Gene name: IRC15
Reference locus (S288C): YPL017C
Gene biotype: protein_coding
Description: Increased recombination centers protein 15; Microtubule associated protein; regulates microtubule dynamics; required for accurate meiotic chromosome segregation; null mutant displays large budded cells due to delayed mitotic progression, increased levels of spontaneous Rad52 foci; IRC15 has a paralog, LPD1, that arose from the whole genome duplication; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Top 10 interactors (score): PDB1 (0.998); LAT1 (0.998); KGD2 (0.984); PDX1 (0.965); LSC2 (0.945); MAS1 (0.929); ATP3 (0.926); QCR2 (0.918); PDA1 (0.895); ATP1 (0.876); GSH2 (0.87); GCV1 (0.842); KGD1 (0.816); FUM1 (0.804); MAD2 (0.791); MDH3 (0.771); MDH1 (0.771); GCV3 (0.769); LIP5 (0.768); GCV2 (0.763)
Homologues (species, bitscore): DLD (Homo sapiens, 268.9); Dld (Mus musculus, 264.6); dldh (Danio rerio, 272.3); dld (Xenopus tropicalis, 260.0); CG7430 (Drosophila melanogaster, 271.9); dld-1 (Caenorhabditis elegans, 271.2); mtLPD1 (Arabidopsis thaliana, 280.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:490223-491722:- | gene-YPL017C_AKU4011 | rna-NM_001183831.1_AKU4011 | cds-NP_015308.1_AKU4011 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:405622-407121:+ | gene-YPL017C_BG1 | rna-NM_001183831.1_BG1 | cds-NP_015308.1_BG1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:567172-568671:- | gene-YPL017C_Bruggeman | rna-NM_001183831.1_Bruggeman | cds-NP_015308.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:606836-608335:- | gene-YPL017C_CAT1 | rna-NM_001183831.1_CAT1 | cds-NP_015308.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:494295-495794:- | gene-YPL017C_CBS1585 | rna-NM_001183831.1_CBS1585 | cds-NP_015308.1_CBS1585 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:508422-509921:- | gene-YPL017C_CBS436 | rna-NM_001183831.1_CBS436 | cds-NP_015308.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:498486-499985:- | gene-YPL017C_CBS6412 | rna-NM_001183831.1_CBS6412 | cds-NP_015308.1_CBS6412 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:490848-492347:- | gene-YPL017C_CBS6413 | rna-NM_001183831.1_CBS6413 | cds-NP_015308.1_CBS6413 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:518695-520194:- | gene-YPL017C_CENPK1137D | rna-NM_001183831.1_CENPK1137D | cds-NP_015308.1_CENPK1137D | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:488587-490086:- | gene-YPL017C_EthanolRed | rna-NM_001183831.1_EthanolRed | cds-NP_015308.1_EthanolRed | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:496417-497916:- | gene-YPL017C_FaliES1 | rna-NM_001183831.1_FaliES1 | cds-NP_015308.1_FaliES1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000283.1:105019-106518:- | gene-YPL017C_JAY291 | rna-NM_001183831.1_JAY291 | cds-NP_015308.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:508120-509619:- | gene-YPL017C_MUCL30387 | rna-NM_001183831.1_MUCL30387 | cds-NP_015308.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:507228-508727:- | gene-YPL017C_MUCL30388 | rna-NM_001183831.1_MUCL30388 | cds-NP_015308.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:487613-489112:- | gene-YPL017C_MUCL39482 | rna-NM_001183831.1_MUCL39482 | cds-NP_015308.1_MUCL39482 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:546740-548239:- | gene-YPL017C_MUCL42920 | rna-NM_001183831.1_MUCL42920 | cds-NP_015308.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:518717-520216:- | gene-YPL017C_NCIM3186 | rna-NM_001183831.1_NCIM3186 | cds-NP_015308.1_NCIM3186 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:494890-496389:- | gene-YPL017C_NCYC1407 | rna-NM_001183831.1_NCYC1407 | cds-NP_015308.1_NCYC1407 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:501546-503045:- | gene-YPL017C_PE2H3 | rna-NM_001183831.1_PE2H3 | cds-NP_015308.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:501161-502660:- | gene-YPL017C_PE2H4 | rna-NM_001183831.1_PE2H4 | cds-NP_015308.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:518734-520233:- | gene-YPL017C_S288C | rna-NM_001183831.1_S288C | cds-NP_015308.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000076.1:15411-16910:- | gene-YPL017C_SA1 | rna-NM_001183831.1_SA1 | cds-NP_015308.1_SA1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:496216-497715:- | gene-YPL017C_ThermosaccDry | rna-NM_001183831.1_ThermosaccDry | cds-NP_015308.1_ThermosaccDry | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:511352-512851:- | gene-YPL017C_VR1 | rna-NM_001183831.1_VR1 | cds-NP_015308.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:495502-497001:- | gene-YPL017C_ZTW1 | rna-NM_001183831.1_ZTW1 | cds-NP_015308.1_ZTW1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:495461-496960:- | gene-YPL017C_Sparadoxus | rna-NM_001183831.1_Sparadoxus | cds-NP_015308.1_Sparadoxus | 85.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |