Gene name: IST3
Reference locus (S288C): YIR005W
Gene biotype: protein_coding
Description: Rna-binding motif protein, x-linked 2; Component of the U2 snRNP; required for the first catalytic step of splicing and for spliceosomal assembly; interacts with Rds3p and is required for Mer1p-activated splicing; diploid mutants have a specific defect in MATa1 pre-mRNA splicing which leads to haploid gene expression in diploids; Belongs to the IST3 family
Top 10 interactors (score): CEF1 (0.999); CUS1 (0.999); SNU66 (0.999); HSH49 (0.999); PML1 (0.999); HSH155 (0.999); RDS3 (0.999); PRP19 (0.999); HUB1 (0.999); LEA1 (0.999); CWC2 (0.999); RSE1 (0.999); BUD13 (0.999); BUD31 (0.998); YSF3 (0.998); PRP21 (0.997); CWC21 (0.997); PRP11 (0.994); PRP2 (0.994); CWC22 (0.993)
Homologues (species, bitscore): RBMX2 (Homo sapiens, 132.1); Rbmx2 (Mus musculus, 128.6); rbmx2 (Danio rerio, 122.5); rbmx2 (Xenopus tropicalis, 122.9); CG10466 (Drosophila melanogaster, 119.8); C30B5.4 (Caenorhabditis elegans, 114.4); AT3G47120 (Arabidopsis thaliana, 125.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:364280-364726:+ | gene-YIR005W_AKU4011 | rna-NM_001179527.1_AKU4011 | cds-NP_012270.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000072.1:61879-62325:- | gene-YIR005W_BG1 | rna-NM_001179527.1_BG1 | cds-NP_012270.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:368717-369163:+ | gene-YIR005W_Bruggeman | rna-NM_001179527.1_Bruggeman | cds-NP_012270.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:355383-355829:+ | gene-YIR005W_CAT1 | rna-NM_001179527.1_CAT1 | cds-NP_012270.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:364297-364743:+ | gene-YIR005W_CBS1585 | rna-NM_001179527.1_CBS1585 | cds-NP_012270.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:356949-357395:+ | gene-YIR005W_CBS436 | rna-NM_001179527.1_CBS436 | cds-NP_012270.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005335.1:359800-360246:+ | gene-YIR005W_CBS6412 | rna-NM_001179527.1_CBS6412 | cds-NP_012270.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:356377-356823:+ | gene-YIR005W_CBS6413 | rna-NM_001179527.1_CBS6413 | cds-NP_012270.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:356950-357396:+ | gene-YIR005W_CENPK1137D | rna-NM_001179527.1_CENPK1137D | cds-NP_012270.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:347354-347800:+ | gene-YIR005W_EthanolRed | rna-NM_001179527.1_EthanolRed | cds-NP_012270.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:365597-366043:+ | gene-YIR005W_FaliES1 | rna-NM_001179527.1_FaliES1 | cds-NP_012270.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000009.1:25461-25907:- | gene-YIR005W_JAY291 | rna-NM_001179527.1_JAY291 | cds-NP_012270.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:365922-366368:+ | gene-YIR005W_MUCL30387 | rna-NM_001179527.1_MUCL30387 | cds-NP_012270.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:362667-363113:+ | gene-YIR005W_MUCL30388 | rna-NM_001179527.1_MUCL30388 | cds-NP_012270.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:364934-365380:+ | gene-YIR005W_MUCL39482 | rna-NM_001179527.1_MUCL39482 | cds-NP_012270.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:368530-368976:+ | gene-YIR005W_MUCL42920 | rna-NM_001179527.1_MUCL42920 | cds-NP_012270.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:364889-365335:+ | gene-YIR005W_NCIM3186 | rna-NM_001179527.1_NCIM3186 | cds-NP_012270.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:369179-369625:+ | gene-YIR005W_NCYC1407 | rna-NM_001179527.1_NCYC1407 | cds-NP_012270.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:358961-359407:+ | gene-YIR005W_PE2H3 | rna-NM_001179527.1_PE2H3 | cds-NP_012270.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:353667-354113:+ | gene-YIR005W_PE2H4 | rna-NM_001179527.1_PE2H4 | cds-NP_012270.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:364889-365335:+ | gene-YIR005W_S288C | rna-NM_001179527.1_S288C | cds-NP_012270.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000066.1:39743-40189:+ | gene-YIR005W_SA1 | rna-NM_001179527.1_SA1 | cds-NP_012270.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:363703-364149:+ | gene-YIR005W_ThermosaccDry | rna-NM_001179527.1_ThermosaccDry | cds-NP_012270.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:359522-359968:+ | gene-YIR005W_VR1 | rna-NM_001179527.1_VR1 | cds-NP_012270.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000019.1:337699-338145:+ | gene-YIR005W_ZTW1 | rna-NM_001179527.1_ZTW1 | cds-NP_012270.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:359036-359485:+ | gene-YIR005W_Sparadoxus | rna-NM_001179527.1_Sparadoxus | cds-NP_012270.1_Sparadoxus | 89.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |