Gene name: ISW1
Reference locus (S288C): YBR245C
Gene biotype: protein_coding
Description: ISWI chromatin-remodeling complex ATPase ISW1; ATPase subunit of imitation-switch (ISWI) class chromatin remodelers; with Ioc3p forms Isw1a complex involved in repression of transcription initiation; with Ioc2p and Ioc4p forms Isw1b complex involved in regulation of transcription elongation; Isw1b recruited to ORFs by H3K36 methylation and acts with Chd1p to prevent trans-histone exchange over coding regions; Isw1p import into nucleus depends on C-terminal bipartite nuclear targeting signal KRIR X19 KKAK
Top 10 interactors (score): IOC3 (0.999); IOC2 (0.997); IOC4 (0.993); HAT2 (0.992); ITC1 (0.985); DPB4 (0.98); ISW2 (0.975); ESC8 (0.965); CHD1 (0.955); HHF1 (0.955); HTZ1 (0.943); MCM3 (0.943); NPL6 (0.938); RSC8 (0.935); HHT1 (0.934); RSC2 (0.923); DLS1 (0.916); SPT16 (0.916); HHT2 (0.913); SPP1 (0.902)
Homologues (species, bitscore): SMARCA1 (Homo sapiens, 943.7); Smarca5 (Mus musculus, 939.9); LOC559803 (Danio rerio, 940.3); smarca1 (Xenopus tropicalis, 941.4); Iswi (Drosophila melanogaster, 910.6); isw-1 (Caenorhabditis elegans, 924.1); CHR17 (Arabidopsis thaliana, 837.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:692461-695850:- | gene-YBR245C_AKU4011 | rna-NM_001178593.1_AKU4011 | cds-NP_009804.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000066.1:63468-66857:- | gene-YBR245C_BG1 | rna-NM_001178593.1_BG1 | cds-NP_009804.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:693602-696991:- | gene-YBR245C_Bruggeman | rna-NM_001178593.1_Bruggeman | cds-NP_009804.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:697091-700480:- | gene-YBR245C_CAT1 | rna-NM_001178593.1_CAT1 | cds-NP_009804.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:684027-687416:- | gene-YBR245C_CBS1585 | rna-NM_001178593.1_CBS1585 | cds-NP_009804.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:690446-693835:- | gene-YBR245C_CBS436 | rna-NM_001178593.1_CBS436 | cds-NP_009804.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:778632-782021:- | gene-YBR245C_CBS6412 | rna-NM_001178593.1_CBS6412 | cds-NP_009804.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:690076-693465:- | gene-YBR245C_CBS6413 | rna-NM_001178593.1_CBS6413 | cds-NP_009804.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:702063-705450:- | gene-YBR245C_CENPK1137D | rna-NM_001178593.1_CENPK1137D | cds-NP_009804.1_CENPK1137D | 99.9 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:815483-818873:- | gene-YBR245C_EthanolRed | rna-NM_001178593.1_EthanolRed | cds-NP_009804.1_EthanolRed | 99.5 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:708830-712220:- | gene-YBR245C_FaliES1 | rna-NM_001178593.1_FaliES1 | cds-NP_009804.1_FaliES1 | 99.5 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000067.1:91844-95233:+ | gene-YBR245C_JAY291 | rna-NM_001178593.1_JAY291 | cds-NP_009804.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:695645-699034:- | gene-YBR245C_MUCL30387 | rna-NM_001178593.1_MUCL30387 | cds-NP_009804.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:712728-716117:- | gene-YBR245C_MUCL30388 | rna-NM_001178593.1_MUCL30388 | cds-NP_009804.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:682334-685723:- | gene-YBR245C_MUCL39482 | rna-NM_001178593.1_MUCL39482 | cds-NP_009804.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:692180-695569:- | gene-YBR245C_MUCL42920 | rna-NM_001178593.1_MUCL42920 | cds-NP_009804.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:707947-711336:- | gene-YBR245C_NCIM3186 | rna-NM_001178593.1_NCIM3186 | cds-NP_009804.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:684223-687612:- | gene-YBR245C_NCYC1407 | rna-NM_001178593.1_NCYC1407 | cds-NP_009804.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:707329-710718:- | gene-YBR245C_PE2H3 | rna-NM_001178593.1_PE2H3 | cds-NP_009804.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:705005-708394:- | gene-YBR245C_PE2H4 | rna-NM_001178593.1_PE2H4 | cds-NP_009804.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:708150-711539:- | gene-YBR245C_S288C | rna-NM_001178593.1_S288C | cds-NP_009804.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000019.1:63290-66679:- | gene-YBR245C_SA1 | rna-NM_001178593.1_SA1 | cds-NP_009804.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:707822-711212:- | gene-YBR245C_ThermosaccDry | rna-NM_001178593.1_ThermosaccDry | cds-NP_009804.1_ThermosaccDry | 99.5 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:688039-691428:- | gene-YBR245C_VR1 | rna-NM_001178593.1_VR1 | cds-NP_009804.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:680682-684071:- | gene-YBR245C_ZTW1 | rna-NM_001178593.1_ZTW1 | cds-NP_009804.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:724651-728045:- | gene-YBR245C_Sparadoxus | rna-NM_001178593.1_Sparadoxus | cds-NP_009804.1_Sparadoxus | 90.4 | 99.7 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |