Gene name: ITC1
Reference locus (S288C): YGL133W
Gene biotype: protein_coding
Description: Imitation switch two complex protein 1; Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex; required for repression of a-specific genes, repression of early meiotic genes during mitotic growth, and repression of INO1; similar to mammalian Acf1p, the regulatory subunit of the mammalian ATP-utilizing chromatin assembly and modifying factor (ACF) complex; ITC1 has a paralog, YPL216W, that arose from the whole genome duplication
Top 10 interactors (score): ISW2 (0.999); DPB4 (0.999); DLS1 (0.997); ISW1 (0.985); IOC3 (0.969); IOC2 (0.95); IOC4 (0.927); CHD1 (0.885); NHP10 (0.84); YTA7 (0.837); SNF2 (0.824); NHP6B (0.761); HHF1 (0.754); DPB3 (0.726); SPT16 (0.724); RFX1 (0.723); YGL138C (0.695); HTA2 (0.677); TOP2 (0.674); HAP5 (0.653)
Homologues (species, bitscore): BAZ1A (Homo sapiens, 55.5); Baz1a (Mus musculus, 53.5); baz1b (Danio rerio, 68.9); baz1b (Xenopus tropicalis, 65.5); athp-2 (Caenorhabditis elegans, 50.1); AT5G08630 (Arabidopsis thaliana, 70.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:260520-264314:+ | gene-YGL133W_AKU4011 | rna-NM_001180998.1_AKU4011 | cds-NP_011382.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000132.1:140863-144657:- | gene-YGL133W_BG1 | rna-NM_001180998.1_BG1 | cds-NP_011382.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:263219-267013:+ | gene-YGL133W_Bruggeman | rna-NM_001180998.1_Bruggeman | cds-NP_011382.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:258808-262602:+ | gene-YGL133W_CAT1 | rna-NM_001180998.1_CAT1 | cds-NP_011382.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:263847-267641:+ | gene-YGL133W_CBS1585 | rna-NM_001180998.1_CBS1585 | cds-NP_011382.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:258760-262554:+ | gene-YGL133W_CBS436 | rna-NM_001180998.1_CBS436 | cds-NP_011382.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:249488-253282:+ | gene-YGL133W_CBS6412 | rna-NM_001180998.1_CBS6412 | cds-NP_011382.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:258708-262502:+ | gene-YGL133W_CBS6413 | rna-NM_001180998.1_CBS6413 | cds-NP_011382.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:257966-261760:+ | gene-YGL133W_CENPK1137D | rna-NM_001180998.1_CENPK1137D | cds-NP_011382.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:250232-254026:+ | gene-YGL133W_EthanolRed | rna-NM_001180998.1_EthanolRed | cds-NP_011382.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:252188-255982:+ | gene-YGL133W_FaliES1 | rna-NM_001180998.1_FaliES1 | cds-NP_011382.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000408.1:13209-17003:- | gene-YGL133W_JAY291 | rna-NM_001180998.1_JAY291 | cds-NP_011382.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:260189-263983:+ | gene-YGL133W_MUCL30387 | rna-NM_001180998.1_MUCL30387 | cds-NP_011382.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:263307-267101:+ | gene-YGL133W_MUCL30388 | rna-NM_001180998.1_MUCL30388 | cds-NP_011382.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:260933-264727:+ | gene-YGL133W_MUCL39482 | rna-NM_001180998.1_MUCL39482 | cds-NP_011382.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:264181-267975:+ | gene-YGL133W_MUCL42920 | rna-NM_001180998.1_MUCL42920 | cds-NP_011382.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:257707-261501:+ | gene-YGL133W_NCIM3186 | rna-NM_001180998.1_NCIM3186 | cds-NP_011382.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:252423-256217:+ | gene-YGL133W_NCYC1407 | rna-NM_001180998.1_NCYC1407 | cds-NP_011382.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:253813-257607:+ | gene-YGL133W_PE2H3 | rna-NM_001180998.1_PE2H3 | cds-NP_011382.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:258811-262605:+ | gene-YGL133W_PE2H4 | rna-NM_001180998.1_PE2H4 | cds-NP_011382.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:257707-261501:+ | gene-YGL133W_S288C | rna-NM_001180998.1_S288C | cds-NP_011382.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000064.1:2592-6386:+ | gene-YGL133W_SA1 | rna-NM_001180998.1_SA1 | cds-NP_011382.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:252417-256211:+ | gene-YGL133W_ThermosaccDry | rna-NM_001180998.1_ThermosaccDry | cds-NP_011382.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:362545-366339:+ | gene-YGL133W_VR1 | rna-NM_001180998.1_VR1 | cds-NP_011382.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:249996-253790:+ | gene-YGL133W_ZTW1 | rna-NM_001180998.1_ZTW1 | cds-NP_011382.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:256025-259816:+ | gene-YGL133W_Sparadoxus | rna-NM_001180998.1_Sparadoxus | cds-NP_011382.1_Sparadoxus | 88.3 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |