Gene name: ISA2
Reference locus (S288C): YPR067W
Gene biotype: protein_coding
Description: Iron-sulfur assembly protein 2; Protein required for maturation of mitochondrial [4Fe-4S] proteins; functions in a complex with Isa1p and possibly Iba57p; localizes to the mitochondrial intermembrane space, overexpression of ISA2 suppresses grx5 mutations
Top 10 interactors (score): ISA1 (0.999); GRX5 (0.999); IBA57 (0.998); JAC1 (0.998); NFU1 (0.991); ISU1 (0.981); LIP5 (0.978); NFS1 (0.975); YAH1 (0.974); ISD11 (0.964); BOL3 (0.961); ISU2 (0.961); YFH1 (0.942); ATM1 (0.941); MGE1 (0.928); SSQ1 (0.915); BOL1 (0.902); FOX2 (0.882); RPB11 (0.881); TUM1 (0.828)
Homologues (species, bitscore): ISCA2 (Homo sapiens, 70.5); Isca2 (Mus musculus, 70.5); ISCA2 (Danio rerio, 63.2); ISCA2 (Xenopus tropicalis, 70.1); CG13623 (Drosophila melanogaster, 67.8); Y54G11A.9 (Caenorhabditis elegans, 70.1); AT5G03905 (Arabidopsis thaliana, 56.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:653898-654455:+ | gene-YPR067W_AKU4011 | rna-NM_001184164.1_AKU4011 | cds-NP_015392.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:243236-243793:- | gene-YPR067W_BG1 | rna-NM_001184164.1_BG1 | cds-NP_015392.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:731565-732122:+ | gene-YPR067W_Bruggeman | rna-NM_001184164.1_Bruggeman | cds-NP_015392.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:775009-775566:+ | gene-YPR067W_CAT1 | rna-NM_001184164.1_CAT1 | cds-NP_015392.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:657586-658143:+ | gene-YPR067W_CBS1585 | rna-NM_001184164.1_CBS1585 | cds-NP_015392.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:671951-672508:+ | gene-YPR067W_CBS436 | rna-NM_001184164.1_CBS436 | cds-NP_015392.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:661333-661890:+ | gene-YPR067W_CBS6412 | rna-NM_001184164.1_CBS6412 | cds-NP_015392.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:654532-655089:+ | gene-YPR067W_CBS6413 | rna-NM_001184164.1_CBS6413 | cds-NP_015392.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:682183-682740:+ | gene-YPR067W_CENPK1137D | rna-NM_001184164.1_CENPK1137D | cds-NP_015392.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:981092-981649:+ | gene-YPR067W_EthanolRed | rna-NM_001184164.1_EthanolRed | cds-NP_015392.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:659729-660286:+ | gene-YPR067W_FaliES1 | rna-NM_001184164.1_FaliES1 | cds-NP_015392.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000446.1:31671-32228:+ | gene-YPR067W_JAY291 | rna-NM_001184164.1_JAY291 | cds-NP_015392.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:672825-673382:+ | gene-YPR067W_MUCL30387 | rna-NM_001184164.1_MUCL30387 | cds-NP_015392.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:671530-672087:+ | gene-YPR067W_MUCL30388 | rna-NM_001184164.1_MUCL30388 | cds-NP_015392.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:650843-651400:+ | gene-YPR067W_MUCL39482 | rna-NM_001184164.1_MUCL39482 | cds-NP_015392.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:713666-714223:+ | gene-YPR067W_MUCL42920 | rna-NM_001184164.1_MUCL42920 | cds-NP_015392.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:682203-682760:+ | gene-YPR067W_NCIM3186 | rna-NM_001184164.1_NCIM3186 | cds-NP_015392.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:658771-659328:+ | gene-YPR067W_NCYC1407 | rna-NM_001184164.1_NCYC1407 | cds-NP_015392.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:664974-665531:+ | gene-YPR067W_PE2H3 | rna-NM_001184164.1_PE2H3 | cds-NP_015392.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:664622-665179:+ | gene-YPR067W_PE2H4 | rna-NM_001184164.1_PE2H4 | cds-NP_015392.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:682220-682777:+ | gene-YPR067W_S288C | rna-NM_001184164.1_S288C | cds-NP_015392.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000026.1:17913-18470:- | gene-YPR067W_SA1 | rna-NM_001184164.1_SA1 | cds-NP_015392.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:659504-660061:+ | gene-YPR067W_ThermosaccDry | rna-NM_001184164.1_ThermosaccDry | cds-NP_015392.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:675648-676205:+ | gene-YPR067W_VR1 | rna-NM_001184164.1_VR1 | cds-NP_015392.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:658727-659284:+ | gene-YPR067W_ZTW1 | rna-NM_001184164.1_ZTW1 | cds-NP_015392.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:659497-660054:+ | gene-YPR067W_Sparadoxus | rna-NM_001184164.1_Sparadoxus | cds-NP_015392.1_Sparadoxus | 87.1 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |