS436 | cds-NP_010785.1_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1373583-1375337:- | gene-YDR497C_CBS6412 | rna-NM_001180805.1_CBS6412 | cds-NP_010785.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1396598-1398352:- | gene-YDR497C_CBS6413 | rna-NM_001180805.1_CBS6413 | cds-NP_010785.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1442407-1444161:- | gene-YDR497C_CENPK1137D | rna-NM_001180805.1_CENPK1137D | cds-NP_010785.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1386989-1388743:- | gene-YDR497C_EthanolRed | rna-NM_001180805.1_EthanolRed | cds-NP_010785.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1390542-1392296:- | gene-YDR497C_FaliES1 | rna-NM_001180805.1_FaliES1 | cds-NP_010785.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000026.1:88791-90545:- | gene-YDR497C_JAY291 | rna-NM_001180805.1_JAY291 | cds-NP_010785.1_JAY291 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1397543-1399297:- | gene-YDR497C_MUCL30387 | rna-NM_001180805.1_MUCL30387 | cds-NP_010785.1_MUCL30387 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1379563-1381317:- | gene-YDR497C_MUCL30388 | rna-NM_001180805.1_MUCL30388 | cds-NP_010785.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1369426-1371180:- | gene-YDR497C_MUCL39482 | rna-NM_001180805.1_MUCL39482 | cds-NP_010785.1_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1312216-1313970:- | gene-YDR497C_MUCL42920 | rna-NM_001180805.1_MUCL42920 | cds-NP_010785.1_MUCL42920 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1443636-1445390:- | gene-YDR497C_NCIM3186 | rna-NM_001180805.1_NCIM3186 | cds-NP_010785.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1383212-1384966:- | gene-YDR497C_NCYC1407 | rna-NM_001180805.1_NCYC1407 | cds-NP_010785.1_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1394058-1395812:- | gene-YDR497C_PE2H3 | rna-NM_001180805.1_PE2H3 | cds-NP_010785.1_PE2H3 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1399633-1401387:- | gene-YDR497C_PE2H4 | rna-NM_001180805.1_PE2H4 | cds-NP_010785.1_PE2H4 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1443713-1445467:- | gene-YDR497C_S288C | rna-NM_001180805.1_S288C | cds-NP_010785.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:171668-173422:+ | gene-YDR497C_SA1 | rna-NM_001180805.1_SA1 | cds-NP_010785.1_SA1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1394764-1396518:- | gene-YDR497C_ThermosaccDry | rna-NM_001180805.1_ThermosaccDry | cds-NP_010785.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1410504-1412258:- | gene-YDR497C_VR1 | rna-NM_001180805.1_VR1 | cds-NP_010785.1_VR1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:437431-439185:- | gene-YDR497C_ZTW1 | rna-NM_001180805.1_ZTW1 | cds-NP_010785.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1397582-1399335:- | gene-YDR497C_Sparadoxus | rna-NM_001180805.1_Sparadoxus | cds-NP_010785.1_Sparadoxus | 90.9 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |