Gene name: ISN1
Reference locus (S288C): YOR155C
Gene biotype: protein_coding
Description: IMP-specific 5'-nucleotidase 1; Inosine 5'-monophosphate (IMP)-specific 5'-nucleotidase; catalyzes the breakdown of IMP to inosine; responsible for production of nicotinamide riboside and nicotinic acid riboside; expression positively regulated by nicotinic acid and glucose availability; does not show similarity to known 5'-nucleotidases from other organisms; Belongs to the ISN1 family
Top 10 interactors (score): PNP1 (0.994); SDT1 (0.989); URH1 (0.988); NMA2 (0.986); NMA1 (0.986); AMD1 (0.985); HPT1 (0.973); NPY1 (0.973); AAH1 (0.948); ADE16 (0.947); ADE12 (0.946); BNA6 (0.945); IMD3 (0.943); NPT1 (0.916); ADE17 (0.906); YND1 (0.904); IMD2 (0.901); IMD4 (0.901); HAM1 (0.9); POF1 (0.9)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:624252-625604:- | gene-YOR155C_AKU4011 | rna-NM_001183574.3_AKU4011 | cds-NP_014798.3_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:26009-27361:- | gene-YOR155C_BG1 | rna-NM_001183574.3_BG1 | cds-NP_014798.3_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:608326-609678:- | gene-YOR155C_Bruggeman | rna-NM_001183574.3_Bruggeman | cds-NP_014798.3_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:608344-609696:- | gene-YOR155C_CAT1 | rna-NM_001183574.3_CAT1 | cds-NP_014798.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:606753-608105:- | gene-YOR155C_CBS1585 | rna-NM_001183574.3_CBS1585 | cds-NP_014798.3_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:605048-606400:- | gene-YOR155C_CBS436 | rna-NM_001183574.3_CBS436 | cds-NP_014798.3_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:604365-605717:- | gene-YOR155C_CBS6412 | rna-NM_001183574.3_CBS6412 | cds-NP_014798.3_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:613040-614392:- | gene-YOR155C_CBS6413 | rna-NM_001183574.3_CBS6413 | cds-NP_014798.3_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:626384-627736:- | gene-YOR155C_CENPK1137D | rna-NM_001183574.3_CENPK1137D | cds-NP_014798.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:600464-601816:- | gene-YOR155C_EthanolRed | rna-NM_001183574.3_EthanolRed | cds-NP_014798.3_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:605317-606669:- | gene-YOR155C_FaliES1 | rna-NM_001183574.3_FaliES1 | cds-NP_014798.3_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000070.1:36871-38223:+ | gene-YOR155C_JAY291 | rna-NM_001183574.3_JAY291 | cds-NP_014798.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:613133-614485:- | gene-YOR155C_MUCL30387 | rna-NM_001183574.3_MUCL30387 | cds-NP_014798.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:619890-621242:- | gene-YOR155C_MUCL30388 | rna-NM_001183574.3_MUCL30388 | cds-NP_014798.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:614594-615946:- | gene-YOR155C_MUCL39482 | rna-NM_001183574.3_MUCL39482 | cds-NP_014798.3_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:624016-625368:- | gene-YOR155C_MUCL42920 | rna-NM_001183574.3_MUCL42920 | cds-NP_014798.3_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:626517-627869:- | gene-YOR155C_NCIM3186 | rna-NM_001183574.3_NCIM3186 | cds-NP_014798.3_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:614680-616032:- | gene-YOR155C_NCYC1407 | rna-NM_001183574.3_NCYC1407 | cds-NP_014798.3_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:613189-614541:- | gene-YOR155C_PE2H3 | rna-NM_001183574.3_PE2H3 | cds-NP_014798.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:623566-624918:- | gene-YOR155C_PE2H4 | rna-NM_001183574.3_PE2H4 | cds-NP_014798.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:626628-627980:- | gene-YOR155C_S288C | rna-NM_001183574.3_S288C | cds-NP_014798.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000006.1:43175-44527:- | gene-YOR155C_SA1 | rna-NM_001183574.3_SA1 | cds-NP_014798.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:604500-605852:- | gene-YOR155C_ThermosaccDry | rna-NM_001183574.3_ThermosaccDry | cds-NP_014798.3_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:668189-669541:- | gene-YOR155C_VR1 | rna-NM_001183574.3_VR1 | cds-NP_014798.3_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:337953-339305:- | gene-YOR155C_ZTW1 | rna-NM_001183574.3_ZTW1 | cds-NP_014798.3_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:609618-610970:- | gene-YOR155C_Sparadoxus | rna-NM_001183574.3_Sparadoxus | cds-NP_014798.3_Sparadoxus | 89.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |