Gene name: IST1
Reference locus (S288C): YNL265C
Gene biotype: protein_coding
Description: Vacuolar protein sorting-associated protein IST1; Protein with positive role in the multivesicular body sorting pathway; functions and forms a complex with Did2p; recruitment to endosomes is mediated by the Vps2p-Vps24p subcomplex of ESCRT-III; also interacts with Vps4p; Belongs to the IST1 family
Top 10 interactors (score): DID2 (0.999); VPS60 (0.999); VPS4 (0.999); VPS24 (0.997); DID4 (0.995); SNF7 (0.992); VPS20 (0.979); VTA1 (0.966); CHM7 (0.956); MIM2 (0.943); VPS28 (0.936); VPS27 (0.909); BRO1 (0.903); VPS25 (0.897); RIM13 (0.892); VPS36 (0.826); GCD1 (0.81); DOA4 (0.79); SUI3 (0.776); GCD2 (0.771)
Homologues (species, bitscore): IST1 (Homo sapiens, 103.6); Ist1 (Mus musculus, 102.4); ist1 (Danio rerio, 100.5); ist1 (Xenopus tropicalis, 107.1); CG10103 (Drosophila melanogaster, 94.7); K10C8.3 (Caenorhabditis elegans, 104.4); AT1G25420 (Arabidopsis thaliana, 82.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:138056-139057:- | gene-YNL265C_AKU4011 | rna-NM_001183103.1_AKU4011 | cds-NP_014134.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:42015-43016:- | gene-YNL265C_BG1 | rna-NM_001183103.1_BG1 | cds-NP_014134.1_BG1 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:147880-148881:- | gene-YNL265C_Bruggeman | rna-NM_001183103.1_Bruggeman | cds-NP_014134.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:155176-156177:- | gene-YNL265C_CAT1 | rna-NM_001183103.1_CAT1 | cds-NP_014134.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:138456-139457:- | gene-YNL265C_CBS1585 | rna-NM_001183103.1_CBS1585 | cds-NP_014134.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:133554-134555:- | gene-YNL265C_CBS436 | rna-NM_001183103.1_CBS436 | cds-NP_014134.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:134868-135869:- | gene-YNL265C_CBS6412 | rna-NM_001183103.1_CBS6412 | cds-NP_014134.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:135149-136150:- | gene-YNL265C_CBS6413 | rna-NM_001183103.1_CBS6413 | cds-NP_014134.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:138101-139102:- | gene-YNL265C_CENPK1137D | rna-NM_001183103.1_CENPK1137D | cds-NP_014134.1_CENPK1137D | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:135702-136703:- | gene-YNL265C_EthanolRed | rna-NM_001183103.1_EthanolRed | cds-NP_014134.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:130439-131440:- | gene-YNL265C_FaliES1 | rna-NM_001183103.1_FaliES1 | cds-NP_014134.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000082.1:41613-42614:- | gene-YNL265C_JAY291 | rna-NM_001183103.1_JAY291 | cds-NP_014134.1_JAY291 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:143666-144667:- | gene-YNL265C_MUCL30387 | rna-NM_001183103.1_MUCL30387 | cds-NP_014134.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:142246-143247:- | gene-YNL265C_MUCL30388 | rna-NM_001183103.1_MUCL30388 | cds-NP_014134.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:135946-136947:- | gene-YNL265C_MUCL39482 | rna-NM_001183103.1_MUCL39482 | cds-NP_014134.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:138215-139216:- | gene-YNL265C_MUCL42920 | rna-NM_001183103.1_MUCL42920 | cds-NP_014134.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:144249-145250:- | gene-YNL265C_NCIM3186 | rna-NM_001183103.1_NCIM3186 | cds-NP_014134.1_NCIM3186 | 98.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:138047-139048:- | gene-YNL265C_NCYC1407 | rna-NM_001183103.1_NCYC1407 | cds-NP_014134.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:134949-135950:- | gene-YNL265C_PE2H3 | rna-NM_001183103.1_PE2H3 | cds-NP_014134.1_PE2H3 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:134337-135338:- | gene-YNL265C_PE2H4 | rna-NM_001183103.1_PE2H4 | cds-NP_014134.1_PE2H4 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:144280-145281:- | gene-YNL265C_S288C | rna-NM_001183103.1_S288C | cds-NP_014134.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000034.1:41683-42684:- | gene-YNL265C_SA1 | rna-NM_001183103.1_SA1 | cds-NP_014134.1_SA1 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:131296-132297:- | gene-YNL265C_ThermosaccDry | rna-NM_001183103.1_ThermosaccDry | cds-NP_014134.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:150208-151209:- | gene-YNL265C_VR1 | rna-NM_001183103.1_VR1 | cds-NP_014134.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:41632-42633:- | gene-YNL265C_ZTW1 | rna-NM_001183103.1_ZTW1 | cds-NP_014134.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:141492-142494:- | gene-YNL265C_Sparadoxus | rna-NM_001183103.1_Sparadoxus | cds-NP_014134.1_Sparadoxus | 87.8 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |