Gene name: IRC25
Reference locus (S288C): YLR021W
Gene biotype: protein_coding
Description: Proteasome chaperone 3; Component of a heterodimeric Poc4p-Irc25p chaperone; involved in assembly of alpha subunits into the 20S proteasome; may regulate formation of proteasome isoforms with alternative subunits under different conditions; upregulates proteasome assembly in response to the unfolded protein response activated by mistargeting of proteins (UPRam); Belongs to the PSMG3 family
Top 10 interactors (score): POC4 (0.999); ADD66 (0.945); PBA1 (0.943); UMP1 (0.93); PUP2 (0.884); PRE6 (0.847); PRE9 (0.81); BLM10 (0.76); JNM1 (0.753); PAC2 (0.746); PUP1 (0.72); UBP16 (0.716); ECM29 (0.71); PAC1 (0.699); PRE1 (0.698); PRE2 (0.696); NAS6 (0.696); RPN14 (0.69); HSM3 (0.679); TMA17 (0.651)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:171562-172101:+ | gene-YLR021W_AKU4011 | rna-NM_001181908.1_AKU4011 | cds-NP_013121.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:134833-135372:+ | gene-YLR021W_BG1 | rna-NM_001181908.1_BG1 | cds-NP_013121.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:181957-182496:+ | gene-YLR021W_Bruggeman | rna-NM_001181908.1_Bruggeman | cds-NP_013121.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:182279-182818:+ | gene-YLR021W_CAT1 | rna-NM_001181908.1_CAT1 | cds-NP_013121.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:179186-179725:+ | gene-YLR021W_CBS1585 | rna-NM_001181908.1_CBS1585 | cds-NP_013121.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:169820-170359:+ | gene-YLR021W_CBS436 | rna-NM_001181908.1_CBS436 | cds-NP_013121.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:177597-178136:+ | gene-YLR021W_CBS6412 | rna-NM_001181908.1_CBS6412 | cds-NP_013121.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:179449-179988:+ | gene-YLR021W_CBS6413 | rna-NM_001181908.1_CBS6413 | cds-NP_013121.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:168873-169412:+ | gene-YLR021W_CENPK1137D | rna-NM_001181908.1_CENPK1137D | cds-NP_013121.1_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:171574-172113:+ | gene-YLR021W_EthanolRed | rna-NM_001181908.1_EthanolRed | cds-NP_013121.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:171144-171683:+ | gene-YLR021W_FaliES1 | rna-NM_001181908.1_FaliES1 | cds-NP_013121.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000431.1:15338-15877:+ | gene-YLR021W_JAY291 | rna-NM_001181908.1_JAY291 | cds-NP_013121.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:179304-179843:+ | gene-YLR021W_MUCL30387 | rna-NM_001181908.1_MUCL30387 | cds-NP_013121.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:185927-186466:+ | gene-YLR021W_MUCL30388 | rna-NM_001181908.1_MUCL30388 | cds-NP_013121.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:179681-180220:+ | gene-YLR021W_MUCL39482 | rna-NM_001181908.1_MUCL39482 | cds-NP_013121.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:179583-180122:+ | gene-YLR021W_MUCL42920 | rna-NM_001181908.1_MUCL42920 | cds-NP_013121.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:183597-184136:+ | gene-YLR021W_NCIM3186 | rna-NM_001181908.1_NCIM3186 | cds-NP_013121.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:171301-171840:+ | gene-YLR021W_NCYC1407 | rna-NM_001181908.1_NCYC1407 | cds-NP_013121.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:177616-178155:+ | gene-YLR021W_PE2H3 | rna-NM_001181908.1_PE2H3 | cds-NP_013121.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:177357-177896:+ | gene-YLR021W_PE2H4 | rna-NM_001181908.1_PE2H4 | cds-NP_013121.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:183623-184162:+ | gene-YLR021W_S288C | rna-NM_001181908.1_S288C | cds-NP_013121.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000046.1:15473-16012:+ | gene-YLR021W_SA1 | rna-NM_001181908.1_SA1 | cds-NP_013121.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:171648-172187:+ | gene-YLR021W_ThermosaccDry | rna-NM_001181908.1_ThermosaccDry | cds-NP_013121.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:185067-185606:+ | gene-YLR021W_VR1 | rna-NM_001181908.1_VR1 | cds-NP_013121.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:171013-171552:+ | gene-YLR021W_ZTW1 | rna-NM_001181908.1_ZTW1 | cds-NP_013121.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:179808-180350:+ | gene-YLR021W_Sparadoxus | rna-NM_001181908.1_Sparadoxus | cds-NP_013121.1_Sparadoxus | 90.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |