Gene name: IRC5
Reference locus (S288C): YFR038W
Gene biotype: protein_coding
Description: Uncharacterized ATP-dependent helicase IRC5; Putative ATPase containing the DEAD/H helicase-related sequence motif; null mutant displays increased levels of spontaneous Rad52p foci; SWAT-GFP and mCherry fusion proteins localize to the nucleus
Top 10 interactors (score): MCM3 (0.954); MCM2 (0.922); MCM5 (0.917); MCM4 (0.915); SMC2 (0.903); SPP1 (0.902); RAD51 (0.875); MSI1 (0.865); HAT2 (0.865); HAP5 (0.858); KIP1 (0.846); CIN8 (0.846); HIF1 (0.843); SPT16 (0.801); CMR1 (0.799); RSC8 (0.776); CTF4 (0.775); DPB4 (0.769); RAD52 (0.767); IRC24 (0.755)
Homologues (species, bitscore): HELLS (Homo sapiens, 474.2); Hells (Mus musculus, 489.6); hells (Danio rerio, 487.3); hells (Xenopus tropicalis, 500.4); Iswi (Drosophila melanogaster, 399.4); swsn-4 (Caenorhabditis elegans, 386.0); CHR1 (Arabidopsis thaliana, 425.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005300.1:219527-222088:+ | gene-YFR038W_AKU4011 | rna-NM_001180003.1_AKU4011 | cds-NP_116696.2_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000071.1:38918-41479:- | gene-YFR038W_BG1 | rna-NM_001180003.1_BG1 | cds-NP_116696.2_BG1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005508.1:223200-225761:+ | gene-YFR038W_Bruggeman | rna-NM_001180003.1_Bruggeman | cds-NP_116696.2_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005524.1:225138-227699:+ | gene-YFR038W_CAT1 | rna-NM_001180003.1_CAT1 | cds-NP_116696.2_CAT1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005364.1:221027-223588:+ | gene-YFR038W_CBS1585 | rna-NM_001180003.1_CBS1585 | cds-NP_116696.2_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005348.1:193996-196557:+ | gene-YFR038W_CBS436 | rna-NM_001180003.1_CBS436 | cds-NP_116696.2_CBS436 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005332.1:220102-222663:+ | gene-YFR038W_CBS6412 | rna-NM_001180003.1_CBS6412 | cds-NP_116696.2_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005316.1:222775-225336:+ | gene-YFR038W_CBS6413 | rna-NM_001180003.1_CBS6413 | cds-NP_116696.2_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001527.1:225469-228030:+ | gene-YFR038W_CENPK1137D | rna-NM_001180003.1_CENPK1137D | cds-NP_116696.2_CENPK1137D | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005476.1:218642-221203:+ | gene-YFR038W_EthanolRed | rna-NM_001180003.1_EthanolRed | cds-NP_116696.2_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005540.1:220292-222853:+ | gene-YFR038W_FaliES1 | rna-NM_001180003.1_FaliES1 | cds-NP_116696.2_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000453.1:23428-25989:+ | gene-YFR038W_JAY291 | rna-NM_001180003.1_JAY291 | cds-NP_116696.2_JAY291 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005412.1:223634-226195:+ | gene-YFR038W_MUCL30387 | rna-NM_001180003.1_MUCL30387 | cds-NP_116696.2_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005444.1:219114-221675:+ | gene-YFR038W_MUCL30388 | rna-NM_001180003.1_MUCL30388 | cds-NP_116696.2_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005284.1:218949-221510:+ | gene-YFR038W_MUCL39482 | rna-NM_001180003.1_MUCL39482 | cds-NP_116696.2_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005428.1:218551-221112:+ | gene-YFR038W_MUCL42920 | rna-NM_001180003.1_MUCL42920 | cds-NP_116696.2_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011815.1:229379-231940:+ | gene-YFR038W_NCIM3186 | rna-NM_001180003.1_NCIM3186 | cds-NP_116696.2_NCIM3186 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005268.1:219799-222360:+ | gene-YFR038W_NCYC1407 | rna-NM_001180003.1_NCYC1407 | cds-NP_116696.2_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994145.1:261838-264399:+ | gene-YFR038W_PE2H3 | rna-NM_001180003.1_PE2H3 | cds-NP_116696.2_PE2H3 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999877.1:261386-263947:+ | gene-YFR038W_PE2H4 | rna-NM_001180003.1_PE2H4 | cds-NP_116696.2_PE2H4 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001138.5:229380-231941:+ | gene-YFR038W_S288C | rna-NM_001180003.1_S288C | cds-NP_116696.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000086.1:39161-41722:- | gene-YFR038W_SA1 | rna-NM_001180003.1_SA1 | cds-NP_116696.2_SA1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005492.1:219461-222022:+ | gene-YFR038W_ThermosaccDry | rna-NM_001180003.1_ThermosaccDry | cds-NP_116696.2_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005460.1:235223-237784:+ | gene-YFR038W_VR1 | rna-NM_001180003.1_VR1 | cds-NP_116696.2_VR1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000013.1:149908-152469:+ | gene-YFR038W_ZTW1 | rna-NM_001180003.1_ZTW1 | cds-NP_116696.2_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047492.1:243010-245565:+ | gene-YFR038W_Sparadoxus | rna-NM_001180003.1_Sparadoxus | cds-NP_116696.2_Sparadoxus | 89.4 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |