Gene name: IRC7
Reference locus (S288C): YFR055W
Gene biotype: protein_coding
Description: Putative cystathionine beta-lyase; Beta-lyase involved in the production of thiols; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner and by copper levels in a Mac1-dependent manner; Belongs to the trans-sulfuration enzymes family
Top 10 interactors (score): TUM1 (0.974); MCY1 (0.954); CYS4 (0.951); YML082W (0.942); MET6 (0.937); SAH1 (0.934); CYS3 (0.929); AAT1 (0.923); YLL058W (0.921); SAM4 (0.92); AAT2 (0.918); MHT1 (0.915); MET17 (0.908); STR2 (0.9); STR3 (0.882); CAB2 (0.872); GSH1 (0.864); THR1 (0.858); CTT1 (0.854); REE1 (0.853)
Homologues (species, bitscore): CTH (Homo sapiens, 166.8); Cth (Mus musculus, 155.2); cthl (Danio rerio, 158.7); cth (Xenopus tropicalis, 152.5); Eip55E (Drosophila melanogaster, 156.8); cth-1 (Caenorhabditis elegans, 169.9); MTO1 (Arabidopsis thaliana, 146.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005300.1:254338-255360:+ | gene-YFR055W_AKU4011 | rna-NM_001180021.1_AKU4011 | cds-NP_116714.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000071.1:5541-6566:- | gene-YFR055W_BG1 | rna-NM_001180021.1_BG1 | cds-NP_116714.1_BG1 | 85.8 | 100.0 | Mismatch | 1 | 1 | 0 | False | False | False | True | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005508.1:258005-259027:+ | gene-YFR055W_Bruggeman | rna-NM_001180021.1_Bruggeman | cds-NP_116714.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005524.1:260069-261094:+ | gene-YFR055W_CAT1 | rna-NM_001180021.1_CAT1 | cds-NP_116714.1_CAT1 | 85.8 | 100.0 | Mismatch | 1 | 1 | 0 | False | False | False | True | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005364.1:255840-256862:+ | gene-YFR055W_CBS1585 | rna-NM_001180021.1_CBS1585 | cds-NP_116714.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005348.1:228815-229837:+ | gene-YFR055W_CBS436 | rna-NM_001180021.1_CBS436 | cds-NP_116714.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005332.1:254913-255935:+ | gene-YFR055W_CBS6412 | rna-NM_001180021.1_CBS6412 | cds-NP_116714.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 0 | False | False | False | True | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005316.1:257587-258609:+ | gene-YFR055W_CBS6413 | rna-NM_001180021.1_CBS6413 | cds-NP_116714.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001527.1:260290-261312:+ | gene-YFR055W_CENPK1137D | rna-NM_001180021.1_CENPK1137D | cds-NP_116714.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005476.1:253461-254483:+ | gene-YFR055W_EthanolRed | rna-NM_001180021.1_EthanolRed | cds-NP_116714.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005540.1:255111-256133:+ | gene-YFR055W_FaliES1 | rna-NM_001180021.1_FaliES1 | cds-NP_116714.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000453.1:58342-59367:+ | gene-YFR055W_JAY291 | rna-NM_001180021.1_JAY291 | cds-NP_116714.1_JAY291 | 85.8 | 100.0 | Mismatch | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005412.1:258454-259476:+ | gene-YFR055W_MUCL30387 | rna-NM_001180021.1_MUCL30387 | cds-NP_116714.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005444.1:253934-254956:+ | gene-YFR055W_MUCL30388 | rna-NM_001180021.1_MUCL30388 | cds-NP_116714.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005284.1:253762-254784:+ | gene-YFR055W_MUCL39482 | rna-NM_001180021.1_MUCL39482 | cds-NP_116714.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005428.1:253373-254395:+ | gene-YFR055W_MUCL42920 | rna-NM_001180021.1_MUCL42920 | cds-NP_116714.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011815.1:264203-265225:+ | gene-YFR055W_NCIM3186 | rna-NM_001180021.1_NCIM3186 | cds-NP_116714.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005268.1:254611-255633:+ | gene-YFR055W_NCYC1407 | rna-NM_001180021.1_NCYC1407 | cds-NP_116714.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994145.1:296752-297777:+ | gene-YFR055W_PE2H3 | rna-NM_001180021.1_PE2H3 | cds-NP_116714.1_PE2H3 | 85.8 | 100.0 | Mismatch | 1 | 1 | 0 | False | False | False | True | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999877.1:296300-297325:+ | gene-YFR055W_PE2H4 | rna-NM_001180021.1_PE2H4 | cds-NP_116714.1_PE2H4 | 85.8 | 100.0 | Mismatch | 1 | 1 | 0 | False | False | False | True | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001138.5:264204-265226:+ | gene-YFR055W_S288C | rna-NM_001180021.1_S288C | cds-NP_116714.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000086.1:5784-6809:- | gene-YFR055W_SA1 | rna-NM_001180021.1_SA1 | cds-NP_116714.1_SA1 | 85.8 | 100.0 | Mismatch | 1 | 1 | 0 | False | False | False | True | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005492.1:254280-255302:+ | gene-YFR055W_ThermosaccDry | rna-NM_001180021.1_ThermosaccDry | cds-NP_116714.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005460.1:270136-271161:+ | gene-YFR055W_VR1 | rna-NM_001180021.1_VR1 | cds-NP_116714.1_VR1 | 85.8 | 100.0 | Mismatch | 1 | 1 | 0 | False | False | False | True | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000013.1:184723-185745:+ | gene-YFR055W_ZTW1 | rna-NM_001180021.1_ZTW1 | cds-NP_116714.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047492.1:280030-281052:+ | gene-YFR055W_Sparadoxus | rna-NM_001180021.1_Sparadoxus | cds-NP_116714.1_Sparadoxus | 90.7 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |