Gene name: IRC21
Reference locus (S288C): YMR073C
Gene biotype: protein_coding
Description: Increased recombination centers protein 21; Protein of unknown function; may be involved in resistance to carboplatin and cisplatin; null mutant displays increase in spontaneous Rad52p foci; contains a lipid-binding domain and binds cardiolipin in a large-scale study
Top 10 interactors (score): IRC24 (0.873); ALG7 (0.832); CYB5 (0.794); IRC3 (0.792); XRS2 (0.712); AIM33 (0.691); PGA3 (0.687); NST1 (0.666); IMP3 (0.651); IRC20 (0.65); MRPL1 (0.624); IRC15 (0.618); YKL075C (0.616); IRC5 (0.613); RMI1 (0.611); YAP1801 (0.6); YAP1802 (0.6); HRQ1 (0.6); TDA5 (0.598); MRE11 (0.592)
Homologues (species, bitscore): CYB5R4 (Homo sapiens, 69.3); Cyb5r4 (Mus musculus, 71.2); cyb5r4 (Danio rerio, 70.1); cyb5r4 (Xenopus tropicalis, 67.0); CG11257 (Drosophila melanogaster, 63.5); Y52B11A.3 (Caenorhabditis elegans, 64.3); RLF (Arabidopsis thaliana, 87.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:449973-450578:- | gene-YMR073C_AKU4011 | rna-NM_001182571.1_AKU4011 | cds-NP_013789.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:92205-92810:+ | gene-YMR073C_BG1 | rna-NM_001182571.1_BG1 | cds-NP_013789.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:392124-392729:- | gene-YMR073C_Bruggeman | rna-NM_001182571.1_Bruggeman | cds-NP_013789.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:392487-393092:- | gene-YMR073C_CAT1 | rna-NM_001182571.1_CAT1 | cds-NP_013789.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:382916-383521:- | gene-YMR073C_CBS1585 | rna-NM_001182571.1_CBS1585 | cds-NP_013789.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:388469-389074:- | gene-YMR073C_CBS436 | rna-NM_001182571.1_CBS436 | cds-NP_013789.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:495989-496594:- | gene-YMR073C_CBS6412 | rna-NM_001182571.1_CBS6412 | cds-NP_013789.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:382173-382778:- | gene-YMR073C_CBS6413 | rna-NM_001182571.1_CBS6413 | cds-NP_013789.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:406373-406978:- | gene-YMR073C_CENPK1137D | rna-NM_001182571.1_CENPK1137D | cds-NP_013789.1_CENPK1137D | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:382778-383383:- | gene-YMR073C_EthanolRed | rna-NM_001182571.1_EthanolRed | cds-NP_013789.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:385944-386549:- | gene-YMR073C_FaliES1 | rna-NM_001182571.1_FaliES1 | cds-NP_013789.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000033.1:50406-51011:+ | gene-YMR073C_JAY291 | rna-NM_001182571.1_JAY291 | cds-NP_013789.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:387856-388461:- | gene-YMR073C_MUCL30387 | rna-NM_001182571.1_MUCL30387 | cds-NP_013789.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:392544-393149:- | gene-YMR073C_MUCL30388 | rna-NM_001182571.1_MUCL30388 | cds-NP_013789.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:383204-383809:- | gene-YMR073C_MUCL39482 | rna-NM_001182571.1_MUCL39482 | cds-NP_013789.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:389857-390462:- | gene-YMR073C_MUCL42920 | rna-NM_001182571.1_MUCL42920 | cds-NP_013789.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:412222-412827:- | gene-YMR073C_NCIM3186 | rna-NM_001182571.1_NCIM3186 | cds-NP_013789.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:383116-383721:- | gene-YMR073C_NCYC1407 | rna-NM_001182571.1_NCYC1407 | cds-NP_013789.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:389068-389673:- | gene-YMR073C_PE2H3 | rna-NM_001182571.1_PE2H3 | cds-NP_013789.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:395163-395768:- | gene-YMR073C_PE2H4 | rna-NM_001182571.1_PE2H4 | cds-NP_013789.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:412268-412873:- | gene-YMR073C_S288C | rna-NM_001182571.1_S288C | cds-NP_013789.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000005.1:137296-137901:+ | gene-YMR073C_SA1 | rna-NM_001182571.1_SA1 | cds-NP_013789.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:383747-384352:- | gene-YMR073C_ThermosaccDry | rna-NM_001182571.1_ThermosaccDry | cds-NP_013789.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:395652-396257:- | gene-YMR073C_VR1 | rna-NM_001182571.1_VR1 | cds-NP_013789.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:362021-362626:- | gene-YMR073C_ZTW1 | rna-NM_001182571.1_ZTW1 | cds-NP_013789.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:395577-396182:- | gene-YMR073C_Sparadoxus | rna-NM_001182571.1_Sparadoxus | cds-NP_013789.1_Sparadoxus | 90.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |