Gene name: IRC3
Reference locus (S288C): YDR332W
Gene biotype: protein_coding
Description: Putative ATP-dependent helicase IRC3; Double-stranded DNA-dependent helicase of the DExH/D-box family; required for maintenance of the mitochondrial (mt) genome; null mutant accumulates double-stranded breaks in mt DNA; localizes to the mt matrix; Belongs to the helicase family. IRC3 subfamily
Top 10 interactors (score): HMI1 (0.924); IRC24 (0.838); OM14 (0.811); TFB2 (0.803); IRC21 (0.792); TFB5 (0.789); HRQ1 (0.777); TFB4 (0.775); TFB1 (0.772); KIN28 (0.77); TFB3 (0.766); RPO41 (0.759); MRH4 (0.752); ORI5 (0.747); MSS116 (0.747); SUV3 (0.744); INO80 (0.742); RAD54 (0.737); TFG2 (0.728); IRC20 (0.698)
Homologues (species, bitscore): EIF4A3 (Homo sapiens, 55.1); Gm8994 (Mus musculus, 57.0); eif4a3 (Danio rerio, 52.8); eif4a3 (Xenopus tropicalis, 52.4); CG32344 (Drosophila melanogaster, 52.0); Y71G12B.8 (Caenorhabditis elegans, 65.1); AT1G77030 (Arabidopsis thaliana, 62.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1077040-1079109:+ | gene-YDR332W_AKU4011 | rna-NM_001180640.3_AKU4011 | cds-NP_010619.3_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:52450-54519:- | gene-YDR332W_BG1 | rna-NM_001180640.3_BG1 | cds-NP_010619.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1104585-1106654:+ | gene-YDR332W_Bruggeman | rna-NM_001180640.3_Bruggeman | cds-NP_010619.3_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1091331-1093400:+ | gene-YDR332W_CAT1 | rna-NM_001180640.3_CAT1 | cds-NP_010619.3_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1071484-1073553:+ | gene-YDR332W_CBS1585 | rna-NM_001180640.3_CBS1585 | cds-NP_010619.3_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1089868-1091937:+ | gene-YDR332W_CBS436 | rna-NM_001180640.3_CBS436 | cds-NP_010619.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1068172-1070241:+ | gene-YDR332W_CBS6412 | rna-NM_001180640.3_CBS6412 | cds-NP_010619.3_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1089403-1091472:+ | gene-YDR332W_CBS6413 | rna-NM_001180640.3_CBS6413 | cds-NP_010619.3_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1129638-1131707:+ | gene-YDR332W_CENPK1137D | rna-NM_001180640.3_CENPK1137D | cds-NP_010619.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:252580-254649:+ | gene-YDR332W_EthanolRed | rna-NM_001180640.3_EthanolRed | cds-NP_010619.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1083795-1085864:+ | gene-YDR332W_FaliES1 | rna-NM_001180640.3_FaliES1 | cds-NP_010619.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000386.1:36309-38378:+ | gene-YDR332W_JAY291 | rna-NM_001180640.3_JAY291 | cds-NP_010619.3_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1089829-1091898:+ | gene-YDR332W_MUCL30387 | rna-NM_001180640.3_MUCL30387 | cds-NP_010619.3_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1078784-1080853:+ | gene-YDR332W_MUCL30388 | rna-NM_001180640.3_MUCL30388 | cds-NP_010619.3_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1063291-1065360:+ | gene-YDR332W_MUCL39482 | rna-NM_001180640.3_MUCL39482 | cds-NP_010619.3_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1010362-1012431:+ | gene-YDR332W_MUCL42920 | rna-NM_001180640.3_MUCL42920 | cds-NP_010619.3_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1130924-1132993:+ | gene-YDR332W_NCIM3186 | rna-NM_001180640.3_NCIM3186 | cds-NP_010619.3_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1076582-1078651:+ | gene-YDR332W_NCYC1407 | rna-NM_001180640.3_NCYC1407 | cds-NP_010619.3_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1087589-1089658:+ | gene-YDR332W_PE2H3 | rna-NM_001180640.3_PE2H3 | cds-NP_010619.3_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1093174-1095243:+ | gene-YDR332W_PE2H4 | rna-NM_001180640.3_PE2H4 | cds-NP_010619.3_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1131001-1133070:+ | gene-YDR332W_S288C | rna-NM_001180640.3_S288C | cds-NP_010619.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000025.1:101811-103880:+ | gene-YDR332W_SA1 | rna-NM_001180640.3_SA1 | cds-NP_010619.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1088068-1090137:+ | gene-YDR332W_ThermosaccDry | rna-NM_001180640.3_ThermosaccDry | cds-NP_010619.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1103985-1106054:+ | gene-YDR332W_VR1 | rna-NM_001180640.3_VR1 | cds-NP_010619.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:132178-134247:+ | gene-YDR332W_ZTW1 | rna-NM_001180640.3_ZTW1 | cds-NP_010619.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1083450-1085519:+ | gene-YDR332W_Sparadoxus | rna-NM_001180640.3_Sparadoxus | cds-NP_010619.3_Sparadoxus | 90.3 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |