Gene name: ISW2
Reference locus (S288C): YOR304W
Gene biotype: protein_coding
Description: ISWI chromatin-remodeling complex ATPase ISW2; ATP-dependent DNA translocase involved in chromatin remodeling; ATPase component that, with Itc1p, forms a complex required for repression of a-specific genes, INO1, and early meiotic genes during mitotic growth; the Isw2 complex exhibits basal levels of chromatin binding throughout the genome as well as target-specific chromatin interactions; targeted by Ume6p- and Sua7p-dependent DNA looping to many loci genome-wide
Top 10 interactors (score): ITC1 (0.999); DPB4 (0.997); DLS1 (0.996); HAT2 (0.992); ISW1 (0.975); HHF1 (0.932); MCM3 (0.92); IOC2 (0.906); SPP1 (0.902); CHD1 (0.899); NHP10 (0.888); RPD3 (0.883); IOC4 (0.875); HTZ1 (0.875); MSI1 (0.872); RAD51 (0.865); HAP5 (0.858); CSM4 (0.85); IPP1 (0.832); IOC3 (0.821)
Homologues (species, bitscore): SMARCA5 (Homo sapiens, 983.8); Smarca5 (Mus musculus, 981.9); smarca5 (Danio rerio, 967.2); smarca1 (Xenopus tropicalis, 973.4); Iswi (Drosophila melanogaster, 954.5); isw-1 (Caenorhabditis elegans, 916.0); CHR11 (Arabidopsis thaliana, 866.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:874981-878343:+ | gene-YOR304W_AKU4011 | rna-NM_001183724.1_AKU4011 | cds-NP_014948.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:276996-280361:+ | gene-YOR304W_BG1 | rna-NM_001183724.1_BG1 | cds-NP_014948.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:860405-863773:+ | gene-YOR304W_Bruggeman | rna-NM_001183724.1_Bruggeman | cds-NP_014948.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:861147-864512:+ | gene-YOR304W_CAT1 | rna-NM_001183724.1_CAT1 | cds-NP_014948.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:858791-862153:+ | gene-YOR304W_CBS1585 | rna-NM_001183724.1_CBS1585 | cds-NP_014948.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:856640-860005:+ | gene-YOR304W_CBS436 | rna-NM_001183724.1_CBS436 | cds-NP_014948.1_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:854508-857870:+ | gene-YOR304W_CBS6412 | rna-NM_001183724.1_CBS6412 | cds-NP_014948.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:863636-866998:+ | gene-YOR304W_CBS6413 | rna-NM_001183724.1_CBS6413 | cds-NP_014948.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:884302-887664:+ | gene-YOR304W_CENPK1137D | rna-NM_001183724.1_CENPK1137D | cds-NP_014948.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:850890-854252:+ | gene-YOR304W_EthanolRed | rna-NM_001183724.1_EthanolRed | cds-NP_014948.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:856510-859872:+ | gene-YOR304W_FaliES1 | rna-NM_001183724.1_FaliES1 | cds-NP_014948.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000078.1:143372-146737:- | gene-YOR304W_JAY291 | rna-NM_001183724.1_JAY291 | cds-NP_014948.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:864652-868017:+ | gene-YOR304W_MUCL30387 | rna-NM_001183724.1_MUCL30387 | cds-NP_014948.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:872652-876014:+ | gene-YOR304W_MUCL30388 | rna-NM_001183724.1_MUCL30388 | cds-NP_014948.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:865337-868699:+ | gene-YOR304W_MUCL39482 | rna-NM_001183724.1_MUCL39482 | cds-NP_014948.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:874837-878199:+ | gene-YOR304W_MUCL42920 | rna-NM_001183724.1_MUCL42920 | cds-NP_014948.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:884403-887765:+ | gene-YOR304W_NCIM3186 | rna-NM_001183724.1_NCIM3186 | cds-NP_014948.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:866346-869708:+ | gene-YOR304W_NCYC1407 | rna-NM_001183724.1_NCYC1407 | cds-NP_014948.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:864580-867945:+ | gene-YOR304W_PE2H3 | rna-NM_001183724.1_PE2H3 | cds-NP_014948.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:880932-884297:+ | gene-YOR304W_PE2H4 | rna-NM_001183724.1_PE2H4 | cds-NP_014948.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:884514-887876:+ | gene-YOR304W_S288C | rna-NM_001183724.1_S288C | cds-NP_014948.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000090.1:1864-5229:- | gene-YOR304W_SA1 | rna-NM_001183724.1_SA1 | cds-NP_014948.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:855696-859058:+ | gene-YOR304W_ThermosaccDry | rna-NM_001183724.1_ThermosaccDry | cds-NP_014948.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:919023-922388:+ | gene-YOR304W_VR1 | rna-NM_001183724.1_VR1 | cds-NP_014948.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:588577-591939:+ | gene-YOR304W_ZTW1 | rna-NM_001183724.1_ZTW1 | cds-NP_014948.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:862789-866151:+ | gene-YOR304W_Sparadoxus | rna-NM_001183724.1_Sparadoxus | cds-NP_014948.1_Sparadoxus | 90.9 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |