Gene name: IRC18
Reference locus (S288C): YJL037W
Gene biotype: protein_coding
Description: Protein involved in outer spore wall assembly; possible role in assembly of the dityrosine layer; similar to adjacent ORF, LOH1; irc18 loh1 double mutant exhibits reduced dityrosine fluorescence relative to single mutants; SWAT-GFP fusion protein localizes to the ER and vacuole, while mCherry fusion localizes to the vacuole; expression induced in respiratory-deficient cells and carbon-limited chemostat culture; null mutant displays increased levels of spontaneous Rad52p foci; Belongs to the OSW4/6 family
Top 10 interactors (score): LDS2 (0.941); OSW7 (0.91); SHE10 (0.91); OSW2 (0.899); RRT8 (0.849); NPP1 (0.817); OSW5 (0.766); DTR1 (0.762); RRT12 (0.761); QDR1 (0.749); DIT2 (0.746); QDR3 (0.691); GAT3 (0.678); PAN5 (0.574); DIT1 (0.568); MIP6 (0.542); CDA1 (0.517); PES4 (0.503); YEL023C (0.499); LOH1 (0.417)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:359617-360291:+ | gene-YJL037W_AKU4011 | rna-NM_001181471.3_AKU4011 | cds-NP_012497.3_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:253790-254464:- | gene-YJL037W_BG1 | rna-NM_001181471.3_BG1 | cds-NP_012497.3_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:373068-373742:+ | gene-YJL037W_Bruggeman | rna-NM_001181471.3_Bruggeman | cds-NP_012497.3_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:377765-378439:+ | gene-YJL037W_CAT1 | rna-NM_001181471.3_CAT1 | cds-NP_012497.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:371281-371955:+ | gene-YJL037W_CBS1585 | rna-NM_001181471.3_CBS1585 | cds-NP_012497.3_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:389639-390313:+ | gene-YJL037W_CBS436 | rna-NM_001181471.3_CBS436 | cds-NP_012497.3_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:359879-360553:+ | gene-YJL037W_CBS6412 | rna-NM_001181471.3_CBS6412 | cds-NP_012497.3_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:361759-362433:+ | gene-YJL037W_CBS6413 | rna-NM_001181471.3_CBS6413 | cds-NP_012497.3_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:359088-359762:+ | gene-YJL037W_CENPK1137D | rna-NM_001181471.3_CENPK1137D | cds-NP_012497.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:362832-363506:+ | gene-YJL037W_EthanolRed | rna-NM_001181471.3_EthanolRed | cds-NP_012497.3_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:375280-375954:+ | gene-YJL037W_FaliES1 | rna-NM_001181471.3_FaliES1 | cds-NP_012497.3_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000200.1:39472-40146:- | gene-YJL037W_JAY291 | rna-NM_001181471.3_JAY291 | cds-NP_012497.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:374046-374720:+ | gene-YJL037W_MUCL30387 | rna-NM_001181471.3_MUCL30387 | cds-NP_012497.3_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:369945-370619:+ | gene-YJL037W_MUCL30388 | rna-NM_001181471.3_MUCL30388 | cds-NP_012497.3_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:364605-365279:+ | gene-YJL037W_MUCL39482 | rna-NM_001181471.3_MUCL39482 | cds-NP_012497.3_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:369942-370616:+ | gene-YJL037W_MUCL42920 | rna-NM_001181471.3_MUCL42920 | cds-NP_012497.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:376641-377315:+ | gene-YJL037W_NCIM3186 | rna-NM_001181471.3_NCIM3186 | cds-NP_012497.3_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:362554-363228:+ | gene-YJL037W_NCYC1407 | rna-NM_001181471.3_NCYC1407 | cds-NP_012497.3_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:374632-375306:+ | gene-YJL037W_PE2H3 | rna-NM_001181471.3_PE2H3 | cds-NP_012497.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:374276-374950:+ | gene-YJL037W_PE2H4 | rna-NM_001181471.3_PE2H4 | cds-NP_012497.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:376662-377336:+ | gene-YJL037W_S288C | rna-NM_001181471.3_S288C | cds-NP_012497.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000003.1:172162-172836:+ | gene-YJL037W_SA1 | rna-NM_001181471.3_SA1 | cds-NP_012497.3_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:368942-369616:+ | gene-YJL037W_ThermosaccDry | rna-NM_001181471.3_ThermosaccDry | cds-NP_012497.3_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:370788-371462:+ | gene-YJL037W_VR1 | rna-NM_001181471.3_VR1 | cds-NP_012497.3_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:349607-350281:+ | gene-YJL037W_ZTW1 | rna-NM_001181471.3_ZTW1 | cds-NP_012497.3_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:374808-375482:+ | gene-YJL037W_Sparadoxus | rna-NM_001181471.3_Sparadoxus | cds-NP_012497.3_Sparadoxus | 92.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |