Gene name: IRR1
Reference locus (S288C): YIL026C
Gene biotype: protein_coding
Description: Subunit of the cohesin complex; which is required for sister chromatid cohesion during mitosis and meiosis and interacts with centromeres and chromosome arms; relocalizes to the cytosol in response to hypoxia; essential for viability; Belongs to the SCC3 family
Top 10 interactors (score): PDS5 (0.999); SCC2 (0.999); ECO1 (0.999); SMC1 (0.999); MCD1 (0.999); SMC3 (0.999); SMC4 (0.998); CDC5 (0.998); SMC5 (0.997); ESP1 (0.997); SMC6 (0.994); SMC2 (0.993); RAD61 (0.957); POL1 (0.941); CTF4 (0.922); NSE4 (0.921); MMS21 (0.919); SCC4 (0.919); POL2 (0.916); MCM5 (0.914)
Homologues (species, bitscore): STAG1 (Homo sapiens, 110.9); Stag1 (Mus musculus, 110.2); stag1a (Danio rerio, 116.3); stag1 (Xenopus tropicalis, 110.5); SA (Drosophila melanogaster, 99.8); scc-3 (Caenorhabditis elegans, 77.0); SCC3 (Arabidopsis thaliana, 82.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:302932-306384:- | gene-YIL026C_AKU4011 | rna-NM_001179376.1_AKU4011 | cds-NP_012238.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000164.1:162757-166209:- | gene-YIL026C_BG1 | rna-NM_001179376.1_BG1 | cds-NP_012238.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:308074-311526:- | gene-YIL026C_Bruggeman | rna-NM_001179376.1_Bruggeman | cds-NP_012238.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:295491-298943:- | gene-YIL026C_CAT1 | rna-NM_001179376.1_CAT1 | cds-NP_012238.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:303021-306473:- | gene-YIL026C_CBS1585 | rna-NM_001179376.1_CBS1585 | cds-NP_012238.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:296455-299907:- | gene-YIL026C_CBS436 | rna-NM_001179376.1_CBS436 | cds-NP_012238.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005335.1:298553-302005:- | gene-YIL026C_CBS6412 | rna-NM_001179376.1_CBS6412 | cds-NP_012238.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:294937-298389:- | gene-YIL026C_CBS6413 | rna-NM_001179376.1_CBS6413 | cds-NP_012238.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:296386-299838:- | gene-YIL026C_CENPK1137D | rna-NM_001179376.1_CENPK1137D | cds-NP_012238.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:285899-289351:- | gene-YIL026C_EthanolRed | rna-NM_001179376.1_EthanolRed | cds-NP_012238.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:303810-307262:- | gene-YIL026C_FaliES1 | rna-NM_001179376.1_FaliES1 | cds-NP_012238.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000098.1:9726-13178:+ | gene-YIL026C_JAY291 | rna-NM_001179376.1_JAY291 | cds-NP_012238.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:304924-308376:- | gene-YIL026C_MUCL30387 | rna-NM_001179376.1_MUCL30387 | cds-NP_012238.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:301029-304481:- | gene-YIL026C_MUCL30388 | rna-NM_001179376.1_MUCL30388 | cds-NP_012238.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:303612-307064:- | gene-YIL026C_MUCL39482 | rna-NM_001179376.1_MUCL39482 | cds-NP_012238.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:306740-310192:- | gene-YIL026C_MUCL42920 | rna-NM_001179376.1_MUCL42920 | cds-NP_012238.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:304477-307929:- | gene-YIL026C_NCIM3186 | rna-NM_001179376.1_NCIM3186 | cds-NP_012238.1_NCIM3186 | 97.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:307885-311337:- | gene-YIL026C_NCYC1407 | rna-NM_001179376.1_NCYC1407 | cds-NP_012238.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:299526-302978:- | gene-YIL026C_PE2H3 | rna-NM_001179376.1_PE2H3 | cds-NP_012238.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:294232-297684:- | gene-YIL026C_PE2H4 | rna-NM_001179376.1_PE2H4 | cds-NP_012238.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:304477-307929:- | gene-YIL026C_S288C | rna-NM_001179376.1_S288C | cds-NP_012238.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000031.1:16605-20057:+ | gene-YIL026C_SA1 | rna-NM_001179376.1_SA1 | cds-NP_012238.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:302479-305931:- | gene-YIL026C_ThermosaccDry | rna-NM_001179376.1_ThermosaccDry | cds-NP_012238.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:299114-302566:- | gene-YIL026C_VR1 | rna-NM_001179376.1_VR1 | cds-NP_012238.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000019.1:276899-280351:- | gene-YIL026C_ZTW1 | rna-NM_001179376.1_ZTW1 | cds-NP_012238.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:297616-301080:- | gene-YIL026C_Sparadoxus | rna-NM_001179376.1_Sparadoxus | cds-NP_012238.1_Sparadoxus | 89.7 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |